ZEB2 and SP1 bind CDH11 gene promoter

Stable Identifier
R-HSA-9761025
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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ZEB2 and SP1 bind CDH11 gene promoter
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ZEB2 (Zinc finger E-box-binding homeobox 2) and SP1 bind to the CDH11 gene promoter, most likely to the region located -191 to -62 nucleotides upstream from the transcription start site. Binding of ZEB2 is dependent on the presence of SP1-binding elements (Nam et al. 2014).
Literature References
PubMed ID Title Journal Year
24130169 ZEB2-Sp1 cooperation induces invasion by upregulating cadherin-11 and integrin α5 expression

Nam, EH, Kim, S, Park, YK, Zhao, XF, Lee, Y, Lee, JW

Carcinogenesis 2014
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as an event of
Authored
Orlic-Milacic, M  (2022-06-02)
Reviewed
Brasch, J  (2023-04-18)
Created
Orlic-Milacic, M  (2022-01-06)
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