Addition of a GlcNAc on the alpha 1,4 branch by MGAT2

Stable Identifier
R-HSA-975829
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The addition of a GlcNAc on the alpha-1,6 mannose on the alpha-1,4 branch is required for the synthesis of complex N-glycans (Tan et al. 1995). Defects in this gene are associated with Congenital Disorder of Glycosylation type IIa (Tan et al. 1996, Wang et al. 2002).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity of MGAT2 [Golgi membrane]
Physical Entity
Activity
Orthologous Events
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Reviewed
Created