BARD1 C50G [nucleoplasm]

Stable Identifier
R-HSA-9699137
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
BARD1 Cys50Gly
Icon
BARD1 C50G [nucleoplasm] icon
BARD1 C50G [nucleoplasm] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
12431996 Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein

Pao, GM, Xia, Y, Verma, IM, Chen, HW, Hunter, T

J. Biol. Chem. 2003
External Reference Information
External Reference
UniProt:Q99728 BARD1
Gene Names
BARD1
Chain
chain:1-777
Reference Genes
COSMIC (genes):BARD1 BARD1
dbSNP Gene:580 BARD1
ENSEMBL:ENSG00000138376 BARD1
Participates
as a candidate of
Other forms of this molecule
K6PolyUb,p-T714,T734-BARD1 [nucleoplasm]
p-T714,T734-BARD1 [nucleoplasm]
BARD1 [nucleoplasm]
K6PolyUb-BARD1 [nucleoplasm]
BARD1 C83G [nucleoplasm]
BARD1 L44R [nucleoplasm]
BARD1 H68Y [nucleoplasm]
BARD1 W34R [nucleoplasm]
BARD1 G623W [nucleoplasm]
BARD1 C53W [nucleoplasm]
BARD1 C71Y [nucleoplasm]
BARD1 G623E [nucleoplasm]
Modified Residues
Name
L-cysteine 50 replaced with glycine
Coordinate
50
PsiMod
L-cysteine removal [MOD:01635]
A protein modification that effectively removes or replaces an L-cysteine.
glycine residue [MOD:00017]
A protein modification that effectively converts a source amino acid residue to a glycine.
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
ClinGen
Interactors (27)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P38398 BRCA1  20 0.958 20
 UniProt:O95751 LDOC1      0.781 7
 UniProt:Q08379 GOLGA2  3 0.718 6
 UniProt:P33240 CSTF2  1 0.702 8
 ChEBI:61151 PAR      0.65 9
 UniProt:Q05048 CSTF1  1 0.581 4
 UniProt:O95453 PARN  1 0.577 4
 ChEBI:16864 ADP-RIBOSE      0.558 2
 UniProt:O75031 HSF2B      0.556 3
 UniProt:Q8NHQ1 CEP70  1 0.556 3
 UniProt:Q5JR59-3 MTUS2      0.556 3
 UniProt:O00471 EXOC5  2 0.556 3
 UniProt:Q9Y2T1 AXIN2  4 0.556 3
 UniProt:Q13077 TRAF1  3 0.556 3
 UniProt:Q8N720 ZNF655  1 0.556 3
 UniProt:Q13422-7 IKZF1      0.556 3
 UniProt:Q9BVG8-5 KIFC3      0.556 3
 UniProt:Q6A162 KRT40  1 0.556 3
 UniProt:Q8IZU0 FAM9B      0.556 3
 IntAct:EBI-16435328 CCSB ORF ID      0.556 3
 UniProt:Q15276 RABEP1  1 0.556 3
 UniProt:P38398-1 BRCA1      0.524 3
 UniProt:Q9P2H0 CE126      0.508 2
 UniProt:O95251 KAT7  1 0.508 2
 UniProt:Q12873 CHD3  2 0.508 2
 UniProt:O14776 TCERG1  1 0.508 2
 UniProt:Q9Y2X7 GIT1  2 0.508 2
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