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TMEM186:MT-ND3 [mitochondrial inner membrane]
Stable Identifier
R-HSA-9708002
Type
Complex
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Complex I biogenesis (Homo sapiens)
COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex (Homo sapiens)
370 kDa subcomplex [mitochondrial inner membrane] (Homo sapiens)
TMEM186:MT-ND3 [mitochondrial inner membrane] (Homo sapiens)
TMEM186:MT-ND3 [mitochondrial inner membrane] (Homo sapiens)
ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Homo sapiens)
550kDa complex [mitochondrial inner membrane] (Homo sapiens)
370 kDa subcomplex [mitochondrial inner membrane] (Homo sapiens)
TMEM186:MT-ND3 [mitochondrial inner membrane] (Homo sapiens)
815kDa complex [mitochondrial inner membrane] (Homo sapiens)
550kDa complex [mitochondrial inner membrane] (Homo sapiens)
370 kDa subcomplex [mitochondrial inner membrane] (Homo sapiens)
TMEM186:MT-ND3 [mitochondrial inner membrane] (Homo sapiens)
Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Homo sapiens)
815kDa complex [mitochondrial inner membrane] (Homo sapiens)
550kDa complex [mitochondrial inner membrane] (Homo sapiens)
370 kDa subcomplex [mitochondrial inner membrane] (Homo sapiens)
TMEM186:MT-ND3 [mitochondrial inner membrane] (Homo sapiens)
980kDa complex [mitochondrial inner membrane] (Homo sapiens)
815kDa complex [mitochondrial inner membrane] (Homo sapiens)
550kDa complex [mitochondrial inner membrane] (Homo sapiens)
370 kDa subcomplex [mitochondrial inner membrane] (Homo sapiens)
TMEM186:MT-ND3 [mitochondrial inner membrane] (Homo sapiens)
The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Homo sapiens)
370 kDa subcomplex [mitochondrial inner membrane] (Homo sapiens)
TMEM186:MT-ND3 [mitochondrial inner membrane] (Homo sapiens)
550kDa complex [mitochondrial inner membrane] (Homo sapiens)
370 kDa subcomplex [mitochondrial inner membrane] (Homo sapiens)
TMEM186:MT-ND3 [mitochondrial inner membrane] (Homo sapiens)
The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Homo sapiens)
980kDa complex [mitochondrial inner membrane] (Homo sapiens)
815kDa complex [mitochondrial inner membrane] (Homo sapiens)
550kDa complex [mitochondrial inner membrane] (Homo sapiens)
370 kDa subcomplex [mitochondrial inner membrane] (Homo sapiens)
TMEM186:MT-ND3 [mitochondrial inner membrane] (Homo sapiens)
Complex I [mitochondrial inner membrane] (Homo sapiens)
815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Homo sapiens)
550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Homo sapiens)
370 kDa subcomplex (-MCIA complex) [mitochondrial inner membrane] (Homo sapiens)
TMEM186:MT-ND3 [mitochondrial inner membrane] (Homo sapiens)
Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Homo sapiens)
Complex I [mitochondrial inner membrane] (Homo sapiens)
815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Homo sapiens)
550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Homo sapiens)
370 kDa subcomplex (-MCIA complex) [mitochondrial inner membrane] (Homo sapiens)
TMEM186:MT-ND3 [mitochondrial inner membrane] (Homo sapiens)
Participants
components
MT-ND3 [mitochondrial inner membrane]
(Homo sapiens)
TMEM186 [mitochondrial inner membrane]
(Homo sapiens)
Participates
as an input of
COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex (Homo sapiens)
as a component of
370 kDa subcomplex [mitochondrial inner membrane] (Homo sapiens)
370 kDa subcomplex (-MCIA complex) [mitochondrial inner membrane] (Homo sapiens)
Inferred To
TMEM186:MT-ND3 [mitochondrial inner membrane]
(Bos taurus)
TMEM186:MT-ND3 [mitochondrial inner membrane]
(Caenorhabditis elegans)
TMEM186:MT-ND3 [mitochondrial inner membrane]
(Canis familiaris)
TMEM186:MT-ND3 [mitochondrial inner membrane]
(Danio rerio)
TMEM186:MT-ND3 [mitochondrial inner membrane]
(Drosophila melanogaster)
TMEM186:MT-ND3 [mitochondrial inner membrane]
(Gallus gallus)
TMEM186:MT-ND3 [mitochondrial inner membrane]
(Mus musculus)
TMEM186:MT-ND3 [mitochondrial inner membrane]
(Rattus norvegicus)
TMEM186:MT-ND3 [mitochondrial inner membrane]
(Sus scrofa)
TMEM186:MT-ND3 [mitochondrial inner membrane]
(Xenopus tropicalis)
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