Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
SMAD3 E246* [cytosol]
Stable Identifier
R-HSA-9668776
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SMAD3 E246TER, SMAD3 Glu246*, SMAD3 Glu246TER
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by TGF-beta Receptor Complex in Cancer (Homo sapiens)
Loss of Function of SMAD2/3 in Cancer (Homo sapiens)
SMAD2/3 Phosphorylation Motif Mutants in Cancer (Homo sapiens)
Activated TGFBR1 cannot phosphorylate SMAD2 and SMAD3 Phosphorylation Motif Mutants (Homo sapiens)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 Phosphorylation Motif Mutants [early endosome membrane] (Homo sapiens)
SMAD2/3 Phosphorylation Motif Mutants [cytosol] (Homo sapiens)
SMAD3 Phosphorylation Motif Mutants [cytosol] (Homo sapiens)
SMAD3 E246* [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P84022 SMAD3
Gene Names
SMAD3, MADH3
Chain
initiator methionine:1, chain:2-425
Reference Genes
BioGPS Gene:4088 SMAD3
COSMIC (genes):SMAD3 SMAD3
CTD Gene:4088 SMAD3
dbSNP Gene:4088 SMAD3
ENSEMBL:ENSG00000166949 SMAD3
HGNC:6769 SMAD3
KEGG Gene (Homo sapiens):4088 SMAD3
Monarch:4088 SMAD3
NCBI Gene:4088 SMAD3
OMIM:603109 SMAD3
UCSC:P84022 SMAD3
Reference Transcript
RefSeq:NM_005902.3 SMAD3
RefSeq:NM_001145103.1 SMAD3
RefSeq:NM_001145104.1 SMAD3
RefSeq:NM_001145102.1 SMAD3
Other Identifiers
0000380136
0005860086
11718265_a_at
11718266_s_at
11726549_a_at
11751185_a_at
11754091_s_at
1433_g_at
1454_at
1950_s_at
205396_at
205397_x_at
205398_s_at
218284_at
3598960
3598961
3598977
3598984
3598992
3598993
3598994
3598995
3598997
3598999
3599014
3599016
3599023
3599028
3599029
3599030
3599031
3599032
3599033
3599034
3599035
3599036
3599037
3599038
3599039
3599040
3599041
3599042
38944_at
4088
44841_at
44986_s_at
51059_at
58763_at
65983_at
7984364
A_14_P107358
A_23_P48936
GE56446
GE79350
GO:0000122
GO:0000228
GO:0000278
GO:0000790
GO:0000976
GO:0000977
GO:0000978
GO:0000981
GO:0000987
GO:0001102
GO:0001223
GO:0001228
GO:0001501
GO:0001649
GO:0001657
GO:0001666
GO:0001701
GO:0001707
GO:0001756
GO:0001889
GO:0001947
GO:0002076
GO:0002376
GO:0002520
GO:0003013
GO:0003674
GO:0003677
GO:0003682
GO:0003690
GO:0003700
GO:0005160
GO:0005515
GO:0005518
GO:0005575
GO:0005622
GO:0005634
GO:0005635
GO:0005637
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0005886
GO:0006355
GO:0006357
GO:0006464
GO:0006810
GO:0006913
GO:0006919
GO:0006950
GO:0006955
GO:0007010
GO:0007049
GO:0007050
GO:0007155
GO:0007165
GO:0007179
GO:0007183
GO:0007267
GO:0007369
GO:0007492
GO:0008013
GO:0008134
GO:0008150
GO:0008219
GO:0008270
GO:0008283
GO:0008285
GO:0009056
GO:0009058
GO:0009790
GO:0009880
GO:0010628
GO:0010694
GO:0010718
GO:0015031
GO:0016032
GO:0016202
GO:0016579
GO:0017015
GO:0017151
GO:0019899
GO:0019901
GO:0019902
GO:0022607
GO:0023019
GO:0030154
GO:0030198
GO:0030308
GO:0030325
GO:0030335
GO:0030501
GO:0030512
GO:0030878
GO:0031053
GO:0031490
GO:0031625
GO:0031962
GO:0032182
GO:0032332
GO:0032731
GO:0032909
GO:0032916
GO:0032924
GO:0032991
GO:0033689
GO:0034330
GO:0034641
GO:0035259
GO:0038092
GO:0040007
GO:0040011
GO:0042060
GO:0042110
GO:0042177
GO:0042307
GO:0042592
GO:0042802
GO:0042803
GO:0043066
GO:0043130
GO:0043167
GO:0043226
GO:0043235
GO:0043425
GO:0043565
GO:0044403
GO:0045216
GO:0045429
GO:0045599
GO:0045668
GO:0045893
GO:0045930
GO:0045944
GO:0046332
GO:0046872
GO:0048340
GO:0048589
GO:0048617
GO:0048646
GO:0048701
GO:0048856
GO:0048870
GO:0050678
GO:0050728
GO:0050776
GO:0050821
GO:0050927
GO:0051091
GO:0051098
GO:0051481
GO:0051496
GO:0051894
GO:0060039
GO:0060290
GO:0060395
GO:0061045
GO:0061767
GO:0065003
GO:0070306
GO:0070410
GO:0070412
GO:0071141
GO:0071144
GO:0071345
GO:0071560
GO:0090263
GO:0097191
GO:0097296
GO:1901203
GO:1902895
GO:1903243
Hs.211578.0.S3_3p_at
ILMN_1682738
PH_hs_0032513
PH_hs_0039929
TC15000622.hg
TC15002251.hg
U68019_at
g1673576_3p_s_at
g5174512_3p_s_at
g7661691_3p_at
Participant Of
hasCandidate
SMAD3 Phosphorylation Motif Mutants [cytosol]
Other forms of this molecule
Ub-SMAD3 [cytosol]
p-S423,S425-SMAD3 D258N [cytosol]
p-S423,S425-SMAD3 R268C [cytosol]
p-S423,S425-SMAD3 R268H [cytosol]
SMAD3 Q316* [cytosol]
SMAD3 Y384* [cytosol]
SMAD3 W326* [cytosol]
SMAD3 Q358* [cytosol]
SMAD3 Q322* [cytosol]
SMAD3 S425F [cytosol]
SMAD3 E383* [cytosol]
SMAD3 R368* [cytosol]
SMAD3 Y298* [cytosol]
SMAD3 S425C [cytosol]
2xADPRib-p-S423,S425-SMAD3 [nucleoplasm]
p-T179,S423,S425-SMAD3 [nucleoplasm]
SMAD3 [nucleoplasm]
SMAD3 [cytosol]
p-S423,S425-SMAD3 [nucleoplasm]
p-S423,S425-SMAD3 [cytosol]
Modified Residues
Name
L-glutamic acid 246 replaced with unknown
Coordinate
246
PsiMod
L-glutamic acid removal [MOD:01636]
A protein modification that effectively removes or replaces an L-glutamic acid.
Disease
Name
Identifier
Synonyms
large intestine cancer
5672
malignant Colorectal tumor, malignant neoplasm of large intestine, NOS, malignant tumor of large intestine (disorder), malignant neoplasm of colon with rectum, malignant neoplasm of large intestine NOS
cancer
162
malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
NP_001138575.1
,
NP_001138576.1
,
NP_001138574.1
,
NP_005893.1
COSMIC
COSM6023580
OpenTargets
ENSG00000166949
GeneCards
P84022
HPA
ENSG00000166949-SMAD3
Ensembl
ENSG00000166949
,
ENST00000327367
,
ENST00000540846
,
ENSP00000445348
,
ENSP00000401133
,
ENST00000439724
,
ENSP00000437757
,
ENSP00000332973
,
ENST00000537194
PRO
P84022
Orphanet
19833
PDB
5ODG
,
1MHD
,
2LB2
,
5OD6
,
1OZJ
,
2LAJ
,
5XOC
,
1U7F
,
1MK2
,
1MJS
Interactors (65)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13485 SMAD4
88
SMAD4 K428T [cytosol]
(R-HSA-3311004)
SMAD4 P356R [cytosol]
(R-HSA-3310988)
SMAD4 D351del [cytosol]
(R-HSA-3310974)
SMAD4 R361H [cytosol]
(R-HSA-3310984)
SMAD4 P356L [cytosol]
(R-HSA-3310987)
SMAD4 A406T [cytosol]
(R-HSA-3311003)
SMAD4 D351Y [cytosol]
(R-HSA-3310970)
SMAD4 D351H [cytosol]
(R-HSA-3310965)
SMAD4 R361C [cytosol]
(R-HSA-3310983)
SMAD4 D351G [cytosol]
(R-HSA-3310967)
SMAD4 R515T [cytosol]
(R-HSA-3311008)
SMAD4 G352* [cytosol]
(R-HSA-9678445)
SMAD4 S178* [cytosol]
(R-HSA-9675630)
SMAD4 G477* [cytosol]
(R-HSA-9678447)
SMAD4 G473* [cytosol]
(R-HSA-9678440)
SMAD4 S144* [cytosol]
(R-HSA-9675625)
SMAD4 E538* [cytosol]
(R-HSA-9675626)
SMAD4 E390* [cytosol]
(R-HSA-9675620)
SMAD4 S154* [cytosol]
(R-HSA-9675621)
SMAD4 E330* [cytosol]
(R-HSA-9675622)
SMAD4 E417* [cytosol]
(R-HSA-9675623)
SMAD4 Y195* [cytosol]
(R-HSA-9678462)
SMAD4 E108* [cytosol]
(R-HSA-9675640)
SMAD4 S343* [cytosol]
(R-HSA-9675641)
SMAD4 E520* [cytosol]
(R-HSA-9675636)
SMAD4 G510* [cytosol]
(R-HSA-9678452)
SMAD4 G358* [cytosol]
(R-HSA-9678453)
SMAD4 E175* [cytosol]
(R-HSA-9675637)
SMAD4 E307* [cytosol]
(R-HSA-9675639)
SMAD4 E53* [cytosol]
(R-HSA-9675633)
SMAD4 S171* [cytosol]
(R-HSA-9675634)
SMAD4 G30* [cytosol]
(R-HSA-9678450)
SMAD4 G168* [cytosol]
(R-HSA-9678451)
SMAD4 Q366* [cytosol]
(R-HSA-9675200)
SMAD4 R135* [cytosol]
(R-HSA-9675090)
SMAD4 L146* [cytosol]
(R-HSA-9678509)
SMAD4 L440* [cytosol]
(R-HSA-9678510)
SMAD4 Q183* [cytosol]
(R-HSA-9675176)
SMAD4 Q289* [cytosol]
(R-HSA-9675177)
SMAD4 Q248* [cytosol]
(R-HSA-9675178)
SMAD4 Q249* [cytosol]
(R-HSA-9675172)
SMAD4 Q256* [cytosol]
(R-HSA-9675173)
SMAD4 Q239* [cytosol]
(R-HSA-9675174)
SMAD4 Q245* [cytosol]
(R-HSA-9675175)
SMAD4 Q224* [cytosol]
(R-HSA-9675168)
SMAD4 W509* [cytosol]
(R-HSA-9678497)
SMAD4 Q311* [cytosol]
(R-HSA-9675169)
SMAD4 W398* [cytosol]
(R-HSA-9678498)
SMAD4 Q250* [cytosol]
(R-HSA-9675170)
SMAD4 Q410* [cytosol]
(R-HSA-9675196)
SMAD4 Q534* [cytosol]
(R-HSA-9675197)
SMAD4 Q83* [cytosol]
(R-HSA-9675199)
SMAD4 Q448* [cytosol]
(R-HSA-9675192)
SMAD4 K428R [cytosol]
(R-HSA-3311001)
SMAD4 Q455* [cytosol]
(R-HSA-9675193)
SMAD4 R445* [cytosol]
(R-HSA-9675065)
SMAD4 Q442* [cytosol]
(R-HSA-9675194)
SMAD4 Q516* [cytosol]
(R-HSA-9675195)
SMAD4 C443* [cytosol]
(R-HSA-9678523)
SMAD4 Q334* [cytosol]
(R-HSA-9675191)
SMAD4 R361G [cytosol]
(R-HSA-3310993)
SMAD4 L172* [cytosol]
(R-HSA-9678514)
SMAD4 K122* [cytosol]
(R-HSA-9678515)
SMAD4 R361S [cytosol]
(R-HSA-3310994)
SMAD4 Y430* [cytosol]
(R-HSA-9678476)
SMAD4 Y260* [cytosol]
(R-HSA-9678477)
SMAD4 Y95* [cytosol]
(R-HSA-9678478)
SMAD4 Y322* [cytosol]
(R-HSA-9678479)
SMAD4 E321* [cytosol]
(R-HSA-9675658)
SMAD4 Y412* [cytosol]
(R-HSA-9678469)
SMAD4 R515* [cytosol]
(R-HSA-3311012)
SMAD4 Y328* [cytosol]
(R-HSA-9678470)
SMAD4 E33* [cytosol]
(R-HSA-9675654)
SMAD4 Y513* [cytosol]
(R-HSA-9678471)
SMAD4 E526* [cytosol]
(R-HSA-9675648)
SMAD4 S138* [cytosol]
(R-HSA-9675649)
SMAD4 Y276* [cytosol]
(R-HSA-9678466)
SMAD4 E205* [cytosol]
(R-HSA-9675650)
SMAD4 E49* [cytosol]
(R-HSA-9675651)
SMAD4 W101* [cytosol]
(R-HSA-9678492)
SMAD4 W268* [cytosol]
(R-HSA-9678494)
SMAD4 [nucleoplasm]
(R-HSA-177103)
SMAD4 [cytosol]
(R-HSA-170862)
RibC-SMAD4 [nucleoplasm]
(R-HSA-2187323)
SMAD4 W524* [cytosol]
(R-HSA-9678491)
SMAD4 W302* [cytosol]
(R-HSA-9678490)
SMAD4 S242* [cytosol]
(R-HSA-9675167)
SMAD4 Q116* [cytosol]
(R-HSA-9675166)
0.979
33
UniProt:P12755 SKI
1
SKI [nucleoplasm]
(R-HSA-173473)
0.842
11
UniProt:Q9H2G9 BLZF1
1
BLZF1 [Golgi membrane]
(R-HSA-2422372)
0.805
9
UniProt:Q9H0M0 WWP1
1
WWP1 [cytosol]
(R-HSA-976037)
0.805
9
UniProt:Q9HAU4 SMURF2
2
SMURF2 [nucleoplasm]
(R-HSA-178202)
SMURF2 [cytosol]
(R-HSA-173537)
0.799
8
UniProt:O00308 WWP2
1
WWP2 [cytosol]
(R-HSA-6807279)
0.779
7
UniProt:O95405 ZFYVE9
0.764
5
UniProt:P50222 MEOX2
0.718
6
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.69
5
UniProt:O75593 FOXH1
1
FOXH1 [nucleoplasm]
(R-HSA-1225914)
0.675
4
UniProt:O43524 FOXO3
9
p-S215 FOXO3 [cytosol]
(R-HSA-5687014)
p-S215 FOXO3 [nucleoplasm]
(R-HSA-5687010)
FOXO3 [cytosol]
(R-HSA-5687032)
p-S43,S173,S294,S325-FOXO3 [nucleoplasm]
(R-HSA-8870627)
p-S43,S173,S294,S325-FOXO3 [cytosol]
(R-HSA-8870560)
Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm]
(R-HSA-9620514)
FOXO3 [nucleoplasm]
(R-HSA-199305)
p-T32,S253,S315-FOXO3 [nucleoplasm]
(R-HSA-199289)
p-T32,S253,S315-FOXO3 [cytosol]
(R-HSA-9614413)
0.667
5
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.666
4
UniProt:P84022 SMAD3
21
p-S423,S425-SMAD3 D258N [cytosol]
(R-HSA-3315470)
Ub-SMAD3 [cytosol]
(R-HSA-6782830)
p-S423,S425-SMAD3 R268C [cytosol]
(R-HSA-3315075)
p-S423,S425-SMAD3 R268H [cytosol]
(R-HSA-3315080)
SMAD3 Q316* [cytosol]
(R-HSA-9668765)
SMAD3 Y384* [cytosol]
(R-HSA-9668782)
SMAD3 W326* [cytosol]
(R-HSA-9668766)
SMAD3 E246* [cytosol]
(R-HSA-9668776)
SMAD3 Q358* [cytosol]
(R-HSA-9668772)
SMAD3 Q322* [cytosol]
(R-HSA-9668773)
SMAD3 S425F [cytosol]
(R-HSA-8944158)
SMAD3 E383* [cytosol]
(R-HSA-9668775)
SMAD3 R368* [cytosol]
(R-HSA-9668768)
SMAD3 Y298* [cytosol]
(R-HSA-9668769)
SMAD3 S425C [cytosol]
(R-HSA-3308499)
2xADPRib-p-S423,S425-SMAD3 [nucleoplasm]
(R-HSA-2187326)
p-T179,S423,S425-SMAD3 [nucleoplasm]
(R-HSA-2176471)
SMAD3 [nucleoplasm]
(R-HSA-206150)
SMAD3 [cytosol]
(R-HSA-170855)
p-S423,S425-SMAD3 [nucleoplasm]
(R-HSA-177104)
p-S423,S425-SMAD3 [cytosol]
(R-HSA-171184)
0.656
3
UniProt:Q64729
3
Tgfbr1 [plasma membrane]
(R-MMU-170839)
Tgfbr1 [plasma membrane]
(R-MMU-8869461)
phospho-Tgfbr1 [plasma membrane]
(R-MMU-170849)
0.576
6
UniProt:Q9BZ29 DOCK9
1
DOCK9 [cytosol]
(R-HSA-1012981)
0.576
3
UniProt:Q15796 SMAD2
27
p-S465,S467-SMAD2 P305L [cytosol]
(R-HSA-3315471)
Ub-SMAD2 [cytosol]
(R-HSA-6782774)
p-S465,S467-SMAD2 D300A [cytosol]
(R-HSA-3315064)
p-S465,S467-SMAD2 D300N [cytosol]
(R-HSA-3315066)
p-S465,S467-SMAD2 A354T [cytosol]
(R-HSA-3315474)
p-S465,S467-SMAD2 P305Q [cytosol]
(R-HSA-3315070)
p-S465,S467-SMAD2 D300V [cytosol]
(R-HSA-3315067)
SMAD2 S464* [cytosol]
(R-HSA-3304362)
SMAD2 W422* [cytosol]
(R-HSA-9668736)
SMAD2 S308* [cytosol]
(R-HSA-9668732)
SMAD2 R427* [cytosol]
(R-HSA-9668733)
SMAD2 W448* [cytosol]
(R-HSA-9668734)
SMAD2 S464L [cytosol]
(R-HSA-3304383)
SMAD2 C463* [cytosol]
(R-HSA-9668735)
SMAD2 R321* [cytosol]
(R-HSA-9668728)
SMAD2 S296* [cytosol]
(R-HSA-9668729)
SMAD2 S306* [cytosol]
(R-HSA-9668730)
SMAD2 Q455* [cytosol]
(R-HSA-9668731)
SMAD2 E439* [cytosol]
(R-HSA-9668724)
SMAD2 L315* [cytosol]
(R-HSA-9668725)
SMAD2 S467P [cytosol]
(R-HSA-3304375)
SMAD2 Q429* [cytosol]
(R-HSA-9668727)
p-T220,S465,S467-SMAD2 [nucleoplasm]
(R-HSA-3009189)
SMAD2 [nucleoplasm]
(R-HSA-3006352)
SMAD2 [cytosol]
(R-HSA-3006353)
p-S465,S467-SMAD2 [cytosol]
(R-HSA-3009186)
p-S465,S467-SMAD2 [nucleoplasm]
(R-HSA-3009185)
0.573
2
UniProt:Q99814 EPAS1
5
2xHP-EPAS1 [cytosol]
(R-HSA-1234149)
2xHP-EPAS1 [nucleoplasm]
(R-HSA-1234151)
HN-EPAS1 [cytosol]
(R-HSA-1234112)
EPAS1 [cytosol]
(R-HSA-1234119)
EPAS1 [nucleoplasm]
(R-HSA-452560)
0.573
2
UniProt:Q93009 USP7
2
USP7 [nucleoplasm]
(R-HSA-3215278)
USP7 [cytosol]
(R-HSA-8853511)
0.573
2
UniProt:Q9Y2U8 LEMD3
1
LEMD3 [nuclear envelope]
(R-HSA-2993886)
0.564
2
UniProt:P10070 GLI2
11
p8S-GLI2 [ciliary base]
(R-HSA-5610494)
p4S-GLI2 [ciliary base]
(R-HSA-5610487)
p11S-GLI2 [ciliary base]
(R-HSA-5610471)
ub-p11S-GLI2 [ciliary base]
(R-HSA-5610501)
GLI2 [ciliary tip]
(R-HSA-5610363)
GLI2 [ciliary base]
(R-HSA-5610361)
2p-GLI2 [nucleoplasm]
(R-HSA-5635055)
p-GLI2 [nucleoplasm]
(R-HSA-5635047)
p-GLI2 [ciliary tip]
(R-HSA-5635044)
GLI2 [cytosol]
(R-HSA-445451)
ub-2p-GLI2 [nucleoplasm]
(R-HSA-5635059)
0.558
4
UniProt:P46934-3 NEDD4
0.556
3
UniProt:Q06481-5 APLP2
0.556
3
UniProt:P48730-2 CSNK1D
0.556
3
UniProt:P29466-3 CASP1
0.556
3
UniProt:Q86YD7 F90A1
0.556
3
UniProt:P20618 PSMB1
5
PSMB1 [extracellular region]
(R-HSA-6806477)
PSMB1 [ficolin-1-rich granule lumen]
(R-HSA-6803340)
PSMB1 [secretory granule lumen]
(R-HSA-6803287)
PSMB1 [nucleoplasm]
(R-HSA-174347)
PSMB1 [cytosol]
(R-HSA-68738)
0.556
3
UniProt:Q8N684-3 CPSF7
0.556
3
UniProt:P0C264 SBK3
0.556
3
UniProt:E9PSE9 E9PSE9
0.556
3
UniProt:Q8IXK0-5 PHC2
0.556
3
UniProt:P27986-2 PIK3R1
0.556
3
IntAct:EBI-16439879 CCSB ORF ID
0.556
3
UniProt:Q08117-2 TLE5
0.556
3
UniProt:O43186 CRX
0.556
3
UniProt:Q15583 TGIF1
1
TGIF1 [nucleoplasm]
(R-HSA-2186594)
0.556
3
IntAct:EBI-11522976 CCDC33
0.556
3
UniProt:Q8WXH2 JPH3
0.556
3
UniProt:Q8WW24 TEKT4
0.556
3
UniProt:Q8N684 CPSF7
1
CPSF7 [nucleoplasm]
(R-HSA-72012)
0.556
3
UniProt:Q9UQM7 CAMK2A
6
p-T286-CAMK2A [cytosol]
(R-HSA-445368)
p-T286-CAMK2A [plasma membrane]
(R-HSA-432796)
CAMK2A [cytosol]
(R-HSA-4332329)
p-T286,T305,T306-CAMK2A [cytosol]
(R-HSA-4332334)
p-T286-CAMK2A [endocytic vesicle membrane]
(R-HSA-416999)
p-T286-CAMK2A [nucleoplasm]
(R-HSA-444797)
0.556
3
UniProt:Q8IXK0 PHC2
1
PHC2 [nucleoplasm]
(R-HSA-389112)
0.556
3
IntAct:EBI-10171584 80125
0.556
3
UniProt:Q6NX45 ZNF774
1
ZNF774 [nucleoplasm]
(R-HSA-3110232)
0.556
3
UniProt:P17612 PRKACA
3
PRKACA [cytosol]
(R-HSA-57844)
PRKACA [ciliary base]
(R-HSA-5610402)
PRKACA [nucleoplasm]
(R-HSA-111936)
0.556
3
UniProt:P05067 APP
20
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
UniProt:P15822 ZEP1
0.553
2
UniProt:O15397 IPO8
2
IPO8 [cytosol]
(R-HSA-5578740)
IPO8 [nucleoplasm]
(R-HSA-5578747)
0.544
2
UniProt:Q99836 MYD88
9
MyD88 E52del [cytosol]
(R-HSA-5602451)
MyD88 R196C [cytosol]
(R-HSA-5602329)
MYD88 [cytosol]
(R-HSA-193946)
MYD88 [plasma membrane]
(R-HSA-937017)
MYD88 [cytosol]
(R-HSA-166059)
MYD88 [endosome membrane]
(R-HSA-975123)
MyD88 E65del [cytosol]
(R-HSA-5602598)
MyD88 S34Y [cytosol]
(R-HSA-5602521)
MyD88 L93P [cytosol]
(R-HSA-5602612)
0.543
3
UniProt:Q13501 SQSTM1
2
SQSTM1 [cytosol]
(R-HSA-193937)
SQSTM1 [nucleoplasm]
(R-HSA-210961)
0.543
3
UniProt:P51141 Dvl1
4
Dvl1 [cytosol]
(R-MMU-1504179)
Dvl1 [cytosol]
(R-MMU-4641157)
phospho-Dvl1 [cytosol]
(R-MMU-201700)
phospho-Dvl1 [cytosol]
(R-MMU-3772396)
0.527
2
UniProt:Q9NYA4 MTMR4
2
MTMR4 [cytosol]
(R-HSA-1604658)
MTMR4 [early endosome membrane]
(R-HSA-2187404)
0.524
2
UniProt:P98082 DAB2
3
DAB2 [lysosomal membrane]
(R-HSA-2980807)
DAB2 [cytosol]
(R-HSA-8862456)
DAB2 [plasma membrane]
(R-HSA-2980808)
0.524
3
UniProt:Q9BYW2 SETD2
1
SETD2 [nucleoplasm]
(R-HSA-1183220)
0.508
2
UniProt:Q9H2X0 CHRD
0.508
2
UniProt:Q9BZL4 PP12C
0.508
2
UniProt:Q96EP0 RNF31
1
RNF31 [cytosol]
(R-HSA-5212660)
0.508
2
UniProt:Q9Y3Q8 T22D4
0.508
2
UniProt:Q16822 PCK2
1
PCK2 [mitochondrial matrix]
(R-HSA-372815)
0.508
2
UniProt:Q5D1E8 ZC12A
0.508
2
UniProt:P17844 DDX5
4
DDX5 [cytosol]
(R-HSA-9682643)
DDX5 [nucleoplasm]
(R-HSA-3900136)
SUMO2-K53-DDX5 [nucleoplasm]
(R-HSA-3900186)
SUMO1-K53-DDX5 [nucleoplasm]
(R-HSA-3900041)
0.499
2
UniProt:Q05066 SRY
1
SRY [nucleoplasm]
(R-HSA-5627706)
0.499
3
UniProt:P23142 FBLN1
1
FBLN1 [extracellular region]
(R-HSA-2161389)
0.488
2
UniProt:Q93062-3 RBPMS
0.488
2
UniProt:Q9NZH6 IL37
6
IL37(?-218) [extracellular region]
(R-HSA-9008607)
IL37(?-218) [nucleoplasm]
(R-HSA-9008702)
IL37 [extracellular region]
(R-HSA-8848334)
IL37(?-218) [cytosol]
(R-HSA-9008584)
IL37 [cytosol]
(R-HSA-9008596)
IL37(1-?) [cytosol]
(R-HSA-9008602)
0.463
2
UniProt:Q16665 HIF1A
7
2xHP-HIF1A [nucleoplasm]
(R-HSA-1234105)
2xHP-HIF1A [cytosol]
(R-HSA-1234131)
HN-HIF1A [cytosol]
(R-HSA-1234110)
p-Y565,S797-HIF1A [cytosol]
(R-HSA-9634700)
p-Y565-HIF1A [cytosol]
(R-HSA-8857584)
HIF1A [cytosol]
(R-HSA-1234102)
HIF1A [nucleoplasm]
(R-HSA-1234135)
0.463
6
© 2021
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text