Reactome | BRD4 [nucleoplasm]

Stable Identifier

R-HSA-9680425

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Bromodomain-containing protein 4, BRD4_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O60885 BRD4

Gene Names

BRD4, HUNK1

Chain

chain:1-1362

Reference Genes

COSMIC (genes):BRD4 BRD4

dbSNP Gene:23476 BRD4

ENSEMBL:ENSG00000141867 BRD4

Participates

as a component of

as an input of

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q04206 RELA	7	RELA [nucleoplasm] (R-HSA-177676) RELA [cytosol] (R-HSA-168172) p-S276-RELA [nucleoplasm] (R-HSA-5624468) p-S276,5xAcK-RELA [nucleoplasm] (R-HSA-5660642) polySUMO3-K37,K122,K123-RELA [nucleoplasm] (R-HSA-4755466) p-S536-RELA [nucleoplasm] (R-HSA-9861499) MeK310-RELA [nucleoplasm] (R-HSA-8865233)	0.811	8
UniProt:Q6NYC1 JMJD6	1	JMJD6 [nucleoplasm] (R-HSA-4754226)	0.782	11
UniProt:P03120 VE2			0.765	5
UniProt:Q86YD7 F90A1			0.761	7
ChEBI:83406 MS-417			0.645	5
UniProt:Q15672 TWIST1	1	TWIST1 [nucleoplasm] (R-HSA-445442)	0.623	7
UniProt:P03122 VE2			0.619	4
UniProt:P06790 VE2			0.573	2
UniProt:P04015 VE2			0.573	3
UniProt:A6NLX3 SPDE4			0.539	4
UniProt:Q8NCB2 CAMKV			0.527	2
UniProt:P48426 PIP4K2A	2	PIP4K2A [cytosol] (R-HSA-1604641) PIP4K2A [nucleoplasm] (R-HSA-6811484)	0.527	2
UniProt:Q96QE3 ATAD5			0.527	2
UniProt:P0DTC4 E	9	Ub-3xPalmC-E [virion membrane] (R-COV-9698416) Ub-3xPalmC-E [endocytic vesicle membrane] (R-COV-9698422) Ub-3xPalmC-E [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698420) Ub-3xPalmC-E [Golgi membrane] (R-COV-9694687) Ub-3xPalmC-E [endoplasmic reticulum membrane] (R-COV-9694465) Ub-3xPalmC-E [endoplasmic reticulum lumen] (R-COV-9694423) 3xPalmC-E [endoplasmic reticulum lumen] (R-COV-9694305) nascent E [endoplasmic reticulum lumen] (R-COV-9694312) N-glycan E [endoplasmic reticulum lumen] (R-COV-9694754)	0.527	2
UniProt:P04798 CYP1A1	1	CYP1A1 [endoplasmic reticulum membrane] (R-HSA-52623)	0.527	2

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