TFG(1-240)-p-7Y-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9702038
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Protein TFG, TFG_HUMAN, TFGxl
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
11943732 Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALK(XL) chimeric gene with transforming activity

Bellosillo, B, Morris, SW, Pulford, K, Rosenwald, A, Beà, S, Mason, D, Hernández, L, Pinyol, M, Ott, G, Falini, B, Santos, E, Fernández, A, Carbone, A, Campo, E

Am. J. Pathol. 2002
External Reference Information
External Reference
Gene Names
TFG
Chain
chain:1-400
Other Identifiers
10342
11715598_at
16943375
217839_PM_at
217839_at
239385_PM_at
239385_at
244614_PM_at
244614_at
2633774
2633775
2633776
2633777
2633779
2633780
2633781
2633782
2633784
2633787
2633788
2633789
2633790
2633791
2633796
2633797
2633798
2633799
2633800
2633801
2633802
2633805
2633806
2633807
2633809
70744_at
77377_at
8081316
88110_at
A_14_P136435
A_23_P29517
A_24_P345822
GE61614
GE738883
GE85285
GO:0005515
GO:0005737
GO:0005783
GO:0005829
GO:0006888
GO:0016192
GO:0042802
GO:0043123
GO:0043226
GO:0043231
GO:0048208
GO:0065003
GO:0070971
HMNXSV003004113
HMNXSV003056027
Hs.142230.0.A1_3p_at
Hs.209245.0.A1_3p_at
ILMN_1779213
ILMN_1812474
ILMN_2341815
PH_hs_0026111
TC03000512.hg
g5174718_3p_at
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 1058 to 1620 at 241 from UniProt:Q9UM73 ALK
Coordinate
241
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1358
Coordinate
1358
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
anaplastic large cell lymphoma DOID:0050744
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Interactors (11)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9Y5V3 MAGED1  1 0.718 8
 UniProt:P13569 CFTR  17 0.707 7
 UniProt:P52597 HNRNPF  2 0.556 3
 UniProt:O14964 HGS  2 0.556 3
 UniProt:P42858 HTT  1 0.556 3
 UniProt:Q8TDS5 OXER1  1 0.556 3
 UniProt:Q71SY5 MED25  1 0.556 3
 UniProt:O75593 FOXH1  1 0.556 3
 UniProt:P62993 GRB2  1 0.547 2
 UniProt:P55735 SEC13  4 0.527 2
 UniProt:O94979 SEC31A  5 0.527 2
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