THTPA:Mg2+ hydrolyzes ThTP to TDP

Stable Identifier
R-HSA-965067
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
Thiamin triphosphate can be hydrolysed back to thiamin diphosphate
Locations in the PathwayBrowser
Summation

Thiamin triphosphate (ThTP) can transfer phosphate to a few proteins. Animal tissues contain a membrane-associated as well as a soluble thiamine triphosphatase that can dephosphorylate ThTP. Only the soluble enzyme was characterized in calf (Lakaye et al, 2002).

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
thiamin-triphosphatase activity of THTPA:Mg2+ [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea