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LHFPL5 [plasma membrane]
Stable Identifier
R-HSA-9658860
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
fullName evidence="9"LHFPL tetraspan subfamily member 5 protein, LHPL5_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell (Homo sapiens)
MET channel [plasma membrane] (Homo sapiens)
LHFPL5 [plasma membrane] (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (IHC) [plasma membrane] (Homo sapiens)
MET channel [plasma membrane] (Homo sapiens)
LHFPL5 [plasma membrane] (Homo sapiens)
Sensory processing of sound by outer hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell (Homo sapiens)
MET channel [plasma membrane] (Homo sapiens)
LHFPL5 [plasma membrane] (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (OHC) [plasma membrane] (Homo sapiens)
MET channel [plasma membrane] (Homo sapiens)
LHFPL5 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TAF8 LHFPL5
Gene Names
LHFPL5, TMHS
Chain
chain:1-219
Reference Genes
BioGPS Gene:222662 LHFPL5
COSMIC (genes):LHFPL5 LHFPL5
CTD Gene:222662 LHFPL5
dbSNP Gene:222662 LHFPL5
ENSEMBL:ENSG00000197753 LHFPL5
HGNC:21253 LHFPL5
Monarch:222662 LHFPL5
NCBI Gene:222662 LHFPL5
OMIM:609427 LHFPL5
UCSC:Q8TAF8 LHFPL5
Reference Transcript
RefSeq:NM_182548.3 LHFPL5
Other Identifiers
11737550_at
1555043_PM_at
1555043_at
17007876
222662
2904837
2904838
2904839
2904841
2904842
2904845
2904849
2904853
3836648
8118995
A_14_P104769
A_32_P494620
GE571044
GO:0005515
GO:0005886
GO:0006811
GO:0007605
GO:0016020
GO:0016324
GO:0032421
GO:0032426
GO:0050877
GO:0050910
GO:0050974
GO:0060088
HMNXSV003053994
Hs2.367947.1.S1_3p_at
ILMN_1788291
PH_hs_0017533
TC06000522.hg
Participates
as a component of
MET channel [plasma membrane] (Homo sapiens)
Cross References
ENSEMBL
ENST00000651676
,
ENSP00000498322
,
ENST00000360215
,
ENST00000651132
,
ENSP00000353346
,
ENSP00000498699
OpenTargets
ENSG00000197753
HPA
ENSG00000197753-LHFPL5
PRO
Q8TAF8
Pharos - Targets
Q8TAF8
Orphanet
LHFPL5
Interactors (18)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NPL8 TIMMDC1
1
TIMMDC1 [mitochondrial inner membrane]
(R-HSA-5689720)
0.556
3
UniProt:Q969S0 SLC35B4
1
SLC35B4 [Golgi membrane]
(R-HSA-742365)
0.556
3
UniProt:O00501 CLDN5
2
CLDN5 [cell junction]
(R-HSA-421264)
CLDN5 [plasma membrane]
(R-HSA-419991)
0.556
3
UniProt:Q9Y6X1 SERP1
2
SERP1 [endoplasmic reticulum membrane]
(R-HSA-381045)
SERP1 [cytosol]
(R-HSA-5250574)
0.556
3
UniProt:Q96BA8 CREB3L1
7
CREB3L1 [Golgi membrane]
(R-HSA-8874155)
CREB3L1(427-519) [Golgi membrane]
(R-HSA-8874139)
CREB3L1(1-426) [Golgi membrane]
(R-HSA-8874153)
CREB3L1 [endoplasmic reticulum membrane]
(R-HSA-8874157)
CREB3L1(1-375) [cytosol]
(R-HSA-8874215)
CREB3L1(376-426) [Golgi membrane]
(R-HSA-8874213)
CREB3L1(1-375) [nucleoplasm]
(R-HSA-8874222)
0.556
3
UniProt:O15552 FFAR2
1
FFAR2 [plasma membrane]
(R-HSA-443944)
0.556
3
UniProt:Q9Y5Z9 UBIAD1
1
UBIAD1 [endoplasmic reticulum membrane]
(R-HSA-2980965)
0.556
3
UniProt:O75396 SEC22B
6
SEC22B [endoplasmic reticulum membrane]
(R-HSA-5688150)
SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688566)
SEC22B [ER to Golgi transport vesicle membrane]
(R-HSA-5688565)
SEC22B [phagocytic vesicle membrane]
(R-HSA-8863938)
SEC22B [transport vesicle]
(R-HSA-6810994)
SEC22B [Golgi membrane]
(R-HSA-6810993)
0.556
3
UniProt:P78382 SLC35A1
2
SLC35A1 [Golgi membrane]
(R-HSA-727812)
SLC35A1 V93Cfs*17 [Golgi membrane]
(R-HSA-5651957)
0.556
3
UniProt:O95674 CDS2
1
CDS2 [mitochondrial inner membrane]
(R-HSA-1498755)
0.556
3
UniProt:Q15836 VAMP3
6
VAMP3 [recycling endosome membrane]
(R-HSA-2029063)
VAMP3 [phagocytic vesicle membrane]
(R-HSA-2029013)
VAMP3 [plasma membrane]
(R-HSA-8867599)
VAMP3 [trans-Golgi network membrane]
(R-HSA-6814624)
VAMP3 [transport vesicle]
(R-HSA-6814625)
VAMP3 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869130)
0.556
3
UniProt:Q8WVV5 BTN2A2
1
BTN2A2 [plasma membrane]
(R-HSA-8851047)
0.556
3
UniProt:O60883 GPR37L1
1
GPR37L1 [plasma membrane]
(R-HSA-5336178)
0.556
3
UniProt:O43561-2 LAT
2
p-5Y-LAT-2 [plasma membrane]
(R-HSA-2396597)
LAT-2 [plasma membrane]
(R-HSA-2396548)
0.556
3
UniProt:Q9H2K0 MTIF3
1
MTIF3 [mitochondrial matrix]
(R-HSA-5368284)
0.556
3
UniProt:P29033 GJB2
3
GJB2 [endoplasmic reticulum-Golgi intermediate compartment]
(R-HSA-190614)
GJB2 [endoplasmic reticulum membrane]
(R-HSA-1629779)
GJB2 [plasma membrane]
(R-HSA-53211)
0.556
3
UniProt:P41732 TSPAN7
1
TSPAN7 [plasma membrane]
(R-HSA-400337)
0.556
3
UniProt:P21854 CD72
1
CD72 [plasma membrane]
(R-HSA-198121)
0.556
3
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