Reactome | p-S345-NCF1 [cytosol]

p-S345-NCF1 [cytosol]

Stable Identifier

R-HSA-9626824

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

p-S345-p47phox

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P14598 NCF1

Gene Names

NCF1, NOXO2, SH3PXD1A

Chain

chain:1-390

Reference Genes

BioGPS Gene:653361 NCF1

COSMIC (genes):NCF1 NCF1

CTD Gene:653361 NCF1

dbSNP Gene:653361 NCF1

ENSEMBL:ENSG00000158517 NCF1

ENSEMBL_homo_sapiens_GENE:ENSG00000158517.16 NCF1

HGNC:7660 NCF1

KEGG Gene (Homo sapiens):653361 NCF1

Monarch:653361 NCF1

NCBI Gene:653361 NCF1

OMIM:608512 NCF1

UCSC:P14598 NCF1

Reference Transcript

RefSeq:NM_000265.5 NCF1

Other Identifiers

11746014_s_at

204961_3p_s_at

204961_PM_s_at

204961_s_at

214084_3p_x_at

214084_PM_x_at

214084_x_at

3007742

3007745

3007746

3007747

3007749

3007751

3007753

3007754

3007755

3007758

3007760

3007761

3007762

3007763

3007764

3007765

3007766

3008478

3008479

3008481

3008482

3008484

3008485

3008487

3008488

3008489

3008491

3008494

3008495

3008496

3008497

3008498

3008499

3056907

3056908

3056909

3056910

3056911

3056913

3056917

3056918

3056920

3056922

3056924

3056925

3056926

3056930

40159_r_at

653361

8133314

8133518

8140227

A_32_P116203

A_33_P3211432

A_33_P3224803

A_33_P3369393

GE57968

GO:0002376

GO:0003824

GO:0005515

GO:0005737

GO:0005764

GO:0005773

GO:0005829

GO:0005886

GO:0006091

GO:0006351

GO:0006355

GO:0006612

GO:0006801

GO:0006886

GO:0006954

GO:0006968

GO:0008289

GO:0009055

GO:0009898

GO:0016020

GO:0016175

GO:0016176

GO:0016491

GO:0017124

GO:0022900

GO:0023052

GO:0030425

GO:0031410

GO:0032010

GO:0034614

GO:0035091

GO:0036211

GO:0042554

GO:0043020

GO:0043025

GO:0043226

GO:0043325

GO:0045087

GO:0045730

GO:0045741

GO:0045893

GO:0046330

GO:0051897

GO:0060264

GO:0071276

GO:0071333

GO:0071394

GO:0098542

GO:0098772

GO:1900745

GO:1903409

HMNXSV003039349

HMNXSV003055897

HMNXSV003058199

Hs.1583.1.S1_3p_at

Hs.1583.1.S1_3p_s_at

Hs.1583.1.S1_3p_x_at

M55067_at

PH_hs_0035298

TC07000438.hg

TC07001516.hg

TC07002399.hg

TC07003026.hg

g4557784_3p_a_at

g4557784_3p_s_at

g4557784_3p_x_at

Participates

as a component of

Other forms of this molecule

NCF1 [cytosol]

p-6S-NCF1 [phagolysosome]

p-6S-NCF1 [cytosol]

Inferred To

phospho-Ncf1 [cytosol] (Mus musculus)

phospho-Ncf1 [cytosol] (Rattus norvegicus)

phospho-BEM1 [cytosol] (Saccharomyces cerevisiae)

phospho-scd2 [cytosol] (Schizosaccharomyces pombe)

phospho-p-S345-NCF1 [cytosol] (Gallus gallus)

phospho-ncf1 [cytosol] (Danio rerio)

phospho-ncf1 [cytosol] (Xenopus tropicalis)

phospho-NCF1 [cytosol] (Bos taurus)

phospho-NCF1 [cytosol] (Canis familiaris)

phospho-NCF1 [cytosol] (Sus scrofa)

Modified Residues

Name

O-phospho-L-serine at 345

Coordinate

345

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_000256.4

OpenTargets

ENSG00000158517

GeneCards

P14598

HPA

ENSG00000158517-NCF1

Ensembl

ENSP00000289473, ENSG00000158517, ENST00000289473

PRO

P14598

Pharos - Targets

P14598

Orphanet

16519

PDB

1GD5, 1W70, 1NG2, 1OV3, 7YXW, 1WLP, 1O7K, 1KQ6, 1UEC, 1K4U, 8WEJ

HMDB Protein

HMDBP02126

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q04206 RELA	7	MeK310-RELA [nucleoplasm] (R-HSA-8865233) p-S536-RELA [nucleoplasm] (R-HSA-9861499) p-S276,5xAcK-RELA [nucleoplasm] (R-HSA-5660642) p-S276-RELA [nucleoplasm] (R-HSA-5624468) polySUMO3-K37,K122,K123-RELA [nucleoplasm] (R-HSA-4755466) RELA [cytosol] (R-HSA-168172) RELA [nucleoplasm] (R-HSA-177676)	0.682	8
UniProt:P60709 ACTB	5	Unfolded ACTB [cytosol] (R-HSA-390462) ACTB [nucleoplasm] (R-HSA-3321990) ACTB [cytosol] (R-HSA-201861) ACTB [lysosomal membrane] (R-HSA-196160) ACTB [plasma membrane] (R-HSA-196016)	0.558	3
UniProt:P78325 ADAM8	4	ADAM8 [specific granule membrane] (R-HSA-6799563) ADAM8 [ficolin-1-rich granule membrane] (R-HSA-6801017) ADAM8 [plasma membrane] (R-HSA-708331) ADAM8 [tertiary granule membrane] (R-HSA-6800884)	0.558	2
UniProt:Q05513 PRKCZ	5	p-T410,T563-PRKCZ [cytosol] (R-HSA-5218698) PRKCZ [cytosol] (R-HSA-58218) PRKCZ [cell junction] (R-HSA-2134483) p-T410-PRKCZ [cytosol] (R-HSA-437181) pS, p-T410-PRKCZ [cytosol] (R-HSA-9632824)	0.556	3
UniProt:P06396 GSN	7	GSN(200-270) [extracellular region] (R-HSA-976940) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	6
UniProt:P11142 HSPA8	10	Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [cytosol] (R-HSA-264476)	0.499	2

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