Spliceosomal Pre-B complex [nucleoplasm]

Stable Identifier
R-HSA-9769528
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
23222130 Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA

Chang, X, Shi, M, Wu, G, Chi, B, Wang, L, Tan, M, Wang, Q, Cheng, H

Nucleic Acids Res. 2013
30975767 Mechanism of 5' splice site transfer for human spliceosome activation

Charenton, C, Wilkinson, ME, Nagai, K

Science 2019
30315277 Structures of the human pre-catalytic spliceosome and its precursor spliceosome

Shi, Y, Yan, C, Zhang, X, Lei, J, Zhan, X

Cell Res 2018
30765414 Structural Insights into Nuclear pre-mRNA Splicing in Higher Eukaryotes

Will, CL, Lührmann, R, Stark, H, Kastner, B

Cold Spring Harb Perspect Biol 2019
14625303 A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex

Kataoka, N, Dreyfuss, G

J Biol Chem 2004
33243851 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation

Bertram, K, Will, CL, Lührmann, R, Leelaram, MN, Dybkov, O, Agafonov, DE, Stark, H, Urlaub, H, Townsend, C, Kastner, B

Science 2020
27377154 A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity

Tauchert, MJ, Will, CL, Rigo, N, Anokhina, MM, Agafonov, DE, Luhrmann, R, Urlaub, H, Boesler, C, Ficner, R, Kastner, B

Nat Commun 2016
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