Reactome | PLEKHG4 [cytosol]

PLEKHG4 [cytosol]

Stable Identifier

R-HSA-9679579

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Puratrophin-1 alternativeName: Pleckstrin homology domain-containing family G member 4, PRTPHN1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q58EX7 PLEKHG4

Gene Names

PLEKHG4, PRTPHN1

Chain

chain:1-1191

Reference Genes

BioGPS Gene:25894 PLEKHG4

COSMIC (genes):PLEKHG4 PLEKHG4

CTD Gene:25894 PLEKHG4

dbSNP Gene:25894 PLEKHG4

ENSEMBL:ENSG00000196155 PLEKHG4

ENSEMBL_homo_sapiens_GENE:ENSG00000196155.13 PLEKHG4

HGNC:24501 PLEKHG4

KEGG Gene (Homo sapiens):25894 PLEKHG4

Monarch:25894 PLEKHG4

NCBI Gene:25894 PLEKHG4

OMIM:609526 PLEKHG4

UCSC:Q58EX7 PLEKHG4

Reference Transcript

Other Identifiers

11737692_a_at

16820104

228171_PM_s_at

228171_s_at

25894

3665104

3665411

3665412

3665413

3665414

3665415

3665416

3665417

3665418

3665419

3665420

3665421

3665422

3665424

3665426

3665427

3665429

3665430

3665431

3665433

3665437

3665438

3665439

3665440

3665441

3665442

3665444

3665446

3665447

3665448

3665449

3665450

3665452

3665453

3665454

3665455

45675_at

7996516

A_23_P345460

A_33_P3302957

GE56467

GO:0005085

GO:0005515

GO:0005737

GO:0005829

GO:0005886

GO:0007411

GO:0019898

GO:0023052

GO:0030154

GO:0048856

GO:0051056

GO:0098772

HMNXSV003045882

Hs.49725.0.A1_3p_a_at

ILMN_1736242

PH_hs_0022902

TC16000538.hg

Participates

as a candidate of

as a member of

CDC42 GEFs [cytosol] (Homo sapiens)

Inferred To

Dmel\CG15611 [cytosol] (Drosophila melanogaster)

Homologues of PLEKHG4 [cytosol] (Drosophila melanogaster)

CG15612 [cytosol] (Drosophila melanogaster)

trio [cytosol] (Drosophila melanogaster)

Arhgef25 [cytosol] (Mus musculus)

Arhgef25 [cytosol] (Rattus norvegicus)

ARHGEF25 [cytosol] (Bos taurus)

ARHGEF25 [cytosol] (Canis familiaris)

ARHGEF25 [cytosol] (Sus scrofa)

unc-73 [cytosol] (Caenorhabditis elegans)

arhgef25 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001123201.1, XP_011521289.1, NP_001123199.1, XP_011521288.1, XP_011521290.1, XP_011521287.1, NP_001123200.1, NP_001123203.1

OpenTargets

ENSG00000196155

GeneCards

Q58EX7

HPA

ENSG00000196155-PLEKHG4

Ensembl

ENST00000360461, ENSP00000401118, ENSP00000462601, ENSP00000457086, ENST00000563969, ENSP00000353646, ENST00000393966, ENST00000427155, ENSP00000368649, ENST00000450733, ENST00000379344, ENSG00000196155, ENSP00000398030

PRO

Q58EX7

Pharos - Targets

Q58EX7

Orphanet

15107

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75604 USP2	2	USP2 [cytosol] (R-HSA-5212661) USP2 [nucleoplasm] (R-HSA-5689946)	0.556	3
UniProt:Q99633 PRPF18	1	PRPF18 [nucleoplasm] (R-HSA-5688093)	0.556	3
UniProt:P31273 HOXC8	1	HOXC8 [nucleoplasm] (R-HSA-3222311)	0.556	3
UniProt:Q9NQ94 A1CF	1	A1CF [nucleoplasm] (R-HSA-3211440)	0.556	3
UniProt:Q15475 SIX1	1	SIX1 [nucleoplasm] (R-HSA-9757860)	0.556	3
UniProt:Q6W0C5 DPPA3	2	DPPA3 [cytosol] (R-HSA-9818458) DPPA3 [nucleoplasm] (R-HSA-9817479)	0.556	3
UniProt:Q13330 MTA1	2	MTA1 [nucleoplasm] (R-HSA-3465550) polySUMO2,3-K509-MTA1 [nucleoplasm] (R-HSA-3465537)	0.556	3

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