Reactome | MID1 [cytosol]

MID1 [cytosol]

Stable Identifier

R-HSA-976027

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Midline-1, TRI18_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O15344 MID1

Gene Names

MID1, FXY, RNF59, TRIM18, XPRF

Chain

chain:1-667

Reference Genes

BioGPS Gene:4281 MID1

COSMIC (genes):MID1 MID1

CTD Gene:4281 MID1

dbSNP Gene:4281 MID1

ENSEMBL:ENSG00000101871 MID1

HGNC:7095 MID1

KEGG:hsa:4281 MID1

Monarch:4281 MID1

NCBI Gene:4281 MID1

OMIM:300552 MID1

UCSC:O15344 MID1

Reference Transcript

Other Identifiers

11721888_a_at

11745148_a_at

11752289_a_at

11756082_a_at

11758203_s_at

17109042

203636_PM_at

203636_at

203637_PM_s_at

203637_s_at

34296_at

3999397

3999398

3999399

3999400

3999401

3999402

3999403

3999405

3999406

3999407

3999409

3999410

3999411

3999412

3999413

3999419

3999420

3999421

3999426

3999427

3999437

3999438

3999439

3999440

3999441

3999442

3999443

3999444

3999448

3999450

3999451

3999453

3999462

3999463

3999472

3999490

3999491

4281

8171297

A_21_P0000116

A_21_P0000117

A_23_P170037

A_32_P128656

GE540607

GE54356

GE546443

GO:0000226

GO:0003824

GO:0005515

GO:0005737

GO:0005794

GO:0005819

GO:0005829

GO:0005856

GO:0005874

GO:0005875

GO:0005881

GO:0007010

GO:0007026

GO:0007389

GO:0008017

GO:0008092

GO:0008270

GO:0015630

GO:0016020

GO:0016740

GO:0019899

GO:0031625

GO:0032874

GO:0034451

GO:0035372

GO:0042802

GO:0042803

GO:0043226

GO:0046872

GO:0051219

GO:0070507

HMNXSV003001732

HMNXSV003023002

HMNXSV003026722

HMNXSV003048940

Hs.27695.0.A2_3p_at

ILMN_1761858

ILMN_2371433

PH_hs_0002447

TC0X001976.hg

TC0X001978.hg

g4557752_3p_a_at

p26929

Participates

as a member of

IFNG induced TRIMs [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_000372.1, NP_001180206.1, NP_001180209.1, NP_001334662.1, NP_001180208.1, NP_001180207.1, NP_001180210.1, NP_150632.1, XP_016885029.1, NP_001092094.1, XP_016885025.1

OpenTargets

ENSG00000101871

ENSEMBL

ENST00000380785, ENST00000413894, ENSP00000370156, ENSP00000370157, ENST00000380782, ENST00000380780, ENSP00000370159, ENST00000380787, ENSP00000312678, ENST00000317552, ENST00000380779, ENSP00000370162, ENSP00000414521, ENST00000453318, ENSP00000391154, ENSP00000370164

HPA

ENSG00000101871-MID1

PRO

O15344

Pharos - Targets

O15344

Orphanet

MID1

PDB

7QRY, 2DQ5, 2FFW, 5IM8, 2JUN

HMDB Protein

HMDBP09282

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61077 UBE2D3	3	Ub-C85-UBE2D3 [cytosol] (R-HSA-8864191) UBE2D3 [cytosol] (R-HSA-934630) UBE2D3 [nucleoplasm] (R-HSA-205341)	0.83	8
UniProt:Q08426 EHHADH	2	EHHADH [peroxisomal matrix] (R-HSA-400155) EHHADH [cytosol] (R-HSA-9033147)	0.781	8
UniProt:P51668 UBE2D1	3	UBE2D1 [cytosol] (R-HSA-174236) UBE2D1 [nucleoplasm] (R-HSA-174197) Ub-C85-UBE2D1 [cytosol] (R-HSA-8864160)	0.781	7
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.666	4
UniProt:P68036 UBE2L3	4	Ub-C86-UBE2L3 [cytosol] (R-HSA-8864201) UBE2L3 [cytosol] (R-HSA-947631) UBE2L3 [nucleoplasm] (R-HSA-8852056) Ub-C86-UBE2L3 [nucleoplasm] (R-HSA-8864226)	0.666	4
UniProt:Q9HAQ2 KIF9	1	KIF9 [cytosol] (R-HSA-984616)	0.556	3
UniProt:O14933 UBE2L6	2	UBE2L6 [cytosol] (R-HSA-936014) UBE2L6 [nucleoplasm] (R-HSA-5653666)	0.556	3
UniProt:O75113 N4BP1	3	N4BP1(1-490) [cytosol] (R-HSA-9757922) N4BP1(1-424) [cytosol] (R-HSA-9757940) N4BP1 [cytosol] (R-HSA-9757941)	0.556	3
UniProt:Q49AN0 CRY2	4	p-S-CRY2 [cytosol] (R-HSA-400305) p-S-CRY2 [nucleoplasm] (R-HSA-400328) CRY2 [cytosol] (R-HSA-400255) Ub-p-S-CRY2 [nucleoplasm] (R-HSA-517935)	0.556	3
UniProt:Q16512 PKN1	3	p-T774-PKN1 [cytosol] (R-HSA-5623651) PKN1 [cytosol] (R-HSA-5623613) p-T774-PKN1 [nucleoplasm] (R-HSA-5625721)	0.556	3
UniProt:O75496 GMNN	2	GMNN [nucleoplasm] (R-HSA-113554) PolyUb-GMNN [nucleoplasm] (R-HSA-68585)	0.527	2

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