Bile salts bind FABP6

Stable Identifier
R-HSA-9733973
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Bile salts bind FABP6
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Cytosolic ileal bile acid binding protein (IBABP, FABP6) (Fujita et al. 1995) mediates the intracellular binding and movement of bile acids (Kurz et al. 2003) to the basolateral membrane where organic solute transporters (OSTs) export bile acids and salts into the portal circulation to be returned to the liver.
Literature References
PubMed ID Title Journal Year
12486725 Insights into the bile acid transportation system: the human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures

Thüring, H, Matter, H, Stengelin, S, Kurz, M, Brachvogel, V, Kramer, W

Proteins 2003
7588781 Molecular cloning, expression, and characterization of a human intestinal 15-kDa protein

Fujita, M, Hatakeyama, K, Sato, E, Fujii, H, Ono, T, Kanda, T

Eur J Biochem 1995
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Orthologous Events
Bile salts bind FABP6 (Bos taurus)
Bile salts bind FABP6 (Caenorhabditis elegans)
Bile salts bind FABP6 (Danio rerio)
Bile salts bind FABP6 (Drosophila melanogaster)
Bile salts bind FABP6 (Gallus gallus)
Bile salts bind FABP6 (Mus musculus)
Bile salts bind FABP6 (Rattus norvegicus)
Bile salts bind FABP6 (Sus scrofa)
Bile salts bind FABP6 (Xenopus tropicalis)
Authored
Jassal, B  (2021-06-14)
Reviewed
D'Eustachio, P  (2021-06-21)
Created
Jassal, B  (2021-06-14)
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