ETV6(1-384)-p-6Y-FLT3(573-993) fusion [cytosol]

Stable Identifier
R-HSA-9703308
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Transcription factor ETV6, ETV6_HUMAN, EF1
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
30559310 Two myeloid leukemia cases with rare FLT3 fusions

Olson, S, Zhang, H, Moore, S, Long, N, Paliga, A, Hobbs, E, Tyner, JW, Dao, KT

2018
External Reference Information
External Reference
Gene Names
ETV6, TEL, TEL1
Chain
chain:1-452
Reference Transcript
Other Identifiers
11743165_at
11743166_at
11743167_at
1638_at
16748407
205585_PM_at
205585_at
2120
225764_PM_at
225764_at
235056_PM_at
235056_at
3405041
3405042
3405082
3405100
3405101
3405102
3405103
3405120
3405121
3405122
3405132
3405134
3405135
3405136
3405142
3405152
3405156
3405157
3405162
3405163
3405164
3405175
3405177
38491_at
55594_at
58239_at
70395_at
7953981
92032_at
A_14_P113857
A_23_P105264
A_24_P372862
A_33_P3210343
A_33_P3356325
GE79814
GO:0000122
GO:0000785
GO:0000977
GO:0000978
GO:0000981
GO:0001227
GO:0001228
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005730
GO:0005829
GO:0005886
GO:0006355
GO:0006357
GO:0007296
GO:0012501
GO:0016020
GO:0019904
GO:0022008
GO:0030154
GO:0043226
GO:0043565
GO:0045944
GO:0071425
GO:0097152
GO:0140110
GO:1990837
HMNXSV003053967
Hs.146381.2.S1_3p_at
Hs.293972.0.S1_3p_at
ILMN_1789596
PH_hs_0034188
TC12003210.hg
U11732_at
U63312_at
g4503610_3p_at
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 573 to 993 at 385 from UniProt:P36888 FLT3
Coordinate
385
Name
O4'-phospho-L-tyrosine at 589
Coordinate
589
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 591
Coordinate
591
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 599
Coordinate
599
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 768
Coordinate
768
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 955
Coordinate
955
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 969
Coordinate
969
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
myeloid leukemia DOID:8692 Non-Lymphocytic Leukemia, myeloid granulocytic leukaemia, myeloid leukaemia, leukaemia myelogenous, leukemia myelogenous, myeloid granulocytic leukemia
Cross References
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
PRO
GlyGen
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
Interactors (5)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q13114 TRAF3  4 0.671 5
 UniProt:Q13526 PIN1  2 0.666 4
 UniProt:O75581 LRP6  8 0.643 3
 UniProt:Q16236 NFE2L2  13 0.625 5
 UniProt:O75197 LRP5  5 0.527 3
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