Reactome | DBN1 [cytosol]

DBN1 [cytosol]

Stable Identifier

R-HSA-9714666

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Drebrin, DREB_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q16643 DBN1

Gene Names

DBN1, D0S117E

Chain

initiator methionine:, chain:2-649

Reference Genes

BioGPS Gene:1627 DBN1

COSMIC (genes):DBN1 DBN1

CTD Gene:1627 DBN1

dbSNP Gene:1627 DBN1

ENSEMBL:ENSG00000113758 DBN1

HGNC:2695 DBN1

KEGG:hsa:1627 DBN1

Monarch:1627 DBN1

NCBI Gene:1627 DBN1

OMIM:126660 DBN1

UCSC:Q16643 DBN1

Reference Transcript

Other Identifiers

11729702_a_at

11729703_a_at

11732120_a_at

1627

17003261

202806_PM_at

202806_at

217025_PM_s_at

217025_s_at

2888799

2888801

2888802

2888803

2888804

2888805

2888807

2888808

2888809

2888810

2888811

2888812

2888813

2888815

2888816

2888817

2888818

2888819

2888820

2888821

2888822

2888823

2888824

2888825

2888828

2888829

2888830

2888831

2888832

2888833

2888834

37981_at

63670_s_at

8116051

A_23_P156284

A_24_P97849

GE79428

GO:0001701

GO:0003779

GO:0005515

GO:0005522

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005911

GO:0005921

GO:0005938

GO:0007015

GO:0007399

GO:0008092

GO:0010643

GO:0010644

GO:0014069

GO:0015629

GO:0016020

GO:0030154

GO:0030425

GO:0030426

GO:0030863

GO:0031915

GO:0032507

GO:0042641

GO:0042995

GO:0043226

GO:0045211

GO:0045296

GO:0048168

GO:0048699

GO:0048856

GO:0050773

GO:0051220

GO:0061003

GO:0061351

GO:0070161

GO:0098978

GO:0099524

GO:1902685

HMNXSV003053472

Hs.89434.1.S1_3p_a_at

ILMN_1757270

ILMN_1769926

PH_hs_0004982

TC05002108.hg

U00802_s_at

g4758123_3p_at

Participates

as a candidate of

Cross References

ENSEMBL

ENST00000292385, ENSP00000292385, ENST00000309007, ENSP00000308532, ENSP00000377195, ENSG00000113758, ENST00000393565

OpenTargets

ENSG00000113758

GeneCards

DBN1

HPA

ENSG00000113758-DBN1

PRO

Q16643

Pharos - Targets

Q16643

GlyGen

Q16643

PDB

5Y1Z, 5ZZ9

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61073 CXCR4	1	CXCR4 [plasma membrane] (R-HSA-2980772)	0.702	5
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.674	4
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	20
UniProt:O35889 Afdn	2	Afadin [cytosol] (R-RNO-433723) Afdn [cytosol] (R-RNO-418342)	0.576	3
UniProt:Q14247 CTTN	2	CTTN [cytosol] (R-HSA-201894) p-S113-CTTN [cytosol] (R-HSA-442842)	0.527	2
UniProt:P08050 Gja1	10	Cx43 [plasma membrane] (R-RNO-191661) Connexin 43 [Golgi membrane] (R-RNO-190650) Cx43 [endoplasmic reticulum membrane] (R-RNO-190688) Gja1 [Golgi membrane] (R-RNO-190649) Gja1 [endoplasmic reticulum membrane] (R-RNO-190654) Gja1 [lysosomal membrane] (R-RNO-196173) phospho-Gja1 [plasma membrane] (R-RNO-191657) Gja1 [plasma membrane] (R-RNO-158058) Cx43 [Golgi-associated vesicle membrane] (R-RNO-190646) Gja1 [Golgi-associated vesicle membrane] (R-RNO-190544)	0.489	2
UniProt:P60484 PTEN	20	K48polyUb-PTEN [cytosol] (R-HSA-8874327) PolyUb-PTEN [nucleoplasm] (R-HSA-6782515) PTEN H93R [cytosol] (R-HSA-2318524) PTEN C124R [cytosol] (R-HSA-2317439) PTEN H93Y [cytosol] (R-HSA-2318520) PTEN R130G [cytosol] (R-HSA-2317339) PTEN H93D [cytosol] (R-HSA-2318550) PTEN R130L [cytosol] (R-HSA-2317430) PTEN H93A [cytosol] (R-HSA-2318544) PTEN G129E [cytosol] (R-HSA-2318509) PTEN S170N [cytosol] (R-HSA-2318408) PTEN R173P [cytosol] (R-HSA-2317480) PTEN R130Q [cytosol] (R-HSA-2317416) PTEN H93Q [cytosol] (R-HSA-2318565) PTEN G129R [cytosol] (R-HSA-2318501) PTEN H123Y [cytosol] (R-HSA-2318469) PTEN S170R [cytosol] (R-HSA-2318437) PTEN R173C [cytosol] (R-HSA-2317478) PTEN R173H [cytosol] (R-HSA-2317473) PTEN C124S [cytosol] (R-HSA-2317379)	0.471	5

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