Reactome | RBM25 [nucleoplasm]

RBM25 [nucleoplasm]

Stable Identifier

R-HSA-9770250

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

RNA-binding protein 25, RBM25_HUMAN

Locations in the PathwayBrowser for interactor UniProt:O14863 ZNT4

Expand all

External Reference Information

External Reference

UniProt:P49756 RBM25

Gene Names

RBM25, RNPC7

Chain

chain:1-843

Reference Genes

BioGPS Gene:58517 RBM25

COSMIC (genes):RBM25 RBM25

CTD Gene:58517 RBM25

dbSNP Gene:58517 RBM25

ENSEMBL:ENSG00000119707 RBM25

ENSEMBL_homo_sapiens_GENE:ENSG00000119707.14 RBM25

HGNC:23244 RBM25

KEGG Gene (Homo sapiens):58517 RBM25

Monarch:58517 RBM25

NCBI Gene:58517 RBM25

OMIM:612427 RBM25

UCSC:P49756 RBM25

Reference Transcript

Other Identifiers

11743407_a_at

11743408_x_at

11743409_a_at

11743410_a_at

11743411_a_at

11748233_x_at

11754999_x_at

11759493_at

11759711_a_at

16786133

212027_PM_at

212027_at

212028_PM_at

212028_at

212030_PM_at

212030_at

212031_PM_at

212031_at

212033_PM_at

212033_at

236613_PM_at

236613_at

3543412

3543413

3543418

3543419

3543420

3543422

3543424

3543425

3543426

3543427

3543431

3543432

3543433

3543434

3543435

3543436

3543437

3543438

3543439

3543440

3543441

3543442

3543443

3543444

3543447

3543450

3543452

3543453

3543454

3543458

3543459

3543460

3543463

3543464

3543465

3543466

3543467

3543468

3543469

3543474

3543476

3543478

3543480

41208_at

51349_at

58517

59422_at

64008_at

7975521

A_23_P99762

A_24_P290572

GE54816

GE696978

GE80337

GO:0000381

GO:0003676

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0006397

GO:0008380

GO:0012501

GO:0016071

GO:0016607

GO:0042981

GO:0043226

HMNXSV003038447

Hs.166895.0.A1_3p_at

Hs.180789.0.S1_3p_at

Hs.180789.0.S2_3p_at

Hs.180789.0.S3_3p_at

Hs.180789.0.S4_3p_at

Hs.180789.0.S5_3p_at

ILMN_1768117

L40392_at

PH_hs_0022960

TC14000438.hg

Participates

as an output of

Formation of the Spliceosomal B complex (Homo sapiens)

as an input of

Formation of the Spliceosomal E complex (Homo sapiens)

as a component of

Inferred To

Homologues of RBM25 [nucleoplasm] (Rattus norvegicus)

rbm-25 [nucleoplasm] (Caenorhabditis elegans)

usp107 [nucleoplasm] (Schizosaccharomyces pombe)

RBM25 [nucleoplasm] (Bos taurus)

RBM25 [nucleoplasm] (Canis familiaris)

RBM25 [nucleoplasm] (Dictyostelium discoideum)

RBM25 [nucleoplasm] (Plasmodium falciparum)

RBM25 [nucleoplasm] (Sus scrofa)

Ghost homologue of RBM25 [nucleoplasm] (Gallus gallus)

rbm25 [nucleoplasm] (Xenopus tropicalis)

Rbm25 [nucleoplasm] (Mus musculus)

Rbm25 [nucleoplasm] (Rattus norvegicus)

BcDNA.LD23634 [nucleoplasm] (Drosophila melanogaster)

Rbm25l1 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

XP_011535346.1, NP_067062.1, XP_011535347.1

OpenTargets

ENSG00000119707

GeneCards

P49756

HPA

ENSG00000119707-RBM25

Ensembl

ENST00000528081, ENST00000525321, ENST00000527432, ENSP00000436225, ENSP00000434444, ENST00000526754, ENSG00000119707, ENSP00000261973, ENSP00000431150, ENST00000261973, ENSP00000436868

PRO

P49756

Pharos - Targets

P49756

PDB

3V53

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q86VM9 ZCH18			0.643	3
UniProt:O75417 POLQ	1	POLQ [nucleoplasm] (R-HSA-5687494)	0.564	2
UniProt:O75400 PRPF40A	1	PRPF40A [nucleoplasm] (R-HSA-8867890)	0.564	2
UniProt:A7MD48 SRRM4			0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q53F19 NCBP3			0.527	2
UniProt:O14863 ZNT4			0.527	2
UniProt:P09234 SNRPC	1	SNRPC [nucleoplasm] (R-HSA-8865876)	0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	4

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