p-S54-PDE4B hydrolyses cAMP

Stable Identifier
R-HSA-9644869
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
cAMP hydrolysis by PDE4B
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cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B) hydrolyzes cAMP to AMP (Huston et al. 1997). Phosphorylation of serine 54 on PDE4B increases its activity.

Literature References
PubMed ID Title Journal Year
9371714 Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3

Huston, E, Lumb, S, Russell, A, Catterall, C, Ross, AH, Steele, MR, Bolger, GB, Perry, MJ, Owens, RJ, Houslay, MD

Biochem J 1997
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
3',5'-cyclic-AMP phosphodiesterase activity of p-S54-PDE4B [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created