Reactome | NBR1 [cytosol]

NBR1 [cytosol]

Stable Identifier

R-HSA-9665180

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Next to BRCA1 gene 1 protein

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q14596 NBR1

Gene Names

NBR1, 1A13B, KIAA0049, M17S2, MIG19

Chain

chain:1-966

Reference Genes

BioGPS Gene:4077 NBR1

COSMIC (genes):NBR1 NBR1

CTD Gene:4077 NBR1

dbSNP Gene:4077 NBR1

ENSEMBL:ENSG00000188554 NBR1

HGNC:6746 NBR1

KEGG:hsa:4077 NBR1

Monarch:4077 NBR1

NCBI Gene:4077 NBR1

OMIM:166945 NBR1

UCSC:Q14596 NBR1

Reference Transcript

Other Identifiers

11735119_x_at

11738519_x_at

11742199_s_at

11747268_s_at

11752179_s_at

11760863_at

1568856_PM_at

1568856_at

1568857_PM_a_at

1568857_a_at

16834578

201383_PM_s_at

201383_s_at

201384_PM_s_at

201384_s_at

33444_at

3722420

3722421

3722422

3722423

3722424

3722430

3722431

3722432

3722433

3722434

3722435

3722436

3722437

3722438

3722439

3722440

3722441

3722442

3722443

3722444

3722445

3722446

3722447

3722448

3722449

3722450

3722451

3722452

3722456

3722457

3722458

3722462

3722465

3722467

3722470

3722471

3722472

3722473

3722474

3722475

3722480

3722481

3722482

3722483

3722484

4039546

4039547

4039548

4039549

4039550

4039551

4039552

4039554

4039555

4039556

4039557

4039560

4039563

4039565

4039567

4039568

4039569

4039570

4039571

4039572

4039573

4039574

4039575

4077

50416_at

8007471

A_23_P207399

A_33_P3305770

D30756_at

GE61737

GE781601

GO:0000407

GO:0005515

GO:0005654

GO:0005737

GO:0005739

GO:0005758

GO:0005764

GO:0005768

GO:0005770

GO:0005773

GO:0005776

GO:0005778

GO:0005829

GO:0006914

GO:0008270

GO:0016020

GO:0016236

GO:0016604

GO:0030500

GO:0031410

GO:0031430

GO:0032872

GO:0043130

GO:0043226

GO:0043231

GO:0043235

GO:0045668

GO:0046872

GO:0051019

HMNXSV003037718

HMNXSV003045027

Hs.277721.0.A1_3p_a_at

Hs2.135500.1.A1_3p_at

Hs2.135500.1.A1_3p_s_at

ILMN_1672538

ILMN_1735333

ILMN_1799628

ILMN_1806474

ILMN_1807413

PH_hs_0018086

PH_hs_0027847

PH_hs_0028525

TC17000548.hg

g5174504_3p_a_at

Participates

as an input of

NBR1 translocates from cytosol to perixosomal membrane (Homo sapiens)

Other forms of this molecule

NBR1 [peroxisomal membrane]

Cross References

RefSeq

NP_001278501.1, XP_011523115.1, NP_114068.1, XP_016880131.1, NP_005890.2, NP_001278500.1

OpenTargets

ENSG00000188554

ENSEMBL

ENSP00000467816, ENSP00000343479, ENST00000341165, ENSP00000466667, ENST00000590996, ENST00000589872

HPA

ENSG00000188554-NBR1

PRO

Q14596

Pharos - Targets

Q14596

GlyGen

Q14596

PDB

2MGW, 2CP8, 2L8J, 2BKF, 4OLE, 2MJ5, 1WJ6, 2G4S

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49840 GSK3A	3	GSK3A [cytosol] (R-HSA-198326) p-S21-GSK3A [cytosol] (R-HSA-198352) p-Y279-GSK3A [cytosol] (R-HSA-9635490)	0.844	7
UniProt:Q13501 SQSTM1	7	SQSTM1 [cytosol] (R-HSA-193937) SQSTM1 [nucleoplasm] (R-HSA-210961) ub K420 p-S349 SQSTM1 [cytosol] (R-HSA-9766536) p-S349 SQSTM1 [cytosol] (R-HSA-9766524) K7 ub-SQSTM1 [cytosol] (R-HSA-9759088) SQSTM1(2-251)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711954) SQSTM1(2-251)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711967)	0.775	7
UniProt:O95166 GABARAP	3	GABARAP [cytosol] (R-HSA-975521) GABARAP(1-117) [cytosol] (R-HSA-5682696) GABARAP [autophagosome membrane] (R-HSA-5683634)	0.775	6
UniProt:Q9GZQ8 MAP1LC3B	3	MAP1LC3B [cytosol] (R-HSA-5205651) MAP1LC3B(2-121) [cytosol] (R-HSA-5682674) MAP1LC3B [autophagosome membrane] (R-HSA-5683641)	0.766	9
UniProt:P60520 GABARAPL2	3	GABARAPL2 [cytosol] (R-HSA-5671758) GABARAPL2(1-117) [cytosol] (R-HSA-5682641) GABARAPL2 [autophagosome membrane] (R-HSA-5683633)	0.725	11
UniProt:Q9H0R8 GABARAPL1	3	GABARAPL1 [cytosol] (R-HSA-5671757) GABARAPL1(1-117) [cytosol] (R-HSA-5682659) GABARAPL1 [autophagosome membrane] (R-HSA-5683637)	0.704	4
UniProt:Q9H492 MAP1LC3A	3	MAP1LC3A [cytosol] (R-HSA-5205676) MAP1LC3A(1-121) [cytosol] (R-HSA-5682681) MAP1LC3A [autophagosome membrane] (R-HSA-5683640)	0.684	5
UniProt:Q9BXW4 MAP1LC3C	3	MAP1LC3C [cytosol] (R-HSA-5679223) MAP1LC3C(1-147) [cytosol] (R-HSA-5682653) MAP1LC3C [autophagosome membrane] (R-HSA-5683638)	0.676	3
UniProt:P49841 GSK3B	4	GSK3B [cytosol] (R-HSA-2997551) p-S9-GSK3B [cytosol] (R-HSA-3149577) GSK3B [nucleoplasm] (R-HSA-2022823) GSK3B del304-316 [cytosol] (R-HSA-5339682)	0.646	4
UniProt:P0CG48 UBC	20	UBC(381-456) [endocytic vesicle membrane] (R-HSA-939218) UBC(533-608) [endocytic vesicle membrane] (R-HSA-939220) UBC(609-684) [endocytic vesicle membrane] (R-HSA-939223) UBC(457-532) [endocytic vesicle membrane] (R-HSA-939195) UBC(153-228) [endocytic vesicle membrane] (R-HSA-939194) UBC(305-380) [endocytic vesicle membrane] (R-HSA-939228) UBC(229-304) [endocytic vesicle membrane] (R-HSA-939177) UBC(77-152) [endocytic vesicle membrane] (R-HSA-939210) UBC(1-76) [endocytic vesicle membrane] (R-HSA-939245) Ub-565-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783166) Ub-337-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783121) Ub-185-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783154) Ub-261-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783028) Ub-413-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783061) Ub-109-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783158) Ub-641-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783182) Ub-33-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783073) Ub-489-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783078) Ub-291-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783193) Ub-595-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783130)	0.636	3
UniProt:P38182	12	ATG8 [cytosol] (R-SCE-5205651) ATG8 [cytosol] (R-SCE-5205676) ATG8 [cytosol] (R-SCE-975521) ATG8 [cytosol] (R-SCE-5679223) ATG8 [cytosol] (R-SCE-5682696) ATG8 [cytosol] (R-SCE-5682674) ATG8 [cytosol] (R-SCE-5682653) ATG8 [cytosol] (R-SCE-5682681) ATG8 [autophagosome membrane] (R-SCE-5683634) ATG8 [autophagosome membrane] (R-SCE-5683638) ATG8 [autophagosome membrane] (R-SCE-5683640) ATG8 [autophagosome membrane] (R-SCE-5683641)	0.635	7
UniProt:Q9H2B2 SYT4			0.556	3
UniProt:P40818 USP8	2	p-T945-USP8 [cytosol] (R-HSA-1358714) USP8 [cytosol] (R-HSA-917720)	0.543	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.463	3
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.462	2

Cite Us!