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EGF-like ligands:EGFR dimer [plasma membrane]
Stable Identifier
R-HSA-9624420
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by EGFR in Cancer (Homo sapiens)
Signaling by Overexpressed Wild-Type EGFR in Cancer (Homo sapiens)
Inhibition of Signaling by Overexpressed EGFR (Homo sapiens)
Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers (Homo sapiens)
EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane] (Homo sapiens)
EGF-like ligands:EGFR dimer [plasma membrane] (Homo sapiens)
EGF-like ligands:EGFR dimer [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by EGFR (Homo sapiens)
EGFR autophosphorylation (Homo sapiens)
EGF-like ligands:EGFR dimer [plasma membrane] (Homo sapiens)
EGFR dimerization (Homo sapiens)
EGF-like ligands:EGFR dimer [plasma membrane] (Homo sapiens)
Phosphorylation of EGFR by SRC kinase (Homo sapiens)
EGF-like ligands:EGFR dimer [plasma membrane] (Homo sapiens)
Participants
components
x 2
EGFR:EGF-like ligands [plasma membrane]
(Homo sapiens)
Participates
as a component of
EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane] (Homo sapiens)
as an input of
Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers (Homo sapiens)
EGFR autophosphorylation (Homo sapiens)
Phosphorylation of EGFR by SRC kinase (Homo sapiens)
as an output of
EGFR dimerization (Homo sapiens)
Inferred To
EGF-like ligands:EGFR dimer [plasma membrane]
(Bos taurus)
EGF-like ligands:EGFR dimer [plasma membrane]
(Caenorhabditis elegans)
EGF-like ligands:EGFR dimer [plasma membrane]
(Canis familiaris)
EGF-like ligands:EGFR dimer [plasma membrane]
(Danio rerio)
EGF-like ligands:EGFR dimer [plasma membrane]
(Drosophila melanogaster)
EGF-like ligands:EGFR dimer [plasma membrane]
(Gallus gallus)
EGF-like ligands:EGFR dimer [plasma membrane]
(Mus musculus)
EGF-like ligands:EGFR dimer [plasma membrane]
(Rattus norvegicus)
EGF-like ligands:EGFR dimer [plasma membrane]
(Sus scrofa)
EGF-like ligands:EGFR dimer [plasma membrane]
(Xenopus tropicalis)
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