Reactome | CTC1 [nucleoplasm]

CTC1 [nucleoplasm]

Stable Identifier

R-HSA-9668825

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

CST complex subunit CTC1, CTC1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q2NKJ3 CTC1

Gene Names

CTC1, C17orf68

Chain

chain:1-1217

Reference Genes

BioGPS Gene:80169 CTC1

COSMIC (genes):CTC1 CTC1

CTD Gene:80169 CTC1

dbSNP Gene:80169 CTC1

ENSEMBL:ENSG00000178971 CTC1

HGNC:26169 CTC1

KEGG:hsa:80169 CTC1

Monarch:80169 CTC1

NCBI Gene:80169 CTC1

OMIM:613129 CTC1

UCSC:Q2NKJ3 CTC1

Reference Transcript

RefSeq:NM_025099.5 CTC1

Participates

as an input of

CST complex formation (Homo sapiens)

as a component of

CST complex [nucleoplasm] (Homo sapiens)

Inferred To

ctc1 [nucleoplasm] (Danio rerio)

Ctc1 [nucleoplasm] (Mus musculus)

Ctc1 [nucleoplasm] (Rattus norvegicus)

CTC1 [nucleoplasm] (Bos taurus)

CTC1 [nucleoplasm] (Canis familiaris)

CTC1 [nucleoplasm] (Dictyostelium discoideum)

CTC1 [nucleoplasm] (Gallus gallus)

CTC1 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_079375.3

OpenTargets

ENSG00000178971

ENSEMBL

ENSP00000498499, ENSP00000396018, ENST00000449476, ENSG00000178971, ENST00000651323

HPA

ENSG00000178971-CTC1

GeneCards

CTC1

PRO

Q2NKJ3

Pharos - Targets

Q2NKJ3

PDB

8D0B, 5W2L, 8SOK, 7U5C, 8SOJ, 8D0K, 6W6W

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H668 STN1	1	STN1 [nucleoplasm] (R-HSA-9668821)	0.823	10
UniProt:Q86WV5 TEN1	1	TEN1 [nucleoplasm] (R-HSA-9668823)	0.773	6
UniProt:Q9UF02 CCG5			0.643	3
UniProt:Q92624 APBP2			0.556	3
UniProt:O75496 GMNN	2	GMNN [nucleoplasm] (R-HSA-113554) PolyUb-GMNN [nucleoplasm] (R-HSA-68585)	0.527	2
UniProt:Q5VWX1 KHDRBS2	2	KHDRBS2 [nucleoplasm] (R-HSA-8849028) p-Y-KHDRBS2 [nucleoplasm] (R-HSA-8849031)	0.527	2
UniProt:Q9UL42 PNMA2			0.527	3
UniProt:Q8N9N8 EIF1A			0.527	2
UniProt:Q9BRK4 LZTS2			0.527	2
UniProt:Q13107 USP4	1	USP4 [cytosol] (R-HSA-5212663)	0.527	2
UniProt:Q9Y2B0 CNPY2			0.527	2
UniProt:Q01664 TFAP4			0.527	2
UniProt:Q99435 NELL2	1	NELL2 [extracellular region] (R-HSA-9010198)	0.527	2
UniProt:Q8N5Z5 KCD17			0.527	3
UniProt:Q5TGI0 FAXC			0.527	3
UniProt:Q99615 DNAJC7	2	DNAJC7 [nucleoplasm] (R-HSA-5255408) DNAJC7 [cytosol] (R-HSA-5252099)	0.527	2

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