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C12orf66 [lysosomal membrane]
Stable Identifier
R-HSA-9638229
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal membrane
Synonyms
fullName evidence="6"KICSTOR complex protein C12orf66, CL066_HUMAN
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to starvation (Homo sapiens)
Amino acids regulate mTORC1 (Homo sapiens)
BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 (Homo sapiens)
KICSTOR:GATOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:BMT2 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR2 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
RRAGA,B hydrolyzes GTP (Homo sapiens)
KICSTOR:GATOR1:BMT2 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR2 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:SESN1,2 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
SESN1,2 binds L-leucine and dissociates from GATOR2 (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:SESN1,2 [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1 [lysosomal membrane] (Homo sapiens)
KICSTOR [lysosomal membrane] (Homo sapiens)
C12orf66 [lysosomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96MD2 KICS2
Gene Names
KICS2, C12orf66
Chain
chain:1-445
Reference Genes
BioGPS Gene:144577 KICS2
CTD Gene:144577 KICS2
dbSNP Gene:144577 KICS2
ENSEMBL:ENSG00000174206 C12orf66
ENSEMBL_homo_sapiens_GENE:ENSG00000174206.13 KICS2
HGNC:26517 KICS2
KEGG Gene (Homo sapiens):144577 KICS2
Monarch:144577 KICS2
NCBI Gene:144577 KICS2
OMIM:617420 KICS2
UCSC:Q96MD2 KICS2
Reference Transcript
RefSeq:NM_152440.4 KICS2
Other Identifiers
11731699_s_at
11731700_a_at
144577
16767009
235026_PM_at
235026_at
3459968
3459969
3459970
3459971
3459972
3459973
3459974
3459975
3459976
3459979
3459984
3459985
3459986
47871_at
60283_at
7964677
A_23_P370569
GE623456
GO:0005764
GO:0005765
GO:0005773
GO:0016020
GO:0023052
GO:0034198
GO:0042149
GO:0043226
GO:0045171
GO:0061462
GO:0140007
GO:1904262
HMNXSV003015029
HMNXSV003036688
Hs.73605.0.A1_3p_at
ILMN_1736995
ILMN_1883239
PH_hs_0021489
PH_hs_0024568
TC12001670.hg
Participates
as a component of
KICSTOR [lysosomal membrane] (Homo sapiens)
Inferred To
kics2 [lysosomal membrane]
(Xenopus tropicalis)
KICS2 [lysosomal membrane]
(Bos taurus)
KICS2 [lysosomal membrane]
(Canis familiaris)
KICS2 [lysosomal membrane]
(Gallus gallus)
KICS2 [lysosomal membrane]
(Sus scrofa)
C12orf66 [lysosomal membrane]
(Dictyostelium discoideum)
Kics2 [lysosomal membrane]
(Mus musculus)
Kics2 [lysosomal membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_689653.3
OpenTargets
ENSG00000174206
GeneCards
Q96MD2
HPA
ENSG00000174206-KICS2
Ensembl
ENST00000398055
,
ENSG00000174206
,
ENSP00000381132
PRO
Q96MD2
Pharos - Targets
Q96MD2
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