ITCH [cytosol]

Stable Identifier
R-HSA-975995
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase Itchy homolog, ITCH_HUMAN, AIP4
Locations in the PathwayBrowser for interactor UniProt:Q96B67
Expand all
External Reference Information
External Reference
UniProt:Q96J02 ITCH
Gene Names
ITCH
Chain
initiator methionine:1, chain:2-903
Reference Genes
BioGPS Gene:83737 ITCH
COSMIC (genes):ITCH ITCH
CTD Gene:83737 ITCH
dbSNP Gene:83737 ITCH
ENSEMBL:ENSG00000078747 ITCH
HGNC:13890 ITCH
KEGG Gene (Homo sapiens):83737 ITCH
Monarch:83737 ITCH
NCBI Gene:83737 ITCH
OMIM:606409 ITCH
UCSC:Q96J02 ITCH
Reference Transcript
Other Identifiers
0003440280
11731493_at
11731494_a_at
11745275_x_at
11749666_a_at
16912905
209743_s_at
209744_x_at
217094_s_at
235057_at
239101_at
38349_at
3882855
3882858
3882862
3882863
3882867
3882871
3882873
3882875
3882877
3882884
3882885
3882886
3882887
3882889
3882891
3882892
3882893
3882898
3882901
3882906
3882909
3882910
3882911
3882912
3882915
3882917
3882918
3882921
3882923
3882924
3882925
3882926
3882927
3882928
3882929
3882946
3882948
46555_at
74663_s_at
74996_at
76200_r_at
8061986
83737
88659_at
A_14_P109028
A_14_P121685
A_14_P128989
A_23_P132019
A_24_P139191
GE61516
GO:0000209
GO:0001558
GO:0002376
GO:0003674
GO:0004842
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005768
GO:0005769
GO:0005829
GO:0005886
GO:0006464
GO:0006511
GO:0006915
GO:0006950
GO:0006954
GO:0007165
GO:0007219
GO:0008150
GO:0008219
GO:0009056
GO:0009058
GO:0010008
GO:0016020
GO:0016032
GO:0016567
GO:0016740
GO:0019899
GO:0030154
GO:0031410
GO:0031901
GO:0032088
GO:0032480
GO:0032991
GO:0034641
GO:0035519
GO:0040007
GO:0043021
GO:0043066
GO:0043161
GO:0043226
GO:0043231
GO:0044389
GO:0044403
GO:0045087
GO:0045236
GO:0045732
GO:0046329
GO:0046718
GO:0048856
GO:0050687
GO:0051607
GO:0051865
GO:0061630
GO:0070062
GO:0070423
GO:0070534
GO:0070936
GO:0090085
GO:1902036
GO:1990763
GO:2000646
HMNXSV003038485
HMNXSV003044003
Hs.120212.0.A1_3p_at
Hs.134350.0.A1_3p_at
Hs.98074.0.S1_3p_a_at
Hs.98074.1.S1_3p_a_at
ILMN_1752283
PH_hs_0023754
TC20000239.hg
Participates
as a component of
as an input of
as an output of
as a member of
as a candidate of
Inferred To
ITCH [cytosol] (Canis familiaris)
ITCH [cytosol] (Dictyostelium discoideum)
ITCH [cytosol] (Gallus gallus)
ITCH [cytosol] (Plasmodium falciparum)
ITCH [cytosol] (Sus scrofa)
pub1 [cytosol] (Schizosaccharomyces pombe)
RSP5 [cytosol] (Saccharomyces cerevisiae)
Su(dx) [cytosol] (Drosophila melanogaster)
itchb [cytosol] (Danio rerio)
pub3 [cytosol] (Schizosaccharomyces pombe)
wwp-1 [cytosol] (Caenorhabditis elegans)
Homologues of ITCH [cytosol] (Dictyostelium discoideum)
Homologues of ITCH [cytosol] (Schizosaccharomyces pombe)
Itch [cytosol] (Mus musculus)
Itch [cytosol] (Rattus norvegicus)
pub2 [cytosol] (Schizosaccharomyces pombe)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Orphanet
PDB
Interactors (20)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:O15350 TP73  3 0.656 3
 UniProt:Q96BR1 SGK3  1 0.645 5
 UniProt:O15350-1 TP73      0.639 5
 UniProt:Q9Y5X1 SNX9  3 0.623 7
 UniProt:Q96B67 ARRD3      0.613 3
 UniProt:Q9ULV8 CBLC      0.602 5
 UniProt:P08151 GLI1  9 0.602 4
 UniProt:O75113 N4BP1      0.591 3
 UniProt:P13285 LMP2      0.59 3
 UniProt:Q14511 CASL      0.581 3
 UniProt:Q9BTU6 PI4K2A  1 0.571 5
 UniProt:Q8N5I2 ARRD1      0.547 2
 UniProt:Q9Y3C5 RNF11      0.544 2
 UniProt:Q8N0X7 SPART      0.527 2
 UniProt:Q99962 SH3GL2  4 0.526 3
 UniProt:Q9QZS3-2 NUMB      0.524 2
 UniProt:Q9H3D4 TP63  1 0.499 2
 UniProt:P70444  4 0.471 2
 UniProt:Q86Y01 DTX1  1 0.463 2
 UniProt:Q9EPK8  1 0.463 2
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