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RNF34 [cytosol]
Stable Identifier
R-HSA-975998
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase RNF34, RNF34_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF34 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF34 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF34 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF34 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF34 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF34 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF34 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF34 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF34 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF34 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q969K3 RNF34
Gene Names
RNF34
Chain
chain:1-372
Reference Genes
BioGPS Gene:80196 RNF34
COSMIC (genes):RNF34 RNF34
CTD Gene:80196 RNF34
dbSNP Gene:80196 RNF34
ENSEMBL:ENSG00000170633 RNF34
HGNC:17297 RNF34
KEGG Gene (Homo sapiens):80196 RNF34
Monarch:80196 RNF34
NCBI Gene:80196 RNF34
OMIM:608299 RNF34
UCSC:Q969K3 RNF34
Reference Transcript
RefSeq:NM_001256858.1 RNF34
RefSeq:NM_025126.3 RNF34
RefSeq:NM_194271.2 RNF34
Other Identifiers
0006620484
0006840520
11717384_a_at
16758107
219035_PM_s_at
219035_s_at
3434824
3434825
3434832
3434836
3434837
3434838
3434839
3434844
3434847
3434851
3434852
3434853
3434854
46229_at
7959282
80196
A_14_P119505
A_23_P128396
A_24_P278839
GE87752
GO:0002039
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0006464
GO:0006511
GO:0006915
GO:0006950
GO:0007165
GO:0008150
GO:0008219
GO:0008289
GO:0009056
GO:0012505
GO:0016020
GO:0016567
GO:0016604
GO:0016607
GO:0016740
GO:0019899
GO:0031625
GO:0035872
GO:0043161
GO:0043167
GO:0043226
GO:0046872
GO:0061630
GO:0070417
GO:0070936
GO:1901796
GO:1901797
GO:1901981
GO:1902042
GO:2000374
GO:2001271
HMNXSV003015741
ILMN_1682988
ILMN_1786039
ILMN_2398664
PH_hs_0029655
TC12000958.hg
g13376704_3p_s_at
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Other forms of this molecule
RNF34 [nucleoplasm]
Inferred To
rnf34a [cytosol]
(Danio rerio)
Homologues of RNF34 [cytosol]
(Dictyostelium discoideum)
RNF34 [cytosol]
(Bos taurus)
RNF34 [cytosol]
(Canis familiaris)
RNF34 [cytosol]
(Dictyostelium discoideum)
RNF34 [cytosol]
(Gallus gallus)
RNF34 [cytosol]
(Sus scrofa)
cblA-1 [cytosol]
(Dictyostelium discoideum)
Rnf34 [cytosol]
(Mus musculus)
Rnf34 [cytosol]
(Rattus norvegicus)
dRNF34 [cytosol]
(Drosophila melanogaster)
rnf34 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001243787.1
,
NP_919247.1
,
NP_079402.2
OpenTargets
ENSG00000170633
IntEnz
2.3.2.27
HPA
ENSG00000170633-RNF34
GeneCards
Q969K3
Ensembl
ENSG00000170633
,
ENSP00000355137
,
ENST00000361234
,
ENSP00000376258
,
ENST00000392465
PRO
Q969K3
Pharos - Targets
Q969K3
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q53GS7 GLE1
1
GLE1 [nucleoplasm]
(R-HSA-8932905)
0.556
3
UniProt:Q14790 CASP8
8
CASP8(1-374) [cytosol]
(R-HSA-3465404)
CASP8(217-374) [mitochondrial outer membrane]
(R-HSA-351869)
CASP8(385-479) [mitochondrial outer membrane]
(R-HSA-351828)
CASP8(385-479) [cytosol]
(R-HSA-76158)
CASP8(375-384) [cytosol]
(R-HSA-933460)
CASP8(217-374) [cytosol]
(R-HSA-75975)
CASP8(1-216) [cytosol]
(R-HSA-933456)
CASP8(1-479) [cytosol]
(R-HSA-57031)
0.508
3
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