Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand)

Stable Identifier
R-HSA-9685906
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
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General
SVG |   | PPTX  | SBGN
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SARS-CoV-1 plus strand subgenomic mRNAs share a 3'UTR with the plus strand genomic RNA, and as this 3'UTR possesses a polyadenylation signal, they undergo polyadenylation by an undetermined viral RNA polymerase, possibly nsp8 or nsp12 (Spagnolo and Hogue 2000, Peng et al. 2016, Tvarogova et al. 2019).

Literature References
PubMed ID Title Journal Year
27760233 Characterization of the Role of Hexamer AGUAAA and Poly(A) Tail in Coronavirus Polyadenylation

Peng, YH, Lin, CH, Lin, CN, Lo, CY, Tsai, TL, Wu, HY

PLoS ONE 2016
Participants
Participant Of
Disease
Name Identifier Synonyms
severe acute respiratory syndrome 2945 SARS-CoV infection, SARS
Authored
Reviewed
Created
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