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MyD88 complexed with the activated TLR receptor [endosome membrane]
Stable Identifier
R-HSA-975124
Type
Complex
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1,
Influenza A virus,
Human SARS coronavirus,
Severe acute respiratory syndrome coronavirus 2
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
MyD88 interacts with the activated TLR receptor 7, 8 or 9 (Homo sapiens)
MyD88 complexed with the activated TLR receptor [endosome membrane] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 (Homo sapiens)
MyD88 complexed with the activated TLR receptor [endosome membrane] (Homo sapiens)
Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
MyD88 interacts with the activated TLR receptor 7, 8 or 9 (Homo sapiens)
MyD88 complexed with the activated TLR receptor [endosome membrane] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 (Homo sapiens)
MyD88 complexed with the activated TLR receptor [endosome membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
19079358
TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA
Blum, LK
,
Cameron, JL
,
Brooks, JC
,
Chockalingam, A
,
Leifer, CA
Immunol Cell Biol
2009
Participants
components
Activated TLR7-9 homodimers [endosome membrane]
(Homo sapiens)
MYD88 homodimer [endosome membrane]
(Homo sapiens)
Participates
as an output of
MyD88 interacts with the activated TLR receptor 7, 8 or 9 (Homo sapiens)
as an input of
MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 (Homo sapiens)
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