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SLK [cytosol]
Stable Identifier
R-HSA-9690228
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
STE20-like serine/threonine-protein kinase, SLK_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA binds effectors at the plasma membrane (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
SLK [cytosol] (Homo sapiens)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
SLK [cytosol] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB binds effectors at the plasma membrane (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
SLK [cytosol] (Homo sapiens)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
SLK [cytosol] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC binds effectors at the plasma membrane (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
SLK [cytosol] (Homo sapiens)
RHOC:GTP:RHOC effectors [plasma membrane] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
SLK [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H2G2 SLK
Gene Names
SLK, KIAA0204, STK2
Chain
chain:1-1235
Reference Genes
BioGPS Gene:9748 SLK
COSMIC (genes):SLK SLK
CTD Gene:9748 SLK
dbSNP Gene:9748 SLK
ENSEMBL:ENSG00000065613 SLK
HGNC:11088 SLK
Monarch:9748 SLK
NCBI Gene:9748 SLK
OMIM:616563 SLK
UCSC:Q9H2G2 SLK
Reference Transcript
RefSeq:NM_014720.3 SLK
RefSeq:NM_001304743.1 SLK
Other Identifiers
11725219_a_at
11725220_a_at
11746090_a_at
16708887
206874_PM_s_at
206874_s_at
206875_PM_s_at
206875_s_at
3262432
3262434
3262435
3262436
3262437
3262438
3262440
3262442
3262443
3262444
3262445
3262446
3262447
3262448
3262449
3262450
3262451
3262454
3262456
3262457
3262459
3262460
3262461
3262464
3262468
3262469
3262470
3262471
3262472
3262473
3262474
3262476
3262477
3262478
3262479
3262480
38669_at
7930276
91586_at
9748
A_14_P110800
A_14_P135622
A_23_P202199
A_24_P146670
D86959_at
GE81954
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005737
GO:0005829
GO:0006468
GO:0006915
GO:0007010
GO:0012501
GO:0016740
GO:0030334
GO:0031122
GO:0031252
GO:0042802
GO:0042803
GO:0042981
GO:0043226
GO:0045296
GO:0046777
GO:0048471
GO:0051893
GO:0070062
GO:0106310
GO:0140096
HMNXSV003040539
Hs.105751.0.S2_3p_a_at
ILMN_1700834
ILMN_2159322
PH_hs_0005882
TC10000779.hg
g7661993_3p_s_at
Participates
as a member of
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
as a candidate of
RHOC effectors [cytosol] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
Inferred To
gck-4 [cytosol]
(Caenorhabditis elegans)
SLK [cytosol]
(Bos taurus)
SLK [cytosol]
(Canis familiaris)
SLK [cytosol]
(Drosophila melanogaster)
SLK [cytosol]
(Gallus gallus)
SLK [cytosol]
(Mus musculus)
SLK [cytosol]
(Rattus norvegicus)
SLK [cytosol]
(Schizosaccharomyces pombe)
SLK [cytosol]
(Sus scrofa)
Cross References
ZINC - World Drugs
SLK_HUMAN
Guide to Pharmacology - Targets
2200
ENSEMBL
ENSP00000336824
,
ENSP00000358770
,
ENST00000369755
,
ENST00000335753
OpenTargets
ENSG00000065613
ZINC - FDA approved
SLK_HUMAN
ZINC - Substances
SLK_HUMAN
ZINC - Biogenic
SLK_HUMAN
ZINC target
Q9H2G2
PRO
Q9H2G2
GlyGen
Q9H2G2
PDB
2JFL
,
8BEM
,
6HVD
,
2J51
,
2UV2
,
2JFM
,
4USF
ZINC - Investigational
SLK_HUMAN
HPA
ENSG00000065613-SLK
Pharos - Targets
Q9H2G2
ZINC - Predictions - Purchasable
SLK_HUMAN
HMDB Protein
HMDBP09504
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