Reactome | RRAS2 [plasma membrane]

RRAS2 [plasma membrane]

Stable Identifier

R-HSA-9715189

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Ras-related protein R-Ras2 ecNumber evidence="14"3.6.5.-/ecNumber, RRAS2_HUMAN

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RND1 GTPase cycle (Homo sapiens)
        
        RND1 binds effectors (Homo sapiens)
        
        RND1 effectors [cytosol] (Homo sapiens)
        
        RRAS2 [plasma membrane] (Homo sapiens)
        
        RND1:GTP:RND1 effectors [plasma membrane] (Homo sapiens)
        
        RND1 effectors [cytosol] (Homo sapiens)
        
        RRAS2 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P62070 RRAS2

Gene Names

RRAS2, TC21

Chain

initiator methionine:, chain:2-201, propeptide:202-204

Reference Genes

BioGPS Gene:22800 RRAS2

COSMIC (genes):RRAS2 RRAS2

CTD Gene:22800 RRAS2

dbSNP Gene:22800 RRAS2

ENSEMBL:ENSG00000133818 RRAS2

ENSEMBL_homo_sapiens_GENE:ENSG00000133818.14 RRAS2

HGNC:17271 RRAS2

KEGG Gene (Homo sapiens):22800 RRAS2

Monarch:22800 RRAS2

NCBI Gene:22800 RRAS2

OMIM:600098 RRAS2

UCSC:P62070 RRAS2

Reference Transcript

Other Identifiers

11720721_s_at

11747262_s_at

11757492_s_at

16735994

1837_at

1838_g_at

208456_PM_s_at

208456_s_at

212589_PM_at

212589_at

212590_PM_at

212590_at

22800

2413090

2413092

2413094

2413095

2413096

32827_at

3363871

3363872

3363873

3363874

3363875

3363877

3363881

3363882

3363883

3363895

3363896

3363897

3363898

3363899

3363900

3363901

7946697

A_23_P405761

A_33_P3297245

GE61483

GE81777

GO:0000139

GO:0000166

GO:0001649

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005576

GO:0005615

GO:0005783

GO:0005794

GO:0005886

GO:0005925

GO:0007165

GO:0007265

GO:0016020

GO:0016477

GO:0016787

GO:0019003

GO:0023052

GO:0030154

GO:0036135

GO:0043226

GO:0048856

GO:0048870

GO:0070062

GO:1900149

HMNXSV003011987

Hs.206097.0.S1_3p_at

Hs.206097.0.S2_3p_at

ILMN_1667519

ILMN_2077623

TC01002663.hg

TC11001442.hg

g6912697_3p_a_at

Participates

as a candidate of

RND1 effectors [cytosol] (Homo sapiens)

Inferred To

wu:fc47b08 [plasma membrane] (Danio rerio)

rras2 [plasma membrane] (Xenopus tropicalis)

Rras2 [plasma membrane] (Rattus norvegicus)

RRAS2 [plasma membrane] (Bos taurus)

RRAS2 [plasma membrane] (Canis familiaris)

RRAS2 [plasma membrane] (Gallus gallus)

RRAS2 [plasma membrane] (Mus musculus)

RRAS2 [plasma membrane] (Saccharomyces cerevisiae)

RRAS2 [plasma membrane] (Schizosaccharomyces pombe)

RRAS2 [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_001096139.1, NP_001170785.1, NP_001170786.1, NP_036382.2

OpenTargets

ENSG00000133818

GeneCards

P62070

HPA

ENSG00000133818-RRAS2

Ensembl

ENST00000414023, ENSP00000433230, ENSP00000403282, ENSP00000256196, ENST00000537760, ENST00000256196, ENST00000532814, ENSP00000437083, ENST00000526063, ENST00000534746, ENSG00000133818, ENSP00000434104, ENSP00000431954, ENST00000529237, ENSP00000437547

PRO

P62070

Pharos - Targets

P62070

PDB

2ERY

HMDB Protein

HMDBP08569

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q04631	3	Fnta [cytosol] (R-RNO-202872) Fnta [cytosol] (R-RNO-202869) Fnta [cytosol] (R-RNO-2530516)	0.589	5