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PRPF4B [nucleoplasm]
Stable Identifier
R-HSA-9769525
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Serine/threonine-protein kinase PRP4 homolog ecNumber2.7.11.1/ecNumber, PRP4B_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q15029 EFTUD2
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
PRPF4B [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
PRPF4B [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13523 PRPF4B
Gene Names
PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K, PRPF4K
Chain
initiator methionine:, chain:2-1007
Reference Genes
BioGPS Gene:8899 PRPF4B
COSMIC (genes):PRPF4B PRPF4B
CTD Gene:8899 PRPF4B
dbSNP Gene:8899 PRPF4B
ENSEMBL:ENSG00000112739 PRPF4B
ENSEMBL_homo_sapiens_GENE:ENSG00000112739.17 PRPF4B
HGNC:17346 PRPF4B
KEGG Gene (Homo sapiens):8899 PRPF4B
Monarch:8899 PRPF4B
NCBI Gene:8899 PRPF4B
OMIM:602338 PRPF4B
UCSC:Q13523 PRPF4B
Reference Transcript
RefSeq:NM_003913.4 PRPF4B
RefSeq:XM_017011418.1 PRPF4B
RefSeq:XM_017011426.1 PRPF4B
RefSeq:XM_017011421.1 PRPF4B
RefSeq:XM_017011413.1 PRPF4B
RefSeq:XM_017011424.1 PRPF4B
RefSeq:XM_017011416.1 PRPF4B
RefSeq:XM_017011430.1 PRPF4B
RefSeq:XM_017011431.1 PRPF4B
RefSeq:XM_017011427.1 PRPF4B
RefSeq:XM_017011410.1 PRPF4B
RefSeq:XM_017011419.1 PRPF4B
RefSeq:XM_017011411.1 PRPF4B
RefSeq:XM_017011422.1 PRPF4B
RefSeq:XM_017011414.1 PRPF4B
RefSeq:XM_017011417.1 PRPF4B
RefSeq:XM_017011428.1 PRPF4B
RefSeq:XM_017011425.1 PRPF4B
RefSeq:XM_017011420.1 PRPF4B
RefSeq:XM_017011412.1 PRPF4B
RefSeq:XM_017011423.1 PRPF4B
RefSeq:XM_017011415.1 PRPF4B
RefSeq:XM_017011429.1 PRPF4B
Other Identifiers
11718233_a_at
11718234_a_at
11718235_at
11718236_s_at
11752287_a_at
17004388
202126_PM_at
202126_at
202127_PM_at
202127_at
211090_PM_s_at
211090_s_at
2892739
2892740
2892741
2892743
2892744
2892745
2892746
2892750
2892753
2892754
2892756
2892757
2892759
2892760
2892761
2892762
2892763
2892769
2892776
2892777
2892779
2892780
2892781
2892782
2892783
2892784
2892785
2892786
2892787
2892788
2892789
2892790
2892791
2892792
2892793
2892794
2892795
2892796
2892797
2892798
2892799
32784_at
4019065
4124071
8116664
825_at
8899
A_14_P119049
A_14_P124556
A_23_P168240
A_24_P403168
A_24_P941787
A_33_P3337034
GE61792
GO:0000166
GO:0000398
GO:0003723
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005681
GO:0005694
GO:0006397
GO:0006468
GO:0008380
GO:0016071
GO:0016301
GO:0016310
GO:0016607
GO:0016740
GO:0036211
GO:0043226
GO:0045292
GO:0071013
GO:0106310
GO:0140096
HMNXSV003029609
HMNXSV003035813
Hs.198891.0.S2_3p_at
Hs.198891.0.S3_3p_at
ILMN_1697168
ILMN_1736021
PH_hs_0027972
TC06000035.hg
TC06002505.hg
U48736_at
g405748_3p_s_at
Participates
as an output of
Formation of the Spliceosomal B complex (Homo sapiens)
as a component of
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
as an input of
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
Inferred To
PRP4K [nucleoplasm]
(Sus scrofa)
Ghost homologue of PRPF4B [nucleoplasm]
(Bos taurus)
Ghost homologue of PRPF4B [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of PRPF4B [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of PRPF4B [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of PRPF4B [nucleoplasm]
(Gallus gallus)
Ghost homologue of PRPF4B [nucleoplasm]
(Plasmodium falciparum)
Ghost homologue of PRPF4B [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of PRPF4B [nucleoplasm]
(Xenopus tropicalis)
PRPF4B [nucleoplasm]
(Canis familiaris)
PRPF4B [nucleoplasm]
(Mus musculus)
PRPF4B [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_003904.3
,
XP_016866904.1
,
XP_016866906.1
,
XP_016866909.1
,
XP_016866908.1
,
XP_016866914.1
,
XP_016866916.1
,
XP_016866912.1
,
XP_016866918.1
,
XP_016866910.1
,
XP_016866901.1
,
XP_016866899.1
,
XP_016866903.1
,
XP_016866905.1
,
XP_016866907.1
,
XP_016866900.1
,
XP_016866915.1
,
XP_016866913.1
,
XP_016866919.1
,
XP_016866911.1
,
XP_016866917.1
,
XP_016866902.1
,
XP_016866920.1
ZINC - World Drugs
PRP4B_HUMAN
Guide to Pharmacology - Targets
2177
OpenTargets
ENSG00000112739
ZINC - FDA approved
PRP4B_HUMAN
ZINC - Substances
PRP4B_HUMAN
ZINC - Biogenic
PRP4B_HUMAN
ZINC target
Q13523
PRO
Q13523
PDB
4IJP
,
6CNH
,
4IAN
,
6PJJ
,
6QX9
,
4IFC
,
4IIR
,
6PK6
,
8Y6O
ZINC - Investigational
PRP4B_HUMAN
GeneCards
Q13523
HPA
ENSG00000112739-PRPF4B
Ensembl
ENSP00000433547
,
ENSG00000112739
,
ENST00000480058
,
ENSP00000337194
,
ENST00000337659
Pharos - Targets
Q13523
ZINC - Predictions - Purchasable
PRP4B_HUMAN
HMDB Protein
HMDBP01287
Interactors (32)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.758
4
UniProt:Q86VM9 ZCH18
0.725
5
UniProt:Q9H307 PNN
1
PNN [nucleoplasm]
(R-HSA-9770779)
0.725
5
UniProt:Q15287 RNPS1
2
RNPS1 [nucleoplasm]
(R-HSA-156778)
RNPS1 [cytosol]
(R-HSA-159256)
0.669
4
UniProt:Q9Y2Y9 KLF13
0.645
5
UniProt:O43172 PRPF4
1
PRPF4 [nucleoplasm]
(R-HSA-71890)
0.643
3
UniProt:P78362 SRPK2
1
SRPK2 [cytosol]
(R-HSA-9729332)
0.643
3
UniProt:Q9UPE1 SRPK3
0.643
3
UniProt:Q53GS9 USP39
1
USP39 [nucleoplasm]
(R-HSA-6806793)
0.643
3
UniProt:P04590 GAG
0.633
6
UniProt:Q99459 CDC5L
1
CDC5L [nucleoplasm]
(R-HSA-5420887)
0.527
2
UniProt:P42696 RBM34
0.527
2
UniProt:P38919 EIF4A3
2
EIF4A3 [nucleoplasm]
(R-HSA-8849149)
EIF4A3 [cytosol]
(R-HSA-927868)
0.527
2
UniProt:P62263 RPS14
2
RPS14 [nucleoplasm]
(R-HSA-6790669)
RPS14 [cytosol]
(R-HSA-72333)
0.527
2
UniProt:Q6P2Q9 PRPF8
1
PRPF8 [nucleoplasm]
(R-HSA-83810)
0.527
2
UniProt:P14678 SNRPB
4
SNRPB [nucleoplasm]
(R-HSA-71896)
Me2-R108,R112-SNRPB [nucleoplasm]
(R-HSA-192213)
SNRPB [cytosol]
(R-HSA-191798)
2xMe-SNRPB [cytosol]
(R-HSA-192218)
0.527
2
UniProt:O00422 SAP18
1
SAP18 [nucleoplasm]
(R-HSA-351694)
0.527
3
UniProt:Q8WWY3 PRPF31
1
PRPF31 [nucleoplasm]
(R-HSA-6806772)
0.527
2
UniProt:Q96DI7 SNRNP40
1
SNRNP40 [nucleoplasm]
(R-HSA-71877)
0.527
2
UniProt:Q9P0M6 H2AW
0.527
2
UniProt:O75643 SNRNP200
1
SNRNP200 [nucleoplasm]
(R-HSA-71885)
0.527
2
UniProt:P22492 H1T
0.527
2
UniProt:Q9BSG1 ZNF2
1
ZNF2 [nucleoplasm]
(R-HSA-975031)
0.527
2
UniProt:O94906 PRPF6
1
PRPF6 [nucleoplasm]
(R-HSA-71881)
0.527
2
UniProt:Q15029 EFTUD2
1
EFTUD2 [nucleoplasm]
(R-HSA-71883)
0.527
2
UniProt:Q9BUQ8 DDX23
1
DDX23 [nucleoplasm]
(R-HSA-71879)
0.527
2
UniProt:Q6P5F9 Xpo1
2
Xpo1 [nucleoplasm]
(R-MMU-9769779)
Xpo1 [cytosol]
(R-MMU-165539)
0.527
2
UniProt:Q12906 ILF3
3
p-T188,T315-ILF3 [cytosol]
(R-HSA-9836381)
ILF3 [cytosol]
(R-HSA-450564)
ILF3 [nucleoplasm]
(R-HSA-9760401)
0.527
2
UniProt:O43290 SART1
1
SART1 [nucleoplasm]
(R-HSA-4615999)
0.527
2
UniProt:P62306 SNRPF
2
SNRPF [nucleoplasm]
(R-HSA-71907)
SNRPF [cytosol]
(R-HSA-191852)
0.527
2
UniProt:Q9H1D9 POLR3F
2
POLR3F [cytosol]
(R-HSA-1964434)
POLR3F [nucleoplasm]
(R-HSA-83708)
0.508
2
UniProt:P32121 ARRB2
3
ARRB2 [cytosol]
(R-HSA-416464)
PolyUb-ARRB2 [cytosol]
(R-HSA-6783000)
ARRB2 [endocytic vesicle membrane]
(R-HSA-9910881)
0.499
3
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