p16INK4A G35W [cytosol]

Stable Identifier
R-HSA-9631328
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p16INK4A Gly35Trp, CDKN2A G35W, CDKN2A Gly35Trp
p16INK4A G35W [cytosol] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
24659262 CDKN2A unclassified variants in familial malignant melanoma: combining functional and computational approaches for their assessment

Scaini, MC, Minervini, G, Elefanti, L, Ghiorzo, P, Pastorino, L, Tognazzo, S, Agata, S, Quaggio, M, Zullato, D, Bianchi-ScarrĂ , G, Montagna, M, D'Andrea, E, Menin, C, Tosatto, SC

Hum. Mutat. 2014
External Reference Information
External Reference
Gene Names
CDKN2A, CDKN2, MTS1
Chain
chain:1-156
Other Identifiers
0002570204
0005130288
0101400494
1029
11718293_a_at
1713_s_at
207039_at
209644_x_at
211156_at
3201444
3201445
3201446
3201447
3201448
3201450
3201451
3201457
3201458
3201459
3201460
3201461
3201464
3201465
3201466
3201467
3201468
3201469
3201470
3201477
3201478
3201483
3201485
73132_r_at
8160441
A_23_P43484
A_23_P43490
A_33_P3411628
GE59038
GO:0000082
GO:0000278
GO:0001953
GO:0003674
GO:0003723
GO:0004861
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005694
GO:0005737
GO:0005829
GO:0006464
GO:0006950
GO:0007049
GO:0007050
GO:0007155
GO:0007165
GO:0007265
GO:0007568
GO:0008134
GO:0008150
GO:0008219
GO:0008283
GO:0008285
GO:0009058
GO:0016301
GO:0016310
GO:0019899
GO:0019901
GO:0022607
GO:0030234
GO:0030308
GO:0032088
GO:0034393
GO:0034641
GO:0035985
GO:0035986
GO:0040007
GO:0042326
GO:0043226
GO:0045736
GO:0045892
GO:0051059
GO:0051276
GO:0090398
GO:0090399
GO:2000111
GO:2000134
GO:2000774
HMNXSV003019577
ILMN_1717714
ILMN_1757255
PH_hs_0019731
U26727_at
g1353569_3p_a_at
g1353569_3p_x_at
g4206166_3p_a_at
g4502748_3p_at
Participates
Other forms of this molecule
Modified Residues
Name
glycine 35 replaced with L-tryptophan
Coordinate
35
PsiMod
A protein modification that effectively removes or replaces an glycine.
A protein modification that effectively converts a source amino acid residue to L-tryptophan.
Disease
Name Identifier Synonyms
lung squamous cell carcinoma DOID:3907 squamous cell carcinoma of lung (disorder), Epidermoid cell carcinoma of the lung
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Interactors (11)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P11802 CDK4  3 0.952 16
 UniProt:Q00534 CDK6  3 0.934 15
 UniProt:P12004 PCNA  5 0.61 8
 UniProt:P02730 SLC4A1  8 0.602 5
 UniProt:Q6UXH1 CREL2      0.508 2
 UniProt:Q8NHU6 TDRD7      0.508 2
 UniProt:O75398 DEAF1      0.508 2
 UniProt:Q00839 HNRNPU  1 0.508 2
 UniProt:Q14566 MCM6  1 0.499 4
 UniProt:P24385 CCND1  4 0.491 2
 UniProt:P62826 RAN  2 0.463 2
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