Reactome | RNF138 [cytosol]

RNF138 [cytosol]

Stable Identifier

R-HSA-976008

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

E3 ubiquitin-protein ligase RNF138, RN138_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8WVD3 RNF138

Gene Names

RNF138, NARF, HSD-4, HSD4

Chain

initiator methionine:1, chain:2-245

Reference Genes

BioGPS Gene:51444 RNF138

COSMIC (genes):RNF138 RNF138

CTD Gene:51444 RNF138

dbSNP Gene:51444 RNF138

ENSEMBL:ENSG00000134758 RNF138

HGNC:17765 RNF138

KEGG Gene (Homo sapiens):51444 RNF138

Monarch:51444 RNF138

NCBI Gene:51444 RNF138

OMIM:616319 RNF138

UCSC:Q8WVD3 RNF138

Reference Transcript

Other Identifiers

0002030010

0002450446

11723230_a_at

11723231_s_at

11723232_x_at

11758333_s_at

16851810

218738_s_at

239143_3p_x_at

239143_x_at

2857251

2857252

3783750

3783751

3783752

3783759

3783760

3783761

3783766

3783767

3783768

3783769

3783771

3783772

3783773

3783774

48569_at

48570_at

50567_r_at

51444

8020814

A_23_P89755

A_24_P202512

GE62688

GO:0000724

GO:0003674

GO:0003677

GO:0003697

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005694

GO:0006259

GO:0006281

GO:0006464

GO:0006950

GO:0006974

GO:0007165

GO:0007267

GO:0008150

GO:0008270

GO:0010792

GO:0016055

GO:0016567

GO:0016740

GO:0019899

GO:0019901

GO:0034641

GO:0035861

GO:0043167

GO:0043226

GO:0046872

GO:0061630

Hs.122139.0.A1_3p_at

Hs.122139.0.A1_3p_s_at

Hs.122139.0.A1_3p_x_at

ILMN_1655165

ILMN_1742806

PH_hs_0029343

TC18000133.hg

g7706722_3p_a_at

Participant Of

hasCandidate

E3 ligases in proteasomal degradation [cytosol]

Inferred To

RNF138 [cytosol] (Bos taurus)

RNF138 [cytosol] (Canis familiaris)

RNF138 [cytosol] (Gallus gallus)

RNF138 [cytosol] (Sus scrofa)

rnf138 [cytosol] (Xenopus tropicalis)

Rnf138 [cytosol] (Mus musculus)

Cross References

RefSeq

XP_005258343.1, NP_001178253.2, NP_057355.2, NP_937761.1

OpenTargets

ENSG00000134758

GeneCards

Q8WVD3

HPA

ENSG00000134758-RNF138

Ensembl

ENST00000261593, ENST00000257190, ENSP00000261593, ENSP00000257190, ENSG00000134758

PRO

Q8WVD3

HMDB Protein

HMDBP11561

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P37840 SNCA	4	SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569) SNCA [cytosol] (R-HSA-5658500) Ub-SNCA [cytosol] (R-HSA-5660754)	0.556	3
UniProt:P06396 GSN	7	GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(200-270) [extracellular region] (R-HSA-976940) GSN [extracellular region] (R-HSA-6806510) GSN [secretory granule lumen] (R-HSA-6801486) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:Q14957 GRIN2C	3	p-Y-GRIN2C [plasma membrane] (R-HSA-9612189) GRIN2C [plasma membrane] (R-HSA-419560) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761)	0.556	3
UniProt:P07550 ADRB2	5	ADRB2 [endosome membrane] (R-HSA-6783036) pS-ADRB2 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869143) PolyUb-ADRB2 [endosome membrane] (R-HSA-6783066) pS-ADRB2 [plasma membrane] (R-HSA-8852158) ADRB2 [plasma membrane] (R-HSA-390647)	0.556	3
UniProt:P02545 LMNA	3	LMNA-RAF1 fusion [cytosol] (R-HSA-6802399) LMNA(1-664) [nucleoplasm] (R-HSA-535479) p-LMNA-RAF1 fusion [cytosol] (R-HSA-6802537)	0.556	3