Reactome | p-PEX5 [peroxisomal membrane]

p-PEX5 [peroxisomal membrane]

Stable Identifier

R-HSA-9665182

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

peroxisomal membrane

Synonyms

p-Peroxisomal targeting signal 1 receptor, p-PEX5_HUMAN

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External Reference Information

External Reference

UniProt:P50542 PEX5

Gene Names

PEX5, PXR1

Chain

chain:1-639

Reference Genes

COSMIC (genes):PEX5 PEX5

dbSNP Gene:5830 PEX5

ENSEMBL:ENSG00000139197 PEX5

Participates

as a component of

ATM:p-PEX5 [peroxisomal membrane] (Homo sapiens)

Other forms of this molecule

Ub-p-PEX5 [peroxisomal membrane]

PEX5 [peroxisomal membrane]

PEX5 [cytosol]

Inferred To

phospho-Pex5 [peroxisomal membrane] (Drosophila melanogaster)

phospho-Pex5 [peroxisomal membrane] (Mus musculus)

phospho-Pex5 [peroxisomal membrane] (Rattus norvegicus)

phospho-pex5 [peroxisomal membrane] (Dictyostelium discoideum)

phospho-pex5 [peroxisomal membrane] (Schizosaccharomyces pombe)

phospho-PEX5 [peroxisomal membrane] (Bos taurus)

phospho-PEX5 [peroxisomal membrane] (Canis familiaris)

phospho-PEX5 [peroxisomal membrane] (Saccharomyces cerevisiae)

phospho-PEX5 [peroxisomal membrane] (Sus scrofa)

phospho-p-PEX5 [peroxisomal membrane] (Gallus gallus)

Modified Residues

Name

O-phospho-L-serine at 141

Coordinate

141

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75381 PEX14	2	PEX14 [cytosol] (R-HSA-9603806) PEX14 [peroxisomal membrane] (R-HSA-9033101)	0.807	13
UniProt:O00623 PEX12	2	PEX12 [cytosol] (R-HSA-9603782) PEX12 [peroxisomal membrane] (R-HSA-8953911)	0.683	4
UniProt:P07195 LDHB	1	LDHB [cytosol] (R-HSA-70503)	0.556	3
UniProt:EP400NL H9KV84			0.556	3
UniProt:Q9NZ81 PRR13			0.556	3
UniProt:Q49A88 CCD14			0.556	3
UniProt:Q6NSB6 Q6NSB6			0.556	3
UniProt:A8K3Q9 A8K3Q9			0.556	3
UniProt:Q8N5N8 Q8N5N8			0.556	3
UniProt:Q75MR5 Q75MR5			0.556	3
UniProt:Q6IPH7 Q6IPH7			0.556	3
UniProt:Q68DY9 ZNF772	1	ZNF772 [nucleoplasm] (R-HSA-3110231)	0.556	3
UniProt:P06703 S10A6			0.556	3
UniProt:Q6IMN6 CAPR2			0.556	3
UniProt:O14734 ACOT8	2	ACOT8 [cytosol] (R-HSA-9033134) ACOT8 [peroxisomal matrix] (R-HSA-193426)	0.556	3
UniProt:Q8WTR4 GDPD5	1	GDPD5 [endoplasmic reticulum membrane] (R-HSA-6814136)	0.556	3
UniProt:Q9BSI4 TINF2	1	TINF2 [nucleoplasm] (R-HSA-174883)	0.508	2

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