Reactome | CBX1 [nucleoplasm]

CBX1 [nucleoplasm]

Stable Identifier

R-HSA-9653629

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Chromobox protein homolog 1, CBX1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P83916 CBX1

Gene Names

CBX1, CBX

Chain

chain:1-185

Reference Genes

BioGPS Gene:10951 CBX1

COSMIC (genes):CBX1 CBX1

CTD Gene:10951 CBX1

dbSNP Gene:10951 CBX1

ENSEMBL:ENSG00000108468 CBX1

HGNC:1551 CBX1

KEGG Gene (Homo sapiens):10951 CBX1

Monarch:10951 CBX1

NCBI Gene:10951 CBX1

OMIM:604511 CBX1

Reference Transcript

Other Identifiers

0006290358

11715546_s_at

16846181

201518_at

37304_at

3761126

3761128

3761129

3761130

3761132

3761133

3761134

3761135

3761138

3761139

3761140

3761141

4010449

4010450

4010451

8016402

A_23_P107507

A_24_P296568

GE59106

GO:0000228

GO:0000775

GO:0000784

GO:0000785

GO:0001939

GO:0001940

GO:0003674

GO:0003682

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005694

GO:0005720

GO:0005721

GO:0005819

GO:0005856

GO:0006950

GO:0006974

GO:0008150

GO:0009058

GO:0010369

GO:0019899

GO:0034641

GO:0042802

GO:0043226

GO:0045892

GO:0090734

GO:1990226

ILMN_1770244

PH_hs_0027694

TC17001635.hg

U35451_at

g5803075_3p_at

Participant Of

output

Activation of Latent HCMV Genome

hasComponent

Latent Transcriptionally Repressed HCMV Genome [nucleoplasm]

input

Latent Transcriptinally Repressed HCMV Genome

Cross References

RefSeq

NP_001120700.1, NP_006798.1

OpenTargets

ENSG00000108468

HPA

ENSG00000108468-CBX1

GeneCards

P83916

Ensembl

ENST00000393408, ENSP00000225603, ENST00000225603, ENSG00000108468, ENSP00000377060

ZINC target

P83916

PRO

P83916

PDB

6D07, 5T1G, 3F2U, 2FMM, 3Q6S, 6D08

Interactors (25)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P68431 H3C1	59	2xAcK-HIST1H3A [nucleoplasm] (R-HSA-427507) HIST1H3A [extracellular region] (R-HSA-977570) Ack-Me3K5-HIST1H3A [nucleoplasm] (R-HSA-4551293) AcK-Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4551291) AcK-Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4551292) AcK19-HIST1H3A [nucleoplasm] (R-HSA-4568761) AcK5-HIST1H3A [nucleoplasm] (R-HSA-4568751) AcK24-HIST1H3A [nucleoplasm] (R-HSA-4568754) AcK15-HIST1H3A [nucleoplasm] (R-HSA-4568743) Ack15-HIST1H3A [nucleoplasm] (R-HSA-4549217) Me2aR27-HIST1H3A [nucleoplasm] (R-HSA-5229052) MeR27-HIST1H3A [nucleoplasm] (R-HSA-5229050) Me2aR18-HIST1H3A [nucleoplasm] (R-HSA-5229062) Me2sR9-HIST1H3A [nucleoplasm] (R-HSA-5211328) Me2sR3-HIST1H3A [nucleoplasm] (R-HSA-5218935) AcK9,14-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8870893) AcK14,18,79-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871271) AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871306) AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871294) AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8865596) AcK14,18-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871295) AcK14,18,79-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871288) AcK14,18-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871299) AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871286) Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4754188) Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4754169) Me2K28-HIST1H3A [nucleoplasm] (R-HSA-4754193) MeK37-HIST1H3A [nucleoplasm] (R-HSA-4722135) MeK80-HIST1H3A [nucleoplasm] (R-HSA-5649791) Me3K80-HIST1H3A [nucleoplasm] (R-HSA-5649795) Me2K80-HIST1H3A [nucleoplasm] (R-HSA-5649768) Me3K37-HIST1H3A [nucleoplasm] (R-HSA-5638160) Me2K37-HIST1H3A [nucleoplasm] (R-HSA-4722125) MeK10-HIST1H3A [nucleoplasm] (R-HSA-212105) MeK28-HIST1H3A [nucleoplasm] (R-HSA-5638327) MeK-10-HIST1H3A [cytosol] (R-HSA-8943830) HIST1H3A [cytosol] (R-HSA-8943829) Me2aR3-HIST1H3A [nucleoplasm] (R-HSA-5244526) MeK5-HIST1H3A [nucleoplasm] (R-HSA-4687016) Cit27-HIST1H3A [nucleoplasm] (R-HSA-5246532) Cit3-HIST1H3A [nucleoplasm] (R-HSA-5246544) Cit9-HIST1H3A [nucleoplasm] (R-HSA-5246530) Cit18-HIST1H3A [nucleoplasm] (R-HSA-5246534) MeR18-HIST1H3A [nucleoplasm] (R-HSA-5229059) MeR3-HIST1H3A [nucleoplasm] (R-HSA-5244529) MeR27-HIST1H3A [nucleoplasm] (R-HSA-5244801) MeR9-HIST1H3A [nucleoplasm] (R-HSA-5244806) Ack10-HIST1H3A [nucleoplasm] (R-HSA-4568939) Me2K5,Me2aR3-HIST1H3A [nucleoplasm] (R-HSA-8936572) p-T12-HIST1H3A [nucleoplasm] (R-HSA-5625872) p-T12,MeK-10-HIST1H3A [nucleoplasm] (R-HSA-5625859) Me3K-10-HIST1H3A [nucleoplasm] (R-HSA-427734) p-T12, Me2K-10-HIST1H3A [nucleoplasm] (R-HSA-5625790) p-T12, Me3K-10-HIST1H3A [nucleoplasm] (R-HSA-5625757) Me2K10-HIST1H3A [nucleoplasm] (R-HSA-427378) Me3K5-HIST1H3A [nucleoplasm] (R-HSA-1214186) HIST1H3A [nucleoplasm] (R-HSA-212070) Me3K-28-HIST1H3A [nucleoplasm] (R-HSA-212220) Me2K5-HIST1H3A [nucleoplasm] (R-HSA-1214170)	0.835	13
UniProt:O43463 SUV39H1	1	SUV39H1 [nucleoplasm] (R-HSA-427517)	0.666	4
UniProt:Q8ND82 Z280C			0.666	4
UniProt:P45973 CBX5	2	SUMO1-K84,K-CBX5 [nucleoplasm] (R-HSA-4615849) CBX5 [nucleoplasm] (R-HSA-994093)	0.643	4
UniProt:Q14839 CHD4	1	CHD4 [nucleoplasm] (R-HSA-3702078)	0.643	4
UniProt:Q7Z3K3 POGZ			0.643	3
UniProt:Q96JM3 CHAP1			0.643	3
UniProt:Q6IQ32 ADNP2			0.623	3
UniProt:Q9H2P0 ADNP			0.623	3
UniProt:Q7Z589 EMSY			0.618	3
UniProt:Q9D752	1	Mad2l2 [nucleoplasm] (R-MMU-59092)	0.564	2
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.556	3
UniProt:Q8TBE0 BAHD1			0.556	3
IntAct:EBI-22329726 CCSB ORF ID			0.556	3
UniProt:P23497-2 SP100			0.556	3
UniProt:Q5FBB7 SGO1	1	SGOL1 [cytosol] (R-HSA-376227)	0.544	2
UniProt:Q13263 TRIM28	2	TRIM28 [nucleoplasm] (R-HSA-974998) SUMO1-K554,575,676,750,779,804-TRIM28 [nucleoplasm] (R-HSA-3782600)	0.527	2
UniProt:Q9BWN1 PRR14			0.527	2
UniProt:Q13112 CAF1B			0.527	2
UniProt:Q13111 CAF1A			0.527	2
UniProt:Q9BYE7 PCGF6	1	PCGF6 [nucleoplasm] (R-HSA-8953572)	0.527	3
UniProt:Q12873 CHD3	2	SUMO1-K1971-CHD3 [nucleoplasm] (R-HSA-8956372) CHD3 [nucleoplasm] (R-HSA-4657012)	0.527	3
UniProt:Q13185 CBX3	1	CBX3 [nucleoplasm] (R-HSA-427386)	0.527	4
UniProt:P10588 NR2F6	1	NR2F6 [nucleoplasm] (R-HSA-376279)	0.524	2
UniProt:Q9UHL9 GT2D1			0.463	2