Reactome | AAAS [cytosol]

AAAS [cytosol]

Stable Identifier

R-HSA-9714323

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Aladin

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RHOA GTPase cycle (Homo sapiens)
        
        RHOA binds effectors at the plasma membrane (Homo sapiens)
        
        RHOA plasma membrane effectors [cytosol] (Homo sapiens)
        
        AAAS [cytosol] (Homo sapiens)
        
        RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Homo sapiens)
        
        RHOA plasma membrane effectors [cytosol] (Homo sapiens)
        
        AAAS [cytosol] (Homo sapiens)

Literature References

PubMed ID	Title	Journal	Year
19703420	The transmembrane nucleoporin NDC1 is required for targeting of ALADIN to nuclear pore complexes Nishihara, A, Natsume, T, Akiyama, T, Kamiya, A, Iemura, S, Yamazumi, Y, Nishida, A	Biochem Biophys Res Commun	2009

External Reference Information

External Reference

UniProt:Q9NRG9 AAAS

Gene Names

AAAS, ADRACALA, GL003

Chain

initiator methionine:, chain:2-546

Reference Genes

BioGPS Gene:8086 AAAS

COSMIC (genes):AAAS AAAS

CTD Gene:8086 AAAS

dbSNP Gene:8086 AAAS

ENSEMBL:ENSG00000094914 AAAS

ENSEMBL_homo_sapiens_GENE:ENSG00000094914.14 AAAS

ENSEMBL_homo_sapiens_GENE:ENSG00000291836.1 AAAS

HGNC:13666 AAAS

KEGG Gene (Homo sapiens):8086 AAAS

Monarch:8086 AAAS

NCBI Gene:8086 AAAS

OMIM:605378 AAAS

UCSC:Q9NRG9 AAAS

Reference Transcript

Other Identifiers

11716958_a_at

16765284

218075_PM_at

218075_at

3456131

3456133

3456135

3456136

3456137

3456138

3456139

3456140

3456141

3456142

3456144

3456146

3456148

3456150

3456151

3456153

3456154

3456155

65445_at

7963646

8086

GE55635

GO:0000278

GO:0000922

GO:0001578

GO:0003674

GO:0005515

GO:0005634

GO:0005635

GO:0005643

GO:0005654

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0006913

GO:0007010

GO:0007059

GO:0007612

GO:0009566

GO:0015031

GO:0016020

GO:0022414

GO:0031965

GO:0043226

GO:0046822

GO:0050877

GO:0051028

GO:0072686

GO:0090307

GO:0140014

HMNXSV003039478

ILMN_1755321

PH_hs_0024097

TC12001547.hg

g12962936_3p_at

g12962936_3p_x_at

Participates

as a candidate of

RHOA plasma membrane effectors [cytosol] (Homo sapiens)

Other forms of this molecule

AAAS [nuclear envelope]

Inferred To

Aladin [cytosol] (Drosophila melanogaster)

Aaas [cytosol] (Mus musculus)

Aaas [cytosol] (Rattus norvegicus)

AAAS [cytosol] (Bos taurus)

AAAS [cytosol] (Canis familiaris)

AAAS [cytosol] (Gallus gallus)

AAAS [cytosol] (Sus scrofa)

aaas [cytosol] (Danio rerio)

aaas [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_056480.1, NP_001166937.1

OpenTargets

ENSG00000094914

HPA

ENSG00000094914-AAAS

GeneCards

Q9NRG9

Ensembl

ENST00000209873, ENSP00000209873, ENST00000394384, ENSG00000094914, ENSP00000377908

PRO

Q9NRG9

Pharos - Targets

Q9NRG9

Orphanet

15046

PDB

7R5K, 7R5J

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