Reversible DNA damage induced by alkylating chemotherapeutic drugs

Stable Identifier
R-HSA-9729902
DOI
10.3180/R-HSA-9729902.1
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Reversible DNA damage induced by alkylating chemotherapeutic drugs
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This pathway describes how chemotherapeutic drugs commonly used in cancer treatment produce alkylating DNA damage that is repaired through the DNA damage reversal pathway. For review, please refer to Fu et al. 2012.
Literature References
PubMed ID Title Journal Year
22237395 Balancing repair and tolerance of DNA damage caused by alkylating agents

Fu, D, Samson, LD, Calvo, JA

Nat. Rev. Cancer 2012
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Authored
Orlic-Milacic, M  (2021-05-28)
Reviewed
Kadambat Nair, S  (2021-07-28)
Created
Orlic-Milacic, M  (2021-05-04)
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