Reactome | RNF19B [cytosol]

RNF19B [cytosol]

Stable Identifier

R-HSA-975969

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

E3 ubiquitin-protein ligase RNF19B, RN19B_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6ZMZ0 RNF19B

Gene Names

RNF19B, IBRDC3, NKLAM

Chain

chain:1-732

Reference Genes

BioGPS Gene:127544 RNF19B

COSMIC (genes):RNF19B RNF19B

CTD Gene:127544 RNF19B

dbSNP Gene:127544 RNF19B

ENSEMBL:ENSG00000116514 RNF19B

ENSEMBL:ENSG00000116514.17 RNF19B

HGNC:26886 RNF19B

KEGG Gene (Homo sapiens):127544 RNF19B

Monarch:127544 RNF19B

NCBI Gene:127544 RNF19B

OMIM:610872 RNF19B

UCSC:Q6ZMZ0 RNF19B

Reference Transcript

Other Identifiers

11725917_s_at

127544

16684812

213038_PM_at

213038_at

2405317

2405318

2405319

2405320

2405321

2405322

2405323

2405324

2405326

2405327

2405328

2405329

2405330

2405331

2405338

2405339

2405340

2405341

2405342

2405343

36564_PM_at

36564_at

7914603

A_23_P321388

GO:0000151

GO:0000209

GO:0002250

GO:0002376

GO:0003824

GO:0004842

GO:0005515

GO:0005737

GO:0005764

GO:0005773

GO:0005783

GO:0005789

GO:0005829

GO:0006511

GO:0016020

GO:0016567

GO:0016740

GO:0030163

GO:0031624

GO:0032436

GO:0036211

GO:0042267

GO:0043130

GO:0043226

GO:0044194

GO:0046872

GO:0051865

GO:0061630

GO:0098542

GO:0140096

HMNXSV003028799

HMNXSV003049215

Hs.64239.0.A1_3p_at

Hs.64239.0.A1_3p_s_at

ILMN_1682081

PH_hs_0026633

TC01002478.hg

Participates

as a member of

E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)

Inferred To

Rnf19b [cytosol] (Rattus norvegicus)

RNF19B [cytosol] (Bos taurus)

RNF19B [cytosol] (Caenorhabditis elegans)

RNF19B [cytosol] (Danio rerio)

RNF19B [cytosol] (Dictyostelium discoideum)

RNF19B [cytosol] (Mus musculus)

RNF19B [cytosol] (Saccharomyces cerevisiae)

RNF19B [cytosol] (Sus scrofa)

fj68f04 [cytosol] (Danio rerio)

Homologues of RNF19B [cytosol] (Caenorhabditis elegans)

Homologues of RNF19B [cytosol] (Danio rerio)

Homologues of RNF19B [cytosol] (Dictyostelium discoideum)

rnf19b [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

XP_006710419.1, NP_001120833.1, NP_699172.2, NP_001287755.1

OpenTargets

ENSG00000116514

GeneCards

Q6ZMZ0

HPA

ENSG00000116514-RNF19B

Ensembl

ENST00000373456, ENST00000235150, ENST00000356990, ENSP00000235150, ENSG00000116514, ENSP00000349482, ENSP00000362555

PRO

Q6ZMZ0

Pharos - Targets

Q6ZMZ0

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NWZ5 UCKL1	1	UCKL1 [cytosol] (R-HSA-8954322)	0.602	4
UniProt:P01375 TNF	5	TNF(52-76) [extracellular region] (R-HSA-8863375) TNF(1-34) [plasma membrane] (R-HSA-8863367) TNF(1-76) [plasma membrane] (R-HSA-8863120) TNF(77-233) [extracellular region] (R-HSA-976821) TNF(1-233) [plasma membrane] (R-HSA-66220)	0.556	3
UniProt:P14324 FDPS	1	FDPS [cytosol] (R-HSA-981566)	0.556	3
UniProt:O14653 GOSR2	4	GOSR2 [endoplasmic reticulum membrane] (R-HSA-5689451) GOSR2 [ER to Golgi transport vesicle membrane] (R-HSA-5689800) GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-535472) GOSR2 [Golgi membrane] (R-HSA-6807755)	0.556	3
UniProt:Q15436 SEC23A	4	p-S738,T744 SEC23A [cytosol] (R-HSA-5685740) SEC23A [ER to Golgi transport vesicle membrane] (R-HSA-204024) SEC23A [cytosol] (R-HSA-203972) SEC23A [endoplasmic reticulum membrane] (R-HSA-203976)	0.556	3
UniProt:Q9NTJ5 SACM1L	2	SACM1L [endoplasmic reticulum membrane] (R-HSA-1604637) SACM1L [Golgi membrane] (R-HSA-1806242)	0.556	3
UniProt:P68036 UBE2L3	4	Ub-C86-UBE2L3 [nucleoplasm] (R-HSA-8864226) UBE2L3 [nucleoplasm] (R-HSA-8852056) Ub-C86-UBE2L3 [cytosol] (R-HSA-8864201) UBE2L3 [cytosol] (R-HSA-947631)	0.524	2
UniProt:O14933 UBE2L6	2	UBE2L6 [cytosol] (R-HSA-936014) UBE2L6 [nucleoplasm] (R-HSA-5653666)	0.524	3

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