KIF5B(2-575)-ALK(1063-1620) fusion [cytosol]

Stable Identifier
R-HSA-9711964
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Kinesin-1 heavy chain, KINH_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
21656749 A novel KIF5B-ALK variant in nonsmall cell lung cancer

Leung, EL, Tin, VP, Wong, MP, Au, JS, Cheng, LC, Sihoe, AD, Wong, DW, Chung, LP, Wong, SK

Cancer 2011
External Reference Information
External Reference
UniProt:P33176 KIF5B
Gene Names
KIF5B, KNS, KNS1
Chain
initiator methionine:, chain:2-963
Reference Genes
BioGPS Gene:3799 KIF5B
COSMIC (genes):KIF5B KIF5B
CTD Gene:3799 KIF5B
dbSNP Gene:3799 KIF5B
ENSEMBL:ENSG00000170759 KIF5B
ENSEMBL_homo_sapiens_GENE:ENSG00000170759.11 KIF5B
HGNC:6324 KIF5B
KEGG Gene (Homo sapiens):3799 KIF5B
Monarch:3799 KIF5B
NCBI Gene:3799 KIF5B
OMIM:602809 KIF5B
Reference Transcript
Other Identifiers
11736059_a_at
11736060_a_at
11746185_a_at
11757809_s_at
16713085
201991_PM_s_at
201991_s_at
201992_PM_s_at
201992_s_at
224662_PM_at
224662_at
3283990
3283992
3283993
3283994
3283995
3283997
3283998
3283999
3284000
3284001
3284002
3284004
3284005
3284006
3284010
3284012
3284014
3284017
3284018
3284019
3284020
3284022
3284023
3284024
3284025
3284026
3284027
3284028
3284029
3284033
3284035
3284036
3284037
34732_at
3799
57037_at
7932911
A_23_P86403
A_33_P3292332
A_33_P3292337
GE59917
GO:0000166
GO:0002376
GO:0003774
GO:0003777
GO:0003824
GO:0005515
GO:0005524
GO:0005737
GO:0005739
GO:0005764
GO:0005765
GO:0005773
GO:0005815
GO:0005829
GO:0005856
GO:0005871
GO:0005874
GO:0005929
GO:0006886
GO:0007005
GO:0007018
GO:0007028
GO:0007411
GO:0008017
GO:0008092
GO:0008574
GO:0016020
GO:0016787
GO:0016887
GO:0023052
GO:0030139
GO:0030154
GO:0031410
GO:0031982
GO:0032230
GO:0032418
GO:0032839
GO:0034451
GO:0035253
GO:0035617
GO:0042267
GO:0042391
GO:0042802
GO:0043005
GO:0043226
GO:0043227
GO:0043268
GO:0044877
GO:0045296
GO:0045335
GO:0047496
GO:0047497
GO:0048471
GO:0048489
GO:0048856
GO:0051642
GO:0071346
GO:0072383
GO:0072659
GO:0098542
GO:0098971
GO:0099641
GO:0101004
GO:0140657
GO:0160040
GO:1903078
GO:1904115
GO:1990048
GO:1990049
HMNXSV003023944
Hs.149436.0.A1_3p_a_at
Hs.149436.1.A1_3p_at
ILMN_1788160
PH_hs_0008995
TC10001160.hg
X65873_at
g4758647_3p_a_at
Participates
as a member of
as a component of
Other forms of this molecule
KIF5B [cytosol]
KIF5B(2-575)-p-7Y-ALK(1063-1620) fusion [cytosol]
Modified Residues
Name
Insertion of residues 1063 to 1620 at 576 from UniProt:Q9UM73 ALK
Coordinate
576
Disease
Name Identifier Synonyms
non-small cell lung carcinoma DOID:3908 Non-small cell lung cancer (disorder), NSCLC, NSCLC
Cross References
RefSeq
COSMIC
OpenTargets
HPA
GeneCards
ZINC target
Ensembl
PRO
Pharos - Targets
PDB
Interactors (9)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P63104 YWHAZ  2 0.895 7
 UniProt:P31946 YWHAB  1 0.806 5
 UniProt:O95429 BAG4  3 0.556 3
 UniProt:Q14192 FHL2  1 0.556 3
 UniProt:P31947 SFN  1 0.536 2
 UniProt:Q96ES7 SGF29  1 0.527 2
 UniProt:O14977 AZIN1  1 0.527 2
 UniProt:P62258 YWHAE  1 0.483 2
 UniProt:P13569 CFTR  17 0.483 9
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