ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region

Stable Identifier
R-HSA-9661417
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Bilirubin glucuronides (BMG and BDG) are transported out of hepatocytes through their apical surfaces into the bile ducts, mainly by ABCC2 (MRP2) but also by the tetrameric efflux pump ATP-binding cassette sub-family G member 2 (ABCG2) (Xu et al. 2004).

Literature References
PubMed ID Title Journal Year
15001581 Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2

Xu, J, Liu, Y, Yang, Y, Bates, S, Zhang, JT

J. Biol. Chem. 2004
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
bilirubin transmembrane transporter activity of ABCG2 tetramer [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created