Reactome | RAC2 binds effectors at the mitochondrial outer membrane

RAC2 binds effectors at the mitochondrial outer membrane

Stable Identifier

R-HSA-9714477

Type

Reaction [uncertain]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

ReviewStatus

5/5

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RAC2 binds effectors at the mitochondrial outer membrane

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RAC2 interacts with several effectors localized at the mitochondrial outer membrane. Since RAC2 localization at the mitochondrial outer membrane and its association with mitochondrial proteins has not been fully established, these effectors are annotated as candidates:
ARMCX3 (Bagci et al. 2020)
MTX1 (Capala et al. 2015)
SAMM50 (Capala et al. 2015)

Literature References

PubMed ID	Title	Journal	Year
26016997	Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2 Schuringa, JJ, Vellenga, E, Kuipers, J, Bonardi, F, Giepmans, BN, van den Boom, V, Capala, ME, Maat, H	PLoS One	2015
31871319	Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms Tran, V, Gingras, AC, Elkholi, IE, Robert, A, Boulais, J, Faubert, D, Dubé, N, Hipfner, DR, Cote, JF, Lin, ZY, Bagci, H, Sriskandarajah, N, Thibault, MP	Nat. Cell Biol.	2020