Reactome | 3OHK21-DRG2 [cytosol]

3OHK21-DRG2 [cytosol]

Stable Identifier

R-HSA-9629595

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

hydroxylated Developmentally-regulated GTP-binding protein 2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P55039 DRG2

Gene Names

DRG2

Chain

chain:1-364

Reference Genes

BioGPS Gene:1819 DRG2

COSMIC (genes):DRG2 DRG2

CTD Gene:1819 DRG2

dbSNP Gene:1819 DRG2

ENSEMBL:ENSG00000108591 DRG2

HGNC:3030 DRG2

Monarch:1819 DRG2

NCBI Gene:1819 DRG2

OMIM:602986 DRG2

UCSC:P55039 DRG2

Reference Transcript

RefSeq:NM_001388.4 DRG2

Other Identifiers

11742894_a_at

11742895_a_at

11760145_a_at

16831681

1819

203267_PM_s_at

203267_s_at

203268_PM_s_at

203268_s_at

3712950

3712951

3712954

3712955

3712956

3712957

3712958

3712959

3712960

3712961

3712962

3712963

3712964

3712965

3712966

3712967

3712968

3712971

3712972

3712973

3712974

3712975

3712976

3712977

3712979

3712980

37664_at

8005313

A_23_P141656

GE475975

GE80180

GO:0000166

GO:0002181

GO:0003723

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0007165

GO:0016020

GO:0016787

GO:0043226

GO:0043231

GO:0046872

HMNXSV003000958

HMNXSV003041999

Hs.78582.0.S1_3p_a_at

ILMN_1810531

PH_hs_0004531

TC17000204.hg

X80754_at

g4557536_3p_a_at

Participates

as a component of

3OHK21-DRG2:RWDD1 [cytosol] (Homo sapiens)

Other forms of this molecule

DRG2 [cytosol]

Inferred To

Dmel\CG6195 [cytosol] (Drosophila melanogaster)

Drg2 [cytosol] (Rattus norvegicus)

3OHK21-DRG2 [cytosol] (Bos taurus)

3OHK21-DRG2 [cytosol] (Caenorhabditis elegans)

3OHK21-DRG2 [cytosol] (Dictyostelium discoideum)

3OHK21-DRG2 [cytosol] (Mus musculus)

3OHK21-DRG2 [cytosol] (Plasmodium falciparum)

3OHK21-DRG2 [cytosol] (Saccharomyces cerevisiae)

3OHK21-DRG2 [cytosol] (Schizosaccharomyces pombe)

drg2 [cytosol] (Xenopus tropicalis)

DRG2 [cytosol] (Canis familiaris)

DRG2 [cytosol] (Gallus gallus)

DRG2 [cytosol] (Sus scrofa)

Modified Residues

Name

monohydroxylated lysine at 21

Coordinate

PsiMod Name

monohydroxylated lysine

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to a monohydroxylated lysine.

Cross References

ENSEMBL

ENST00000225729, ENSP00000225729

OpenTargets

ENSG00000108591

HPA

ENSG00000108591-DRG2

PRO

P55039

Pharos - Targets

P55039

GlyGen

P55039

HMDB Protein

HMDBP08362

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38919 EIF4A3	2	EIF4A3 [nucleoplasm] (R-HSA-8849149) EIF4A3 [cytosol] (R-HSA-927868)	0.556	3
UniProt:Q15742 NAB2	1	NAB2 [nucleoplasm] (R-HSA-9612177)	0.556	3
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	2