Reactome: A Curated Pathway Database

ITCH

Stable Identifier
R-HSA-975995
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
E3 ubiquitin-protein ligase Itchy homolog, ITCH_HUMAN, AIP4
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
ITCH
Chain
initiator methionine:1, chain:2-903
Reference Genes
Reference Transcript
Other Identifiers
 0003440280  11731493_at  11731494_a_at  11745275_x_at  11749666_a_at
 16912905  209743_s_at  209744_x_at  21126  217094_s_at
 235057_at  239101_at  2DMV  2KYK  2NQ3
 2P4R  2YSF  38349_at  3882855  3882858
 3882862  3882863  3882867  3882871  3882873
 3882875  3882877  3882884  3882885  3882886
 3882887  3882889  3882891  3882892  3882893
 3882898  3882901  3882906  3882909  3882910
 3882911  3882912  3882915  3882917  3882918
 3882921  3882923  3882924  3882925  3882926
 3882927  3882928  3882929  3TUG  46555_at
 49032  4ROF  5C7M  5CQ2  5DWS
 5DZD  5SXP  74663_s_at  74996_at  76200_r_at
 8061986  83737  A_14_P109028  A_14_P128989  A_23_P132019
 A_24_P139191  AAC04845  AAH06848  AAH11571  AAK39399
 AB056663  AF038564  AF095745  AK304090  AK315212
 AL109923  AL356299  BAB39389  BAG37647  BAG64996
 BC006848  BC011571  CAI17959  CAI17960  CAI21458
 CAI21459  CCDS13234  CCDS58768  CCDS58769  CH471077
 EAW76272  EAW76274  EAW76276  ENSG00000078747  ENSP00000262650
 ENSP00000363998  ENSP00000445608  ENST00000262650  ENST00000374864  ENST00000535650
 EntrezGene:83737  GE61516  GO:0000209  GO:0001558  GO:0002376
 GO:0002669  GO:0003674  GO:0004842  GO:0005515  GO:0005575
 GO:0005576  GO:0005622  GO:0005623  GO:0005634  GO:0005654
 GO:0005737  GO:0005829  GO:0005886  GO:0005938  GO:0006464
 GO:0006511  GO:0006915  GO:0006950  GO:0006954  GO:0007155
 GO:0007165  GO:0007219  GO:0008150  GO:0008219  GO:0008283
 GO:0009056  GO:0009058  GO:0016020  GO:0016032  GO:0016567
 GO:0016740  GO:0016874  GO:0019787  GO:0031410  GO:0032088
 GO:0032480  GO:0034641  GO:0035519  GO:0040007  GO:0042787
 GO:0043021  GO:0043066  GO:0043226  GO:0044403  GO:0045087
 GO:0045236  GO:0045732  GO:0046329  GO:0046642  GO:0046718
 GO:0048856  GO:0050687  GO:0051607  GO:0061630  GO:0070062
 GO:0070423  GO:0070534  GO:0070936  GO:0090085  HGNC:13890
 HPA021126  HPA049032  Hs.120212.0.A1_3p_at  Hs.134350.0.A1_3p_at  Hs.98074.0.S1_3p_a_at
 Hs.98074.1.S1_3p_a_at  ILMN_1752283  IPR000008  IPR000569  IPR001202
 IPR024928  ITCH  ITCH-201  ITCH-202  ITCH-207
 LRG_354  NM_001257137  NM_001257138  NM_001324197  NM_001324198
 NM_031483  NP_001244066  NP_001244067  NP_001311126  NP_001311127
 NP_113671  PF00168  PF00397  PF00632  PH_hs_0023754
 SM00119  SM00239  SM00456  TC20000239.hg  uc002xak.3
 uc010geu.3  uc061wip.1  UPI000007199B  UPI00000731C2  UPI00004AE2D2
 XM_005260570  XM_011529079  XM_017028089  XM_017028090  XM_017028091
 XP_005260627  XP_011527381  XP_016883578  XP_016883579  XP_016883580
 XR_001754418
Participant Of
Inferred To
Cross References
UCSC human
GeneCards
DOCK Blaster
PRO
Orphanet
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.645 Q96BR1 SGK3_HUMAN 5
0.639 O15350-1 TP73 5
0.623 Q9Y5X1 SNX9_HUMAN 7
0.602 P08151 GLI1_HUMAN 4
0.602 Q9ULV8 CBLC_HUMAN 5
0.59 P13285 LMP2_EBVB9 3
0.581 Q14511 CASL_HUMAN 3
0.571 Q9BTU6 P4K2A_HUMAN 5
0.544 Q9Y3C5 RNF11_HUMAN 2
0.526 Q99962 SH3G2_HUMAN 3
0.524 P70444 BID_MOUSE 2
0.524 Q9QZS3-2 NUMB 2
0.482 Q96B67 ARRD3_HUMAN 2
0.463 Q9EPK8 TRPV4_MOUSE 2
0.463 Q86Y01 DTX1_HUMAN 2