KLC1(1-420)-p-7Y-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9711978
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Kinesin light chain 1, KLC1_HUMAN
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
22347464 KLC1-ALK: a novel fusion in lung cancer identified using a formalin-fixed paraffin-embedded tissue only

Sugawara, E, Sakata, S, Soda, M, Togashi, Y, Hatano, S, Takeuchi, K, Mano, H, Asaka, R, Nakajima, T

PLoS One 2012
External Reference Information
External Reference
UniProt:Q07866 KLC1
Gene Names
KLC1, KLC, KNS2
Chain
chain:1-573
Reference Genes
COSMIC (genes):KLC1 KLC1
dbSNP Gene:3831 KLC1
ENSEMBL:ENSG00000126214 KLC1
Participates
as a component of
Other forms of this molecule
KLC1(1-420)-ALK(1058-1620) fusion [cytosol]
KLC1 [cytosol]
Modified Residues
Name
Insertion of residues 1058 to 1620 at 421 from UniProt:Q9UM73 ALK
Coordinate
421
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1358
Coordinate
1358
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
lung adenocarcinoma DOID:3910 nonsmall cell adenocarcinoma
Cross References
COSMIC
Interactors (6)
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