Reactome | p-T564-RDX [cytosol]

p-T564-RDX [cytosol]

Stable Identifier

R-HSA-9662922

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Radixin, RADI_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P35241 RDX

Gene Names

RDX

Chain

chain:1-583

Reference Genes

BioGPS Gene:5962 RDX

COSMIC (genes):RDX RDX

CTD Gene:5962 RDX

dbSNP Gene:5962 RDX

ENSEMBL:ENSG00000137710 RDX

HGNC:9944 RDX

KEGG:hsa:5962 RDX

Monarch:5962 RDX

NCBI Entrez Gene:5962 RDX

OMIM:179410 RDX

UCSC:P35241 RDX

Reference Transcript

Other Identifiers

11717524_s_at

11717525_s_at

11717526_a_at

11717527_a_at

11748967_a_at

11748968_x_at

11759725_a_at

11761819_a_at

16744174

204969_PM_s_at

204969_s_at

212397_PM_at

212397_at

212398_PM_at

212398_at

244739_PM_at

244739_at

3360106

3390529

3390545

3390552

3390555

3390556

3390557

3390563

3390570

3390571

3390572

3390573

3390574

3390575

3390576

3390577

3390579

3390581

3390582

3390584

3390585

3390586

3390587

3390590

3390591

3390594

3390595

3390597

3390598

3390600

3390601

3390602

3390604

3390605

3390608

3390612

34886_at

34887_at

3972499

4003523

56730_at

5962

7951554

86296_at

A_19_P00317164

A_19_P00800682

A_23_P203023

A_33_P3423121

GE491397

GE81208

GO:0001726

GO:0003723

GO:0003779

GO:0005515

GO:0005615

GO:0005737

GO:0005856

GO:0005886

GO:0005902

GO:0005912

GO:0005925

GO:0008092

GO:0008360

GO:0010628

GO:0010737

GO:0016020

GO:0016324

GO:0019904

GO:0030027

GO:0030033

GO:0030175

GO:0030315

GO:0030496

GO:0030864

GO:0032154

GO:0032420

GO:0032487

GO:0036120

GO:0042995

GO:0045176

GO:0045177

GO:0045184

GO:0045296

GO:0045732

GO:0048856

GO:0050839

GO:0051016

GO:0051018

GO:0051117

GO:0051286

GO:0051693

GO:0061028

GO:0061951

GO:0070062

GO:0071944

GO:0072659

GO:0097067

GO:0120044

GO:0150054

GO:1900087

GO:1902115

GO:1902966

GO:1903391

GO:2000643

HMNXSV003003266

HMNXSV003047070

Hs.263671.0.A1_3p_at

Hs.263671.0.A2_3p_at

Hs.96297.0.A1_3p_at

ILMN_1708611

L02320_at

PH_hs_0029542

TC11002274.hg

TC11003334.hg

g4506466_3p_s_at

Participates

as a component of

Stereocilium shaft [cytosol] (Homo sapiens)

Other forms of this molecule

RDX [cytosol]

Modified Residues

Name

O-phospho-L-threonine at 564

Coordinate

564

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

XP_047283346.1, NP_001247422.1, NP_001247425.1, NP_001247423.1, NP_001247424.1, NP_002897.1, NP_001247421.1, XP_054225575.1

OpenTargets

ENSG00000137710

ENSEMBL

ENSP00000433580, ENSP00000445826, ENST00000530301, ENST00000528900, ENST00000530749, ENST00000544551, ENST00000528498, ENSG00000137710, ENSP00000437301, ENST00000645495, ENSP00000496503, ENSP00000496414, ENSP00000432112, ENSP00000436277, ENST00000647231

HPA

ENSG00000137710-RDX

GeneCards

RDX

PRO

P35241

Pharos - Targets

P35241

Orphanet

RDX

GlyGen

P35241

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P15311 EZR	3	p-Y146,Y354-EZR [cytosol] (R-HSA-374572) p-T567-EZR [cytosol] (R-HSA-374559) EZR [cytosol] (R-HSA-9020826)	0.856	11
UniProt:P26038 MSN	4	MSN [cytosol] (R-HSA-437350) MSN(2-448)-ALK(1064-1620) fusion [cytosol] (R-HSA-9711966) MSN(2-448)-p-7Y-ALK(1064-1620) fusion [cytosol] (R-HSA-9711971) p-T558-MSN [cytosol] (R-HSA-9663005)	0.643	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	10
UniProt:P52565 ARHGDIA	1	ARHGDIA [cytosol] (R-HSA-194478)	0.544	2
UniProt:P10911 MCF2	1	MCF2 [cytosol] (R-HSA-3006639)	0.544	2
UniProt:Q15031 LARS2	1	LARS2(1-?) [mitochondrial matrix] (R-HSA-379635)	0.527	2
UniProt:P35240 NF2	1	NF2 [plasma membrane] (R-HSA-5669168)	0.527	2