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CHUK:IKBKB:IKBKG:USP18 [cytosol]
Stable Identifier
R-HSA-9761338
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Synonyms
USP18:IKK complex
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 signaling (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Regulation of NF-kappa B signaling (Homo sapiens)
USP18 binds IKBKG within IKK complex (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Ubiquitination of IKBKG by TRAF6 (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Regulation of NF-kappa B signaling (Homo sapiens)
USP18 binds IKBKG within IKK complex (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Ubiquitination of IKBKG by TRAF6 (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)
Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Regulation of NF-kappa B signaling (Homo sapiens)
USP18 binds IKBKG within IKK complex (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Ubiquitination of IKBKG by TRAF6 (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Regulation of NF-kappa B signaling (Homo sapiens)
USP18 binds IKBKG within IKK complex (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Ubiquitination of IKBKG by TRAF6 (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Regulation of NF-kappa B signaling (Homo sapiens)
USP18 binds IKBKG within IKK complex (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Ubiquitination of IKBKG by TRAF6 (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88-independent TLR4 cascade (Homo sapiens)
TRIF (TICAM1)-mediated TLR4 signaling (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Regulation of NF-kappa B signaling (Homo sapiens)
USP18 binds IKBKG within IKK complex (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Ubiquitination of IKBKG by TRAF6 (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Regulation of NF-kappa B signaling (Homo sapiens)
USP18 binds IKBKG within IKK complex (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Ubiquitination of IKBKG by TRAF6 (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Regulation of NF-kappa B signaling (Homo sapiens)
USP18 binds IKBKG within IKK complex (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Ubiquitination of IKBKG by TRAF6 (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Regulation of NF-kappa B signaling (Homo sapiens)
USP18 binds IKBKG within IKK complex (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Ubiquitination of IKBKG by TRAF6 (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Regulation of NF-kappa B signaling (Homo sapiens)
USP18 binds IKBKG within IKK complex (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Ubiquitination of IKBKG by TRAF6 (Homo sapiens)
CHUK:IKBKB:IKBKG:USP18 [cytosol] (Homo sapiens)
Participants
components
CHUK:IKBKB:IKBKG [cytosol]
(Homo sapiens)
USP18 [cytosol]
(Homo sapiens)
Participates
as an output of
USP18 binds IKBKG within IKK complex (Homo sapiens)
This entity regulates
Negatively
Ubiquitination of IKBKG by TRAF6
(Homo sapiens)
Inferred To
CHUK:IKBKB:IKBKG:USP18 [cytosol]
(Bos taurus)
CHUK:IKBKB:IKBKG:USP18 [cytosol]
(Canis familiaris)
CHUK:IKBKB:IKBKG:USP18 [cytosol]
(Drosophila melanogaster)
CHUK:IKBKB:IKBKG:USP18 [cytosol]
(Mus musculus)
CHUK:IKBKB:IKBKG:USP18 [cytosol]
(Rattus norvegicus)
CHUK:IKBKB:IKBKG:USP18 [cytosol]
(Sus scrofa)
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