Reactome | Misfolded IFT88 [cilium]

Misfolded IFT88 [cilium]

Stable Identifier

R-HSA-9640106

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cilium

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q13099 IFT88

Gene Names

IFT88, TG737, TTC10

Chain

chain:1-824

Reference Genes

BioGPS Gene:8100 IFT88

COSMIC (genes):IFT88 IFT88

CTD Gene:8100 IFT88

dbSNP Gene:8100 IFT88

ENSEMBL:ENSG00000032742 IFT88

ENSEMBL:ENSG00000032742.18 IFT88

HGNC:20606 IFT88

KEGG Gene (Homo sapiens):8100 IFT88

Monarch:8100 IFT88

NCBI Gene:8100 IFT88

OMIM:600595 IFT88

UCSC:Q13099 IFT88

Reference Transcript

Other Identifiers

11721726_a_at

11748955_a_at

11748956_x_at

16772994

204703_PM_at

204703_at

34284_at

3480415

3480417

3480419

3480421

3480423

3480424

3480426

3480427

3480428

3480429

3480430

3480431

3480432

3480433

3480434

3480435

3480456

3480457

3480458

3480461

3480462

3480465

3480466

3480467

3480468

3480469

3480471

3480479

3480480

3480486

3480498

3480501

3480502

3480503

3480504

7967933

8100

A_14_P106901

A_14_P125798

A_23_P48339

GE58997

GO:0001822

GO:0005515

GO:0005737

GO:0005813

GO:0005814

GO:0005815

GO:0005829

GO:0005856

GO:0005929

GO:0006914

GO:0007018

GO:0008092

GO:0019894

GO:0030030

GO:0030154

GO:0030992

GO:0031514

GO:0034021

GO:0035720

GO:0036064

GO:0036126

GO:0042073

GO:0042995

GO:0043226

GO:0044782

GO:0045724

GO:0048856

GO:0060122

GO:0060271

GO:0097542

GO:0097546

GO:0097730

GO:1902017

GO:1905515

GO:2000785

HMNXSV003034453

HMNXSV003037033

ILMN_1666560

ILMN_1669366

ILMN_2373755

PH_hs_0023237

TC13000025.hg

U20362_at

g5729799_3p_at

Participates

as a member of

Misfolded cilia proteins [cilium] (Homo sapiens)

Other forms of this molecule

IFT88 [ciliary tip]

PolyUb-Misfolded IFT88 [late endosome lumen]

IFT88 [cilium]

PolyUb-Misfolded IFT88 [lysosomal lumen]

PolyUb-Misfolded IFT88 [cytosol]

Ub-Misfolded IFT88 [cytosol]

Misfolded IFT88 [cytosol]

Cross References

RefSeq

XP_005266610.1, NP_783195.2, NP_001305420.1, XP_006719933.1, XP_011533545.1, XP_016876246.1, NP_006522.2, XP_011533543.1, XP_011533544.1, XP_016876247.1

OpenTargets

ENSG00000032742

GeneCards

Q13099

HPA

ENSG00000032742-IFT88

Ensembl

ENSG00000032742, ENST00000319980, ENSP00000261632, ENSP00000323580, ENST00000351808

PRO

Q13099

Pharos - Targets

Q13099

Interactors (25)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9P2H3 IFT80	2	IFT80 [cilium] (R-HSA-5617613) IFT80 [ciliary tip] (R-HSA-5625367)	0.643	8
UniProt:Q9UG01 IFT172	2	IFT172 [ciliary tip] (R-HSA-5625353) IFT172 [cilium] (R-HSA-5610383)	0.643	9
UniProt:Q9NWB7 IFT57	2	IFT57 [cilium] (R-HSA-5610389) IFT57 [ciliary tip] (R-HSA-5625363)	0.643	6
UniProt:Q9Y547 IFT25	2	HSPB11 [ciliary tip] (R-HSA-5625342) HSPB11 [cilium] (R-HSA-5617628)	0.643	5
UniProt:Q9Y366 IFT52	2	IFT52 [ciliary tip] (R-HSA-5625360) IFT52 [cilium] (R-HSA-5610387)	0.643	6
UniProt:Q8N4P2 IFT70B	2	TTC30B [ciliary tip] (R-HSA-5637970) TTC30B [cilium] (R-HSA-5637971)	0.643	6
UniProt:Q8WYA0 IFT81	2	IFT81 [cilium] (R-HSA-5617769) IFT81 [ciliary tip] (R-HSA-5625369)	0.643	6
UniProt:Q86WT1 IFT70A	2	TTC30A [ciliary tip] (R-HSA-5637966) TTC30A [cilium] (R-HSA-5637968)	0.643	7
UniProt:A0AVF1 IFT56	2	TTC26 [ciliary tip] (R-HSA-5637962) TTC26 [cilium] (R-HSA-5637963)	0.643	6
UniProt:Q9H7X7 IFT22	2	RABL5 [cilium] (R-HSA-5617605) RABL5 [ciliary tip] (R-HSA-5625388)	0.643	6
UniProt:Q9BW83 IFT27	2	IFT27 [ciliary tip] (R-HSA-5625357) IFT27 [cilium] (R-HSA-5617621)	0.643	7
UniProt:Q96LB3 IFT74	2	IFT74 [cilium] (R-HSA-5617616) IFT74 [ciliary tip] (R-HSA-5625364)	0.643	7
UniProt:Q8IY31 IFT20	3	IFT20 [cilium] (R-HSA-5617624) IFT20 [Golgi membrane] (R-HSA-5617625) IFT20 [ciliary tip] (R-HSA-5625355)	0.643	6
UniProt:Q9NQC8 IFT46	2	IFT46 [ciliary tip] (R-HSA-5625359) IFT46 [cilium] (R-HSA-5617617)	0.643	7
UniProt:Q96AJ1 CLUAP1	2	CLUAP [ciliary tip] (R-HSA-5637957) CLUAP [cilium] (R-HSA-5637960)	0.592	4
UniProt:Q8TDR0 TRAF3IP1	2	TRAF3IP1 [ciliary tip] (R-HSA-5625404) TRAF3IP1 [cilium] (R-HSA-5617603)	0.592	4
UniProt:Q969G3 SMARCE1	1	SMARCE1 [nucleoplasm] (R-HSA-389258)	0.556	3
UniProt:Q9Y6W3 CAPN7	1	CAPN7 [cytosol] (R-HSA-8848633)	0.556	3
UniProt:Q96HB5 CC120			0.556	3
UniProt:A0A0C4DGQ7 A0A0C4DGQ7			0.556	3
UniProt:Q96G04 EEF2KMT	1	EEF2KMT [cytosol] (R-HSA-8876690)	0.556	3
UniProt:Q9NZV6 MSRB1	1	MSRB1 [cytosol] (R-HSA-5676936)	0.556	3
UniProt:P27987 ITPKB	1	ITPKB [cytosol] (R-HSA-1604605)	0.556	3
UniProt:O60303 KATIP			0.482	2
UniProt:Q13099 IFT88	8	IFT88 [ciliary tip] (R-HSA-5625371) PolyUb-Misfolded IFT88 [late endosome lumen] (R-HSA-9660031) IFT88 [cilium] (R-HSA-5610385) PolyUb-Misfolded IFT88 [lysosomal lumen] (R-HSA-9660026) PolyUb-Misfolded IFT88 [cytosol] (R-HSA-9641125) Ub-Misfolded IFT88 [cytosol] (R-HSA-9641114) Misfolded IFT88 [cytosol] (R-HSA-9640115) Misfolded IFT88 [cilium] (R-HSA-9640106)	0.462	4

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