Reactome | RAP1GDS1 [mitochondrial outer membrane]

RAP1GDS1 [mitochondrial outer membrane]

Stable Identifier

R-HSA-9693756

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

Vimar

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P52306 RAP1GDS1

Gene Names

RAP1GDS1, SMGGDS

Chain

chain:1-607

Reference Genes

BioGPS Gene:5910 RAP1GDS1

COSMIC (genes):RAP1GDS1 RAP1GDS1

CTD Gene:5910 RAP1GDS1

dbSNP Gene:5910 RAP1GDS1

ENSEMBL:ENSG00000138698 RAP1GDS1

ENSEMBL_homo_sapiens_GENE:ENSG00000138698.15 RAP1GDS1

HGNC:9859 RAP1GDS1

KEGG Gene (Homo sapiens):5910 RAP1GDS1

Monarch:5910 RAP1GDS1

NCBI Gene:5910 RAP1GDS1

OMIM:179502 RAP1GDS1

UCSC:P52306 RAP1GDS1

Reference Transcript

Other Identifiers

11719378_a_at

11719379_a_at

11735692_a_at

1624_at

16969093

209444_PM_at

209444_at

217457_PM_s_at

217457_s_at

2736842

2736854

2736855

2736856

2736859

2736863

2736870

2736879

2736883

2736887

2736888

2736889

2736890

2736891

2736894

2736895

2736901

2736902

2736903

2736904

2736905

2736906

32602_at

3286654

5910

8096538

A_14_P120225

A_23_P58207

A_32_P85813

A_33_P3215123

GE55003

GO:0003012

GO:0003013

GO:0003300

GO:0005085

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005739

GO:0005783

GO:0005829

GO:0007005

GO:0007010

GO:0010821

GO:0014829

GO:0023052

GO:0030695

GO:0031034

GO:0032471

GO:0034504

GO:0043226

GO:0043547

GO:0051561

GO:0051604

GO:0055065

GO:0065003

GO:0070062

GO:0070376

GO:0080120

GO:0086098

GO:0098772

GO:1904464

HMNXSV003002331

Hs.7940.1.S1_3p_a_at

ILMN_1687724

ILMN_1806266

ILMN_2106167

PH_hs_0022496

TC04000510.hg

g12804812_3p_at

Cross References

RefSeq

NP_066982.3, NP_001093897.1, NP_001093899.1, NP_001093898.1, NP_001093896.1, NP_001093900.1

OpenTargets

ENSG00000138698

GeneCards

P52306

HPA

ENSG00000138698-RAP1GDS1

Ensembl

ENST00000339360, ENSG00000138698, ENSP00000407157, ENST00000408927, ENSP00000264572, ENST00000264572, ENSP00000386153, ENST00000453712, ENSP00000386223, ENSP00000369503, ENSP00000340454, ENST00000380158, ENST00000408900

PRO

P52306

Pharos - Targets

P52306

PDB

5ZHX, 5XGC

HMDB Protein

HMDBP01779

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTD1-PRO_0000449620 REP			0.836	6
UniProt:P61586 RHOA	6	RHOA [ficolin-1-rich granule membrane] (R-HSA-6804971) RHOA [secretory granule membrane] (R-HSA-6804980) RHOA [endoplasmic reticulum membrane] (R-HSA-5672082) RHOA [cytosol] (R-HSA-194866) RHOA [cell junction] (R-HSA-2134503) RHOA [plasma membrane] (R-HSA-194510)	0.788	7
UniProt:P63000 RAC1	6	RAC1 [ficolin-1-rich granule membrane] (R-HSA-6804802) RAC1 [secretory granule membrane] (R-HSA-6804770) GGC-PalmC-RAC1 [plasma membrane] (R-HSA-2316446) RAC1 [endoplasmic reticulum membrane] (R-HSA-5672076) RAC1 [cytosol] (R-HSA-442615) RAC1 [plasma membrane] (R-HSA-351141)	0.738	4
UniProt:Q9UF11 PKHB1			0.666	5
UniProt:P08134 RHOC	3	RHOC [plasma membrane] (R-HSA-194870) RHOC [cytosol] (R-HSA-194853) RHOC [endoplasmic reticulum membrane] (R-HSA-9714362)	0.643	4
UniProt:Q9NS73-5 MBIP			0.556	3
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2
UniProt:P60953 CDC42	3	CDC42 [endoplasmic reticulum membrane] (R-HSA-5672086) CDC42 [cytosol] (R-HSA-442630) CDC42 [plasma membrane] (R-HSA-449545)	0.547	2
UniProt:Q4LDG9 DNAL1			0.527	3
UniProt:Q8TCD5 NT5C	1	NT5C [cytosol] (R-HSA-109467)	0.527	2
UniProt:P60763 RAC3	3	RAC3 [endoplasmic reticulum membrane] (R-HSA-9714693) RAC3 [plasma membrane] (R-HSA-195338) RAC3 [cytosol] (R-HSA-195335)	0.527	2
UniProt:O95057 DIRA1			0.527	3
UniProt:Q96HU8 DIRA2			0.527	3
UniProt:Q9BQS6 HSPB9			0.527	2
UniProt:Q9Y3Q8 T22D4			0.527	4
UniProt:Q9Y3L5 RAP2C	2	RAP2C [plasma membrane] (R-HSA-6804983) RAP2C [tertiary granule membrane] (R-HSA-6804975)	0.527	3
UniProt:P59190 RAB15	2	GGC-RAB15 [cytosol] (R-HSA-8873782) RAB15 [cytosol] (R-HSA-8873682)	0.527	3
UniProt:P15153 RAC2	5	RAC2 [endoplasmic reticulum membrane] (R-HSA-9714482) RAC2 [mitochondrial outer membrane] (R-HSA-9714496) RAC2 [phagocytic vesicle membrane] (R-HSA-5668620) RAC2 [cytosol] (R-HSA-195343) RAC2 [plasma membrane] (R-HSA-195339)	0.527	2
UniProt:Q5HYI8 RABL3			0.527	3
UniProt:P62834 RAP1A	4	RAP1A [plasma membrane] (R-HSA-354118) RAP1A [endosome membrane] (R-HSA-190053) RAP1A [cytosol] (R-HSA-169884) RAP1A [specific granule membrane] (R-HSA-6806137)	0.527	3
UniProt:Q6NXR0 IIGP5			0.527	2
UniProt:P56559 ARL4C	1	ARL4C [plasma membrane] (R-HSA-9618406)	0.527	3
UniProt:P61224 RAP1B	2	RAP1B [azurophil granule membrane] (R-HSA-6804972) RAP1B [plasma membrane] (R-HSA-377590)	0.527	2

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