Reactome | RBM39 [nucleoplasm]

RBM39 [nucleoplasm]

Stable Identifier

R-HSA-9770254

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

fullName evidence="18"RNA-binding protein 39, RBM39_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q8TBK6 ZCH10

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External Reference Information

External Reference

UniProt:Q14498 RBM39

Gene Names

RBM39, HCC1, RNPC2

Chain

initiator methionine:, chain:2-530

Reference Genes

COSMIC (genes):RBM39 RBM39

dbSNP Gene:9584 RBM39

ENSEMBL:ENSG00000131051 RBM39

Participates

as an input of

Formation of the Spliceosomal E complex (Homo sapiens)

as a component of

as an output of

Formation of the Spliceosomal B complex (Homo sapiens)

Inferred To

RBM23 [nucleoplasm] (Gallus gallus)

RBM39 [nucleoplasm] (Bos taurus)

RBM39 [nucleoplasm] (Canis familiaris)

RBM39 [nucleoplasm] (Plasmodium falciparum)

RBM39 [nucleoplasm] (Sus scrofa)

rsd1 [nucleoplasm] (Schizosaccharomyces pombe)

Caper [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of RBM39 [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of RBM39 [nucleoplasm] (Dictyostelium discoideum)

Rbm39 [nucleoplasm] (Mus musculus)

Rbm39 [nucleoplasm] (Rattus norvegicus)

rbm39 [nucleoplasm] (Xenopus tropicalis)

Interactors (46)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P78362 SRPK2	1	SRPK2 [cytosol] (R-HSA-9729332)	0.908	12
UniProt:O00422 SAP18	1	SAP18 [nucleoplasm] (R-HSA-351694)	0.871	12
UniProt:P49760 CLK2			0.782	9
UniProt:Q96SB4 SRPK1	2	SRPK1 [nucleoplasm] (R-HSA-9821984) SRPK1 [cytosol] (R-HSA-9729349)	0.723	4
UniProt:Q9NVV9 THAP1			0.718	6
UniProt:Q6ZUT1 NKAP1			0.718	6
UniProt:O75400-2 PRPF40A			0.718	6
UniProt:Q13427 PPIG	2	PPIG [nucleoplasm] (R-HSA-9769592) PPIG [cytosol] (R-HSA-9728768)	0.666	4
UniProt:Q15427 SF3B4	1	SF3B4 [nucleoplasm] (R-HSA-71975)	0.666	4
UniProt:Q8TBK6 ZCH10			0.666	4
UniProt:P67870 CSNK2B	5	CSNK2B [cytosol] (R-HSA-201693) CSNK2B [nucleoplasm] (R-HSA-6805067) CSNK2B [secretory granule lumen] (R-HSA-6801319) CSNK2B [extracellular region] (R-HSA-6806508) CSNK2B [ficolin-1-rich granule lumen] (R-HSA-6801290)	0.666	4
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	14
UniProt:Q15365 PCBP1	1	PCBP1 [nucleoplasm] (R-HSA-71919)	0.564	3
UniProt:Q05519 SRSF11	1	SRSF11 [nucleoplasm] (R-HSA-72058)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.556	3
UniProt:Q8N9Q2 SR1IP			0.556	3
UniProt:Q92997 DVL3	4	pp-DVL3 [cytosol] (R-HSA-3772400) p-DVL3 [cytosol] (R-HSA-201680) DVL3 [cytosol] (R-HSA-201678) ub-DVL3 [cytosol] (R-HSA-4652688)	0.556	3
UniProt:Q96MA6 AK8	1	AK8 [cytosol] (R-HSA-6788788)	0.556	3
UniProt:Q8IXK0 PHC2	1	PHC2 [nucleoplasm] (R-HSA-389112)	0.556	3
UniProt:hCG_1744368 A0A024RA76			0.556	3
UniProt:Q05519-2 SRSF11			0.556	5
UniProt:Q6ZUT1-2 NKAPD1			0.556	3
UniProt:Q66PJ3-3 ARL6IP4			0.556	3
UniProt:P13473-2 P134732			0.556	3
UniProt:A7MD48 SRRM4			0.556	3
UniProt:P78424 PO6F2			0.556	3
UniProt:Q7Z7F0 KHDC4			0.556	3
UniProt:Q8WXA9 SREK1			0.556	3
UniProt:P68400 CSNK2A1	2	CSNK2A1 [cytosol] (R-HSA-201713) CSNK2A1 [nucleoplasm] (R-HSA-6805057)	0.556	3
UniProt:Q9C086 INO80B	1	INO80B [nucleoplasm] (R-HSA-5689599)	0.556	3
UniProt:P59991 KRTAP12-2	1	KRTAP12-2 [cytosol] (R-HSA-6810271)	0.556	3
UniProt:O43395 PRPF3	1	PRPF3 [nucleoplasm] (R-HSA-6806806)	0.547	2
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:Q6NYC1 JMJD6	1	JMJD6 [nucleoplasm] (R-HSA-4754226)	0.527	4
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.527	2
UniProt:P38919 EIF4A3	2	EIF4A3 [nucleoplasm] (R-HSA-8849149) EIF4A3 [cytosol] (R-HSA-927868)	0.527	2
UniProt:Q09161 NCBP1	2	NCBP1 [nucleoplasm] (R-HSA-51469) NCBP1 [cytosol] (R-HSA-162459)	0.527	3
UniProt:Q53F19 NCBP3			0.527	2
UniProt:Q9UPE1 SRPK3			0.527	2
UniProt:P61326 MAGOH	1	MAGOH [nucleoplasm] (R-HSA-156658)	0.527	2
UniProt:Q99459 CDC5L	1	CDC5L [nucleoplasm] (R-HSA-5420887)	0.527	2
UniProt:O75940 SMNDC1	1	SMNDC1 [nucleoplasm] (R-HSA-8865958)	0.483	2
UniProt:P09651 HNRNPA1	2	HNRNPA1 [nucleoplasm] (R-HSA-71927) HNRNPA1 [cytosol] (R-HSA-9727902)	0.483	2
UniProt:O75152 ZC3H11A	1	ZC3H11A [nucleoplasm] (R-HSA-8850659)	0.483	2
UniProt:Q16629 SRSF7	1	SRSF7 [nucleoplasm] (R-HSA-72029)	0.483	2
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.462	2