NRAS Q61H [plasma membrane]

Stable Identifier
R-HSA-9649678
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Icon
NRAS Q61H [plasma membrane] icon
NRAS Q61H [plasma membrane] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P01111 NRAS
Gene Names
NRAS, HRAS1
Chain
chain:1-186, propeptide:187-189
Reference Genes
BioGPS Gene:4893 NRAS
COSMIC (genes):NRAS NRAS
CTD Gene:4893 NRAS
dbSNP Gene:4893 NRAS
ENSEMBL:ENSG00000213281 NRAS
HGNC:7989 NRAS
KEGG Gene (Homo sapiens):4893 NRAS
Monarch:4893 NRAS
NCBI Gene:4893 NRAS
OMIM:164790 NRAS
Reference Transcript
Other Identifiers
0001340273
10157
11719188_at
11719189_at
1539_at
16691262
202647_s_at
224985_at
2429260
2429262
2429263
2429264
2429265
2429266
2429267
2429268
2429270
2429271
2429273
2429274
2N9C
3CON
4893
49830
5UHV
7918813
A_23_P63190
A_33_P3317825
AAA36548
AAA36556
AAA60255
AAH05219
AAM12633
AAQ94397
AAV38539
AAV38540
ABY87546
AF493919
AY428630
BC005219
BT019734
BT019735
CAA25269
CAA25270
CAA25271
CAA25272
CAA26529
CAA29079
CAA30320
CAA37384
CAB010157
CCDS877
CH471122
EAW56608
EAW56609
EAW56610
EAW56611
ENSG00000213281
ENSP00000358548
ENST00000369535
ENST00000369535.4
EntrezGene:4893
EntrezGene:NRAS
EU332857
g6006027_3p_a_at
GE79523
GO:0000139
GO:0000165
GO:0000166
GO:0001938
GO:0002223
GO:0002376
GO:0003674
GO:0003924
GO:0005515
GO:0005525
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005794
GO:0005886
GO:0006464
GO:0006810
GO:0006950
GO:0007165
GO:0007265
GO:0008150
GO:0008283
GO:0016020
GO:0016192
GO:0019003
GO:0031410
GO:0043167
GO:0043226
GO:0043312
GO:0044877
GO:0070062
GO:0070821
HGNC:7989
HPA049830
Hs.260523.1.A1_3p_at
ILMN_1775759
IPR001806
IPR005225
IPR020849
IPR027417
K03211
L00040
L00041
L00042
L00043
LRG_92
M10055
M25898
MIM:114500
MIM:137550
MIM:162900
MIM:163200
MIM:164790
MIM:188470
MIM:249400
MIM:613224
MIM:614470
NM_002524
NP_002515
NRAS
NRAS-201
PF00071
PH_hs_0013620
PR00449
Q5U091
SM00173
SM00174
SM00175
TC01003014.hg
UPI0000001254
X00642
X00643
X00644
X00645
X02751
X02751_at
X05565
X07440
X53291
X53292
Participant Of
hasCandidate
Other forms of this molecule
NRAS [tertiary granule membrane]
NRAS [plasma membrane]
NRAS G13R [plasma membrane]
NRAS G13V [plasma membrane]
NRAS G13C [plasma membrane]
NRAS G12V [plasma membrane]
NRAS G12C [plasma membrane]
S-Farn-Me PalmS NRAS [plasma membrane]
NRAS Q60E [plasma membrane]
NRAS G12D [plasma membrane]
NRAS G12S [plasma membrane]
NRAS G13D [plasma membrane]
NRAS Q61K [plasma membrane]
NRAS Q61L [plasma membrane]
NRAS Q61R [plasma membrane]
NRAS Q61P [plasma membrane]
NRAS G12A [plasma membrane]
NRAS G12R [plasma membrane]
Modified Residues
Name
L-glutamine 61 replaced with L-histidine
Coordinate
61
PsiMod
L-histidine residue [MOD:00018]
A protein modification that effectively converts a source amino acid residue to an L-histidine.
L-glutamine removal [MOD:01637]
A protein modification that effectively removes or replaces an L-glutamine.
Disease
Name Identifier Synonyms
melanoma 1909 Naevocarcinoma, melanoma, melanoma, malignant melanoma, morphology (morphologic abnormality), malignant melanoma NOS (morphologic abnormality), malignant melanoma (disorder), malignant melanoma, malignant melanoma, malignant melanoma, malignant melanoma
lung cancer 1324
hematologic cancer 2531 hematopoietic cancer, hematopoietic tumors, Hematologic neoplasm (disorder), Hematologic malignancy, hematopoietic neoplasm (morphologic abnormality), Hematologic malignancy (disorder), Hematological tumors, blood cancer, hematopoietic and lymphoid system tumor, malignant hematopoietic neoplasm (morphologic abnormality)
Cross References
RefSeq
COSMIC
OpenTargets
ZINC - Substances
GeneCards
ZINC target
PRO
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
PDB
Interactors (4)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P04049 RAF1  10 0.802 5
 UniProt:P15056 BRAF  68 0.591 3
 UniProt:Q99N57  10 0.499 2
 UniProt:P28028  6 0.499 2