Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
p-HCK [cytosol]
Stable Identifier
R-HSA-9676060
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Tyrosine-protein kinase HCK ecNumber2.7.10.2/ecNumber, HCK_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by CSF3 (G-CSF) (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds STAT1,3,5 (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:STAT1,3,5 [plasma membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 dissociates yielding CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 and p-Y-STAT1,3,5 (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 [plasma membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 binds and phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2) (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-SHC1:GRB2:p-Y643-GAB2:p-Y546,Y584-PTPN11 [plasma membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
Inactivation of CSF3 (G-CSF) signaling (Homo sapiens)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Homo sapiens)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [lysosomal membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
SOCS1,3 binds p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
SOCS1,3:p-4Y-CSF3R:CSF3dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Homo sapiens)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 [endocytic vesicle membrane] (Homo sapiens)
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds CUL5, ELOB, ELOC, RNF7 (Homo sapiens)
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 [endocytic vesicle membrane] (Homo sapiens)
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 is endocytosed (Homo sapiens)
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
SOCS1,3:p-4Y-CSF3R:CSF3dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
p-Y-JAK1,2 phosphorylates STAT1,3,5 in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-Y-JAK2:p-TYK2 (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:STAT1,3,5 [plasma membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 [plasma membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
SOCS1,3:p-4Y-CSF3R:CSF3dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-SHC1:GRB2:p-Y643-GAB2:p-Y546,Y584-PTPN11 [plasma membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
p-HCK [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08631 HCK
Gene Names
HCK
Chain
initiator methionine:, chain:2-526, initiator methionine:
Reference Genes
BioGPS Gene:3055 HCK
COSMIC (genes):HCK HCK
CTD Gene:3055 HCK
dbSNP Gene:3055 HCK
ENSEMBL:ENSG00000101336 HCK
HGNC:4840 HCK
KEGG:hsa:3055 HCK
Monarch:3055 HCK
NCBI Gene:3055 HCK
OMIM:142370 HCK
UCSC:P08631 HCK
Reference Transcript
RefSeq:NM_002110.3 HCK
RefSeq:NM_001172129.1 HCK
RefSeq:NM_001172133.1 HCK
RefSeq:NM_001172130.1 HCK
RefSeq:NM_001172131.1 HCK
Participates
as a component of
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [lysosomal membrane] (Homo sapiens)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [plasma membrane] (Homo sapiens)
Other forms of this molecule
HCK [cytosol]
Inferred To
phospho-p-HCK [cytosol]
(Bos taurus)
phospho-p-HCK [cytosol]
(Drosophila melanogaster)
phospho-p-HCK [cytosol]
(Gallus gallus)
phospho-p-HCK [cytosol]
(Mus musculus)
phospho-p-HCK [cytosol]
(Rattus norvegicus)
phospho-p-HCK [cytosol]
(Sus scrofa)
phospho-p-HCK [cytosol]
(Xenopus tropicalis)
phospho-HCK [cytosol]
(Canis familiaris)
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
RefSeq
NP_002101.2
,
NP_001165600.1
,
NP_001165604.1
,
NP_001165601.1
,
NP_001165602.1
Guide to Pharmacology - Targets
2032
OpenTargets
ENSG00000101336
ENSEMBL
ENSP00000429848
,
ENSP00000486627
,
ENST00000518730
,
ENSP00000427757
,
ENST00000629881
,
ENSG00000101336
,
ENSP00000365022
,
ENSP00000365012
,
ENST00000520553
,
ENST00000375862
,
ENST00000375852
ZINC - FDA approved
HCK_HUMAN
ZINC - Substances
HCK_HUMAN
ZINC - Biogenic
HCK_HUMAN
ZINC target
P08631
PRO
P08631
GlyGen
P08631
PDB
1AD5
,
2HK5
,
1QCF
,
8F2P
,
9BYJ
,
3HCK
,
3REA
,
3REB
,
3VS7
,
5HCK
,
2HCK
,
3RBB
,
3VS6
,
5H0B
,
5NUH
,
3VS5
,
3VS4
,
5H09
,
3VS3
,
5H0H
,
1BU1
,
3VRZ
,
4HCK
,
5H0G
,
2C0I
,
3VRY
,
3VS2
,
3VS1
,
4LUD
,
5H0E
,
5ZJ6
,
3NHN
,
2C0O
,
3VS0
,
2C0T
,
4U5W
,
2OJ2
,
4LUE
,
2OI3
,
4ORZ
ZINC - Investigational
HCK_HUMAN
IntEnz
2.7.10.2
GeneCards
HCK
HPA
ENSG00000101336-HCK
Pharos - Targets
P08631
ZINC - Predictions - Purchasable
HCK_HUMAN
HMDB Protein
HMDBP01256
Interactors (30)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q07666 KHDRBS1
3
p-Y435,Y440,Y443-KHDRBS1 [nucleoplasm]
(R-HSA-8848970)
p-Y435,Y440,Y443-KHDRBS1 [cytosol]
(R-HSA-8848995)
KHDRBS1 [nucleoplasm]
(R-HSA-8848941)
0.78
4
UniProt:P27958 POLG
1
POLG [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HCV-8854138)
0.729
5
UniProt:P42768 WAS
2
WAS [cytosol]
(R-HSA-201879)
p-Y291-WAS [cytosol]
(R-HSA-2197668)
0.718
9
UniProt:Q13444 ADAM15
1
ADAM15 [plasma membrane]
(R-HSA-708329)
0.713
4
UniProt:Q8WUM4 PDCD6IP
1
PDCD6IP [cytosol]
(R-HSA-917717)
0.709
4
UniProt:Q07889 SOS1
3
SOS1 [cytosol]
(R-HSA-64847)
SOS1 [plasma membrane]
(R-HSA-983559)
p-4S-SOS1 [cytosol]
(R-HSA-109821)
0.692
4
UniProt:P08238 HSP90AB1
6
HSP90AB1 [lysosomal lumen]
(R-HSA-9622846)
HSP90AB1 [nucleoplasm]
(R-HSA-5082399)
HSP90AB1 [cytosol]
(R-HSA-419617)
HSP90AB1 [ficolin-1-rich granule lumen]
(R-HSA-6801491)
HSP90AB1 [extracellular region]
(R-HSA-6806463)
HSP90AB1 [secretory granule lumen]
(R-HSA-6801477)
0.669
4
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.653
3
UniProt:P03407 NEF
0.646
4
UniProt:Q9ULH1 ASAP1
1
ASAP1 [cytosol]
(R-HSA-5620905)
0.609
2
UniProt:O92972 POLG
0.589
2
UniProt:P04324 NEF
0.558
2
UniProt:O43184 ADAM12
1
ADAM12 [plasma membrane]
(R-HSA-179792)
0.558
2
IntAct:EBI-7149158 PD1
0.558
2
UniProt:Q7Z3S9 NOTCH2NLA
3
NOTCH2NLA [extracellular region]
(R-HSA-9908935)
NOTCH2NLA(1-?) [extracellular region]
(R-HSA-9911493)
NOTCH2NLA(?-236) [extracellular region]
(R-HSA-9911490)
0.556
3
UniProt:Q6A162 KRT40
1
KRT40 [cytosol]
(R-HSA-6809605)
0.556
3
UniProt:Q5JR59 MTUS2
0.556
3
UniProt:P60411 KRTAP10-9
1
KRTAP10-9 [cytosol]
(R-HSA-6810277)
0.556
3
UniProt:Q9HD26 GOPC
3
GOPC [Golgi-associated vesicle membrane]
(R-HSA-5627067)
GOPC [plasma membrane]
(R-HSA-5626572)
GOPC [lysosomal membrane]
(R-HSA-5627281)
0.556
3
UniProt:P03406 NEF
0.542
2
UniProt:P07948 LYN
7
LYN [cytosol]
(R-HSA-354251)
MyrG2-PalmC3-LYN [plasma membrane]
(R-HSA-9606875)
p-Y397-LYN [plasma membrane]
(R-HSA-2454229)
p-Y397-LYN [cytosol]
(R-HSA-8942608)
LYN [plasma membrane]
(R-HSA-197943)
MyrG2-PalmC3-LYN [endocytic vesicle membrane]
(R-HSA-9705728)
MyrG2-PalmC3-LYN [lysosomal membrane]
(R-HSA-9707903)
0.527
3
UniProt:P07900 HSP90AA1
8
HSP90AA1 [lysosomal lumen]
(R-HSA-9622850)
HSP90AA1 [cytosol]
(R-HSA-192864)
HSP90AA1 [nucleoplasm]
(R-HSA-5082401)
HSP90AA1 [plasma membrane]
(R-HSA-534996)
HSP90AA1 [ficolin-1-rich granule lumen]
(R-HSA-6801470)
HSP90AA1 [extracellular region]
(R-HSA-3221946)
HSP90AA1 [secretory granule lumen]
(R-HSA-6801515)
HSP90AA1 [endocytic vesicle lumen]
(R-HSA-3221912)
0.527
3
UniProt:Q16543 CDC37
1
CDC37 [cytosol]
(R-HSA-1221609)
0.527
3
UniProt:Q92556 ELMO1
1
ELMO1 [cytosol]
(R-HSA-200932)
0.524
4
UniProt:Q13177 PAK2
11
p-S141,T402-PAK2 [cytosol]
(R-HSA-399824)
PAK2 [cytosol]
(R-HSA-211604)
p-5S-PAK2 [cytosol]
(R-HSA-211609)
PAK2(213-524) [cytosol]
(R-HSA-211653)
p-5S-PAK2(2-212) [cytosol]
(R-HSA-211588)
p-T402-PAK2(213-524) [cytosol]
(R-HSA-211654)
p-T402-PAK2(213-524) [nucleoplasm]
(R-HSA-211709)
K48polyUb-p-T402-PAK-2p43 [cytosol]
(R-HSA-3095873)
p-Y130,S141,T402-PAK2 [cytosol]
(R-HSA-5218705)
PAK2(1-524) [plasma membrane]
(R-HSA-164946)
p-S141,T402-PAK2 [plasma membrane]
(R-HSA-5096524)
0.524
2
UniProt:Q90VU7 Q90VU7
0.524
2
UniProt:Q9QPN3 NEF
0.524
3
IntAct:EBI-7355238 Q85737
0.524
3
UniProt:P12504 VIF
0.524
3
UniProt:P59046 NLRP12
5
NLRP12(241-1061) [cytosol]
(R-HSA-9729690)
NLRP12(1-937) [cytosol]
(R-HSA-9729744)
NLRP12(938-1061) [cytosol]
(R-HSA-9729702)
NLRP12(1-240) [cytosol]
(R-HSA-9729718)
NLRP12 [cytosol]
(R-HSA-561195)
0.508
4
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
