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MGRN1 [cytosol]
Stable Identifier
R-HSA-975971
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase MGRN1, MGRN1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
MGRN1 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
MGRN1 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
MGRN1 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
MGRN1 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
MGRN1 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
MGRN1 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
MGRN1 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
MGRN1 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
MGRN1 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
MGRN1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60291 MGRN1
Gene Names
MGRN1, KIAA0544, RNF156
Chain
initiator methionine:, chain:2-552
Reference Genes
BioGPS Gene:23295 MGRN1
COSMIC (genes):MGRN1 MGRN1
CTD Gene:23295 MGRN1
dbSNP Gene:23295 MGRN1
ENSEMBL:ENSG00000102858 MGRN1
ENSEMBL_homo_sapiens_GENE:ENSG00000102858.13 MGRN1
HGNC:20254 MGRN1
Monarch:23295 MGRN1
NCBI Gene:23295 MGRN1
OMIM:607559 MGRN1
UCSC:O60291 MGRN1
Reference Transcript
RefSeq:NM_001142290.2 MGRN1
RefSeq:NM_015246.3 MGRN1
RefSeq:NM_001142291.2 MGRN1
RefSeq:XM_005255220.3 MGRN1
RefSeq:NM_001142289.2 MGRN1
RefSeq:XM_005255221.3 MGRN1
Other Identifiers
11717325_at
11721067_s_at
16815557
16815579
212576_PM_at
212576_at
224477_PM_s_at
224477_s_at
23295
32235_at
3646279
3646280
3646289
3646291
3646292
3646293
3646299
3646301
3646302
3646304
3646306
3646309
3646312
3646313
3646314
3646316
3646318
3646321
3646322
3646323
3646324
3646325
3646326
3646327
3646328
3646329
3646330
3646331
3646332
3646333
3646334
3646335
3646336
3646337
3646338
3646339
3646340
3646342
3646344
3646346
3646347
3646348
3646350
3646351
3646352
3646353
3646354
3646355
3646356
3646357
54092_at
7992998
7993019
A_23_P355824
A_23_P49429
A_24_P399065
A_33_P3407657
GE53268
GE83389
GO:0000209
GO:0003824
GO:0004842
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005768
GO:0005769
GO:0005783
GO:0005829
GO:0005886
GO:0006513
GO:0008333
GO:0016020
GO:0016192
GO:0016567
GO:0016740
GO:0023052
GO:0031410
GO:0036211
GO:0043226
GO:0043231
GO:0043951
GO:0045744
GO:0045879
GO:0046872
GO:0061630
GO:0070062
GO:0140096
HMNXSV003003368
HMNXSV003012974
HMNXSV003016652
HMNXSV003030199
Hs.284251.0.S1_3p_at
ILMN_1735415
ILMN_1745697
PH_hs_0024516
TC16000133.hg
TC16000134.hg
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
mgrn-1 [cytosol]
(Caenorhabditis elegans)
Dmel\CG2617 [cytosol]
(Drosophila melanogaster)
MGRN1 [cytosol]
(Bos taurus)
MGRN1 [cytosol]
(Canis familiaris)
MGRN1 [cytosol]
(Danio rerio)
MGRN1 [cytosol]
(Dictyostelium discoideum)
MGRN1 [cytosol]
(Gallus gallus)
MGRN1 [cytosol]
(Plasmodium falciparum)
MGRN1 [cytosol]
(Sus scrofa)
Homologues of MGRN1 [cytosol]
(Drosophila melanogaster)
Homologues of MGRN1 [cytosol]
(Plasmodium falciparum)
Mgrn1 [cytosol]
(Mus musculus)
Mgrn1 [cytosol]
(Rattus norvegicus)
Mrgn1 [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
XP_005255278.1
,
NP_056061.1
,
NP_001135763.2
,
NP_001135761.2
,
XP_005255277.1
,
NP_001135762.1
OpenTargets
ENSG00000102858
GeneCards
O60291
HPA
ENSG00000102858-MGRN1
Ensembl
ENSP00000393311
,
ENST00000262370
,
ENST00000399577
,
ENSP00000382487
,
ENSP00000465860
,
ENST00000415496
,
ENSP00000468819
,
ENST00000586183
,
ENST00000588994
,
ENSP00000262370
,
ENSG00000102858
PRO
O60291
Pharos - Targets
O60291
HMDB Protein
HMDBP09273
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